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Timeline of animal testing

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| 1968 || Animal testing || First animals are sent in deep space and to circle the Moon. The Soviet Zond 5 becomes the first spacecraft to circle the satellite, carrying a payload of two Russian tortoises, wine flies, mealworms, plants, seeds and bacteria.<ref name="Cosmic Menagerie: A History of Animals in Space (Infographic)"/> ||
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| 1969 || Alternative testing || The {{w|Fund for the Replacement of Animals in Medical Experiments}} is formed with the purpose to relieve the suffering of animals used as subjects in biomedical research, and to promote and support research into acceptable new techniques as substitutes for the use of animals in all such research.<ref>{{cite web |last1=Balls |first1=Michael |last2=Fentem |first2=Julia H. |title=The Fund for the Replacement of Animals in Medical Experiments (FRAME): 23 Years of Campaigning for the Three Rs |url=https://onlinelibrary.wiley.com/doi/abs/10.1002/9783527616053.ch5 |website=onlinelibrary.wiley.com |accessdate=22 October 2018}}</ref> || {{w|United Kingdom}}
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| 1970s || Animal testing || Australian psychiatrist {{w|John Cade}} uses lithium salts in {{w|guinea pig}}s in his investigation to find a treatment for depression and other manic conditions.<ref name="History of Animal Testing"/> ||
| 2004 || Policy || A law phasing out the production and sale of animal tested cosmetics is passed by the {{w|European Union}}.<ref name="Timeline: Cosmetics Testing on Animals"/> || {{w|European Union}}
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| 2004 || Policy Alternative testing || The {{w|Organization for Economic Cooperation and Development}} (OECD) approves non-animal alternative tests for dermal absorption, dermal corrosivity, and dermal phototoxicity.<ref name="Timeline: Cosmetics Testing on Animals"/> ||
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| 2004 || Alternative testing || The British National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) is established.<ref>{{cite journal |last1=Singh |first1=Jatinder |title=The national centre for the replacement, refinement, and reduction of animals in research |pmid=22368436 |url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284057/ |pmc=3284057}}</ref> || {{w|United Kingdom}}|-| 2005 || Policy Alternative testing || The Japanese Center for the Validation of Alternative Methods (JaCVAM) is established.<ref name="Timeline: Cosmetics Testing on Animals"/> || {{w|Japan}}
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| 2007 || Statistics || As of date, the {{w|United States}} and {{w|Gabon}} are the only countries that still use {{w|chimpanzee}}s for research purposes.<ref name=sciencemag>{{cite journal|url=http://science.sciencemag.org/content/315/5811/450|title=The Endangered Lab Chimp|first=Jon|last=Cohen|date=26 January 2007|publisher=|journal=Science|volume=315|issue=5811|pages=450–452|accessdate=6 October 2018|via=www.sciencemag.org|doi=10.1126/science.315.5811.450|pmid=17255486}}</ref><ref>{{cite web|url=http://altweb.jhsph.edu/bin/g/c/paper111.pdf|title=Chimpanzees in research and testing worldwide: Overview, oversight and applicable laws|author=|date=|website=jhsph.edu|accessdate=6 October 2018}}</ref> || {{w|United States}}, {{w|Gabon}}
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| 2015 (December) || Policy || Canada reintroduces the Cruelty-Free Cosmetics Act.<ref name="Timeline: Cosmetics Testing on Animals"/> || {{w|Canada}}
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| 2015 || Alternative testing || The Romanian Center for Alternative Test Methods (ROCAM) is established to promote the application of alternative methods in industry and their acceptance by regulators in Romania and also the development of new methods and approaches.<ref>{{cite web |title=Romanian Center for Alternative Test Methods (ROCAM) |url=http://rocam.usamvcluj.ro/ |website=rocam.usamvcluj.ro |accessdate=22 October 2018}}</ref> || {{w|Romania}}
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| 2015 || Statistics || An article published in the ''{{w|Journal of Medical Ethics}}'' argues that the use of animals in the United States dramatically increased in recent years. Researchers find this increase is largely the result of an increased reliance on genetically modified mice in animal studies.<ref name="GoodmanChandnaRoe">{{cite journal |last1=Goodman |first1=J. |last2=Chandna |first2=A. |last3=Roe |first3=K. |title=Trends in animal use at US research facilities |journal=Journal of Medical Ethics |date=2015 |doi=10.1136/medethics-2014-102404 |pmid=25717142 |url=http://jme.bmj.com/content/early/2015/01/27/medethics-2014-102404.abstract |accessdate=6 October 2018 |volume=41 |issue=7 |pages=567–569}}</ref> || {{w|United States}}
| 2017 (June) || Policy || The Humane Cosmetics Act is reintroduced in the United States.<ref name="Timeline: Cosmetics Testing on Animals"/> || {{w|United States}}
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| 2017 (October) || Policy Alternative testing || New alternative test methods for ocular toxicity and skin allergy are approved by {{w|OECD}}.<ref name="Timeline: Cosmetics Testing on Animals"/> ||
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| 2017 (December) || Policy || Legislation banning sale of animal-tested cosmetics is introduced in South Africa.<ref name="Timeline: Cosmetics Testing on Animals"/> || {{w|South Africa}}
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