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| 1986 || Statistics || The United States Congress Office of Technology Assessment reports that estimates of the animals used in the United States range from 10 million to upwards of 100 million each year, and that their own best estimate is at least 17 million to 22 million.<ref>''Alternatives to Animal Use in Research, Testing and Education'', U.S. Congress Office of Technology Assessment, Washington, D.C.:Government Printing Office, 1986, p. 64. In 1966, the Laboratory Animal Breeders Association estimated in testimony before Congress that the number of mice, rats, guinea pigs, hamsters, and rabbits used in 1965 was around 60 million. (Hearings before the Subcommittee on Livestock and Feed Grains, Committee on Agriculture, U.S. House of Representatives, 1966, p. 63.)</ref> || {{w|United States}}
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| 1986 || Policy || The Council of Europe Convention for the Protection of Vertebrate Animals used for Experimental and other Scientific Purposes (ETS123) is established by the {{w|European Union}}<ref name="sdf"/>, with the purpose to reduce the number of animals used in research and encouraging signing parties to use animals only where alternatives do not exist. The document laids down establishes general principles for when and how experiments with animals are to be carried out and also provides technical details on how to house animals.<ref>{{cite journal |last1=Olsson |first1=Anna S |last2=Pinto da Silva |first2=Sandra |last3=Townend |first3=David |last4=Sandøe |first4=Peter |title=Protecting Animals and Enabling Research in the European Union: An Overview of Development and Implementation of Directive 2010/63/EU |doi=10.1093/ilar/ilw029 |url=https://academic.oup.com/ilarjournal/article/57/3/347/3796590}}</ref> || {{w|European Union}}
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| 1986 || Policy || The {{w|Animals (Scientific Procedures) Act 1986}} is passed by the {{w| Parliament of the United Kingdom}}. It regulates the use of protected animals in any experimental or other scientific procedure which may cause pain, suffering, distress or lasting harm to the animal.<ref>{{cite web |title=Animal Research at Nottingham |url=https://www.nottingham.ac.uk/animalresearch/legislation/legislation.aspx |website=nottingham.ac.uk |accessdate=28 April 2019}}</ref> || {{w|United Kingdom}}
