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Timeline of malaria

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| 1500s–1600s || Malaria reaches the Americas through Spanish colonization. The [[wikipedia:Indigenous peoples of the Americas|native population]] in Peru makes use of bark of the [[wikipedia:cinchona|cinchona]] tree for treating fever.<ref name="butler_khan">{{cite journal |vauthors=Butler AR, Khan S, Ferguson E | title = A brief history of malaria chemotherapy| journal = J R Coll Physicians Edinb | volume = 40| issue = 2| pages = 172–7 | year = 2010| pmid = 20695174| url = http://www.rcpe.ac.uk/journal/issue/journal_40_2/butler.pdf | doi = 10.4997/JRCPE.2010.216}}</ref> After its discovery by the Spanish, the bark is brought to Europe where it comes into general use.<ref name=butler_khan/><ref name=Chwatt>{{cite journal |author=Bruce-Chwatt LJ |title=Three hundred and fifty years of the Peruvian fever bark |journal=Br Med J (Clin Res Ed) |volume=296 |issue=6635 |pages=1486–7 |year=1988 |pmid=3134079 |pmc=2546010 |doi=10.1136/bmj.296.6635.1486 }}</ref><ref>{{cite journal |vauthors=De Castro MC, Singer BH | title = Was malaria present in the Amazon before the European conquest? Available evidence and future research agenda| journal =J Achaeol Sci | volume = 32| pages =337–340| year = 2005|doi = 10.1016/j.jas.2004.10.004 | issue = 3}}</ref><ref>{{cite journal |vauthors=Yalcindag E, Elguero E, Arnathau C, Durand P, Akiana J, Anderson TJ, Aubouy A, Balloux F, Besnard P, Bogreau H, Carnevale P, D'Alessandro U, Fontenille D, Gamboa D, Jombart T, Le Mire J, Leroy E, Maestre A, Mayxay M, Ménard D, Musset L, Newton PN, Nkoghé D, Noya O, Ollomo B, Rogier C, Veron V, Wide A, Zakeri S, Carme B, Legrand E, Chevillon C, Ayala FJ, Renaud F, Prugnolle F | title = Multiple independent introductions of Plasmodium falciparum in South America | journal =PNAS| year = 2011|doi = 10.1073/pnas.1119058109 |url = http://www.pnas.org/content/early/2011/12/19/1119058109 | volume = 109 | issue = 2 | pages = 511–6 | pmid = 22203975 | pmc = 3258587| bibcode = 2012PNAS..109..511Y }}</ref>
|-
|1700s || The [[wikipedia:cinchona|cinchona]] bark from [[wikipedia:South America|South America]] is established as a major cure for fever in the Western World.<ref name="Evaluation of Cinchona bark in the 17th and 18th centuries" /> Malaria spontaneously begins to disappear in Europe.<ref name="Biodiversity of Malaria in the world" />
|-
| 1800s || Parasites are first identified as source of malaria.<ref name="journey-of-scientific-discoveries" />
== Visual data ==
<gallery align="center" perrow="2" widths="370550" heights="370550" mode="nolines">
File:Funding for malaria control by the Global Fund in countries belonging to African WHO region, for the period 2013-2015. Table 1.png|thumb|Funding for malaria control by the Global Fund in countries belonging to African WHO region, for the period 2013-2015. Table 1.
File:Funding for malaria control by the Global Fund in countries belonging to African WHO region, for the period 2013-2015. Table 2..png|Funding for malaria control by the Global Fund in countries belonging to African WHO region, for the period 2013-2015. Table 2.
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| 2700 BC || Publication || Chinese text ''[[wikipedia:Huangdi Neijing|Nei Ching]]'' (The Canon of Medicine) is published. It describes several characteristic symptoms of what would later be named malaria.<ref name="The History of Malaria, an Ancient Disease" /> || [[wikipedia:China|China]]
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| 1600 BC || Science development || [[wikipedia:Vedas|Vedic]] writings describe accounts of malaria.<ref name="Malaria: Introduction">{{cite web|title=Malaria: Introduction|url=https://www.infoplease.com/science/health-and-body/malaria-introduction|website=infoplease.com|accessdate=25 June 2017}}</ref> || [[wikipedia:India|India]]
|-
| 2000–1500 BC || Science development (symptoms) ||Sumerian and Egyptian doctors describe symptoms resembling those of malaria.<ref name="Spatial Agent-Based Simulation Modeling in Public Health: Design ...">{{cite book|last1=Niaz Arifin|first1=S. M.|last2=Madey|first2=Gregory R.|last3=Collins|first3=Frank H.|title=Spatial Agent-Based Simulation Modeling in Public Health: Design ...|url=https://books.google.com.ar/books?id=UvelCgAAQBAJ&pg=PA8&lpg=PA8&dq=%22sumerian%22+%22egyptian%22+%22malaria%22+%22symptoms%22&source=bl&ots=rKhspW6Qci&sig=qvbhcsE9aSM_5J93PTwgLv3GkRA&hl=en&sa=X&ved=0ahUKEwiVw9X2o_fQAhWJPpAKHTnuDWQQ6AEIMzAE#v=onepage&q=%22sumerian%22%20%22egyptian%22%20%22malaria%22%20%22symptoms%22&f=false|accessdate=15 December 2016}}</ref> || [[wikipedia:Middle East|Middle East]]
