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| 2001 || Medical development (device) || [[wikipedia:AbioCor|AbioCor]] total [[wikipedia:artificial heart|artificial heart]] is implanted in a 59-year-old man. The TAH is developed by company [[wikipedia:AbioMed|AbioMed]].<ref>{{cite web|url=http://www.texasheart.org/Research/Devices/abiocor.cfm|title=AbioCor|author=|date=|accessdate=31 July 2016}}</ref>||[[wikipedia:Jewish Hospital (Louisville, Kentucky)|Jewish Hospital]], [[wikipedia:Louisville, Kentucky|Louisville]], [[wikipedia:Kentucky|Kentucky]]
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| 2002 || Medical development || Alain Cribier performs the first percutaneous aortic valve replacement.<ref name="Handbook of Polymer Applications in Medicine and Medical Devices: 8. Review of Research in Cardiovascular Devices"/> ||
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| 2004 || Scientific development || Serum [[wikipedia:aldosterone|aldosterone]] levels are found to predict future risk of hypertension in non-hypertensive individuals.<ref name=framinghamheartstudy/><ref>{{cite journal |author=Ramachandran S. Vasan, M.D., Jane C. Evans, D.Sc., Martin G. Larson, Sc.D., Peter W.F. Wilson, M.D., James B. Meigs, M.D., M.P.H., Nader Rifai, Ph.D., Emelia J. Benjamin, M.D., Daniel Levy, M.D. |date= |title=Serum Aldosterone and the Incidence of Hypertension in Nonhypertensive Persons|url=http://www.nejm.org/doi/full/10.1056/NEJMoa033263#t=article|journal= New England Journal of Medicine|publisher= |volume= 351|issue= |pages= 33–41|doi=10.1056/NEJMoa033263 |pmc= |pmid= }}</ref>||[[wikipedia:Boston Medical Center|Boston Medical Center]], [[wikipedia:U.S.A|U.S.A]]
