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| 2005 || April 25 || Administration || The Global Fund approves 33 grants to enter phase 2.<ref name="Global health the Global Fund to fight AIDS, TB and malaria is responding to challenges but needs better information and documentation for performancebased funding : report to congressional committees."/> ||

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| 2005 || August || Withdraw || The Global Fund withdraws from Burma due to new local government restrictions to project sites and more complicated regulations regarding the procurement of medical supplies.<ref>{{cite book|last1=Dittmer|first1=Lowell|title=Burma Or Myanmar?: The Struggle for National Identity|url=https://books.google.com.ar/books?id=aoHP2Q2I1p4C&pg=PA97&lpg=PA97&dq=The+Global+Fund+to+Fight+AIDS,+Tuberculosis+and+Malaria+%22in+august%22&source=bl&ots=CaIaQSNN-U&sig=9jK-a75tUn-lxBJ8IaAFOZPcmLc&hl=en&sa=X&ved=0ahUKEwizq5iG7dzTAhUFgJAKHZy_BSk4ChDoAQggMAA#v=onepage&q=The%20Global%20Fund%20to%20Fight%20AIDS%2C%20Tuberculosis%20and%20Malaria%20%22in%20august%22&f=false|accessdate=7 May 2017}}</ref> || [[wikipedia:Burma|Burma]]

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| 2007 || November || Administration || The Global Fund holds its Sixteenth Board Meeting. The Board approves 73 grants in Round 7 of funding for a total of US$1.1 billion, for 136 countries.<ref name="Global Fund Overview"/> || [[wikipedia:China|China]] ([[wikipedia:Kunming|Kunming]])

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| 2008 || || Administration || The Global Fund starts to promote the inclusion of Operational/implementation research (OR/IR) activities in disease control programs it supports.<ref>{{cite web|title=Operational and implementation research within Global Fund to Fight AIDS, Tuberculosis and Malaria grants: a situation analysis in six countries|url=https://globalizationandhealth.biomedcentral.com/articles/10.1186/s12992-017-0245-5|website=biomedcentral.com|accessdate=7 May 2017}}</ref> ||

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| 2008 || November || Administration || The Global Fund holds its Eighteenth Board Meeting. The Board approves 94 Round 8 grants for a total value of US$2.75 billion (the highest amount ever approved). The Round 9 Call for Proposals is launched.<ref name="Global Fund Overview"/> || [[wikipedia:India|India]] ([[wikipedia:New Delhi|New Delhi]])

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| 2009 || November || Administration || The Global Fund holds its Twentieth Board Meeting. The Board approves Round 9 grants for a total value of US$2.4 billion.<ref name="Global Fund Overview"/> || [[wikipedia:Ethiopia|Ethiopia]] ([[wikipedia:Addis Abeba|Addis Abeba]])

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| 2012 || || Report || Data released from analysis from Round 1 (2002) to Round 9 (2009) shows that the Global Fund has invested or approved US$ 430 million for activities that specifically targets people who inject drugs.<ref name="The Global Fund to Fight AIDS, Tuberculosis and Malaria's investments in harm reduction through the rounds-based funding model (2002–2014)"/> ||

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| 2013 || February || Administration || The Global Fund announces a new funding model, under which funding allocations would be determined for each eligible country based on calculations of country income and national disease burden.<ref name="The Global Fund to Fight AIDS, Tuberculosis and Malaria's investments in harm reduction through the rounds-based funding model (2002–2014)">{{cite journal|title=The Global Fund to Fight AIDS, Tuberculosis and Malaria's investments in harm reduction through the rounds-based funding model (2002–2014)|doi=10.1016/j.drugpo.2015.08.001|url=http://www.sciencedirect.com/science/article/pii/S0955395915002364|accessdate=5 May 2017}}</ref> ||

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| 2016 || September || Administration || The Global Fund holds the Pledging conference for its Fifth Replenishment, hosted by Canadian Prime Minister [[wikipedia:Justin Trudeau|Justin Trudeau]]. Donor countries, foundations, and private donors pledge US$12.9 billion for the 2017–2019 period. <ref name="Global Fund Overview"/> || [[wikipedia:Canada|Canada]] ([[wikipedia:Montreal|Montreal]])

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