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| 1492 onwards || Epidemic || The arrival of Europeans introduces the malaria parasite for the first time into the Americas.<ref name="Spatial Agent-Based Simulation Modeling in Public Health: Design ..." /> || [[wikipedia:Americas|Americas]]
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| 1607 || Epidemic || Malaria devastates the [[wikipedia:Jamestown, Virginia|Jamestown settlement]] in the [[wikipedia:Colony of Virginia|Colony of Virginia]].<ref name="Malaria: Introduction"/> || [[wikipedia:United States|United States]]
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| 1632 || || Jesuit missionary [[wikipedia:Bernabé Cobo|Bernabé Cobo]] brings cinchona bark from [[wikipedia:Perú|Perú]] to [[wikipedia:Spain|Spain]].<ref name="Saga of Malaria Treatment" /><ref name="Kill or Cure: An Illustrated History of Medicine">{{cite book|last1=Parker|first1=Steve|title=Kill or Cure: An Illustrated History of Medicine|url=https://books.google.com.ar/books?id=vWwrAQAAQBAJ&pg=PA388&lpg=PA388&dq=%221632%22+%22cobo%22+%22cinchona%22&source=bl&ots=K8fcQTOB7m&sig=HHcqP4mui_oqqKOyjOBuq_bDHKg&hl=en&sa=X&ved=0ahUKEwjR_8CR5r_QAhUGEZAKHUjFBqYQ6AEIJzAC#v=onepage&q=%221632%22%20%22cobo%22%20%22cinchona%22&f=false|accessdate=23 November 2016}}</ref>|| [[wikipedia:Spain|Spain]]
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| 1821 || Science development (treatment) ||French pharmacist [[wikipedia:Joseph Bienaimé Caventou|Joseph Bienaimé Caventou]] and chemist [[wikipedia:Pierre Joseph Pelletier|Pierre Joseph Pelletier]] purify [[wikipedia:quinine|quinine]] (obtained from the [[wikipedia:cinchona|cinchona]] tree) and other cinchona alkaloids. The quinine molecule is promptly tested in patients, and after numerous medical observations and case reports from all over the world, it is soon indicated that quinine is specific for ‘malarial’ (intermittent) fevers.<ref name="Evaluation of Cinchona bark in the 17th and 18th centuries" />|| [[wikipedia:France|France]] ([[wikipedia:Paris|Paris]])
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| 1822 || Science development (treatment) || [[wikipedia:Quinine|Quinine]] is first used as a drug in Senegal.<ref name="Biodiversity of Malaria in the world"/> || [[wikipedia:Senegal|Senegal]]
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| 1874 || Science development (prevention) || Austrian chemistry student [[wikipedia:Othmar Zeidler|Othmar Zeidler]] is credited with the first synthesis of [[wikipedia:DDT|DDT]] (Dichloro Diphenyl Trichloroethane). DDT is used in the second half of World War II to control malaria and typhus among civilians and troops. After the war, DDT is also used as an agricultural insecticide.<ref>{{cite book|last1=Eckinger|first1=Julie|title=The Ethics of Intensification: Agricultural Development and Cultural Change|url=https://books.google.com.ar/books?id=0K8qkYZdx7cC&pg=PA66&lpg=PA66&dq=%22Othmar+Zeidler%22+%221874%22+%22synthesis%22+%22DDT%22&source=bl&ots=v-Z81xzu5t&sig=gMzdYjUNTDBNlF9L3fpjcZjaOf0&hl=en&sa=X&ved=0ahUKEwja067Si8XQAhXClJAKHfsUCJkQ6AEINjAG#v=onepage&q=%22Othmar%20Zeidler%22%20%221874%22%20%22synthesis%22%20%22DDT%22&f=false|accessdate=25 November 2016}}</ref> || [[wikipedia:Austria|Austria]]<ref>{{cite book|last1=Jones|first1=Richard|title=Mosquito|url=https://books.google.com.ar/books?id=d2N9Mxztdu4C&pg=PA152&lpg=PA152&dq=%22Othmar+zeidler%22+%22DDT%22+%22Austria%22&source=bl&ots=dJBZzwoG-a&sig=USzifY6NObI0-T7htt59TJGeLRU&hl=en&sa=X&ved=0ahUKEwjdp56tu4jRAhXMf5AKHW7MDdYQ6AEINTAG#v=onepage&q=%22Othmar%20zeidler%22%20%22DDT%22%20%22Austria%22&f=false|accessdate=22 December 2016}}</ref>
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| 1875 || || The [[wikipedia:Incidence (epidemiology)|incidence]] of malaria peaks in the United States.<ref name="Malaria: Introduction"/> || [[wikipedia:United States|United States]]|-| 1880 || Science development (parasite) || french physician [[wikipedia:Charles Louis Alphonse Laveran|Charles Louis Alphonse Laveran]] observes parasites inside the red blood cells of infected people for the first time, proposing that malaria is caused by an organism. For this he receives the [[wikipedia:Nobel Prize|Nobel Prize]] in 1907.<ref name= journey-of-scientific-discoveries>{{cite web |title=Journey of Scientific Discoveries |url=http://www.malariasite.com/history-science/|publisher=Malaria Site|accessdate=15 December 2016}}</ref> || [[wikipedia:Algeria|Algeria]]
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| 1881 || Science development (vector) || [[wikipedia:Carlos Finlay|Carlos Finlay]] provides strong evidence that a mosquito later designated as ''[[wikipedia:Aedes aegypti|Aedes aegypti]]'' transmits disease to and from humans.<ref>{{cite journal|title=Carlos Juan Finlay: Rejected, Respected, and Right|doi=10.1097/EDE.0b013e3181c308e0|url=http://journals.lww.com/epidem/Fulltext/2010/01000/Carlos_Juan_Finlay__Rejected,_Respected,_and_Right.28.aspx|accessdate=28 November 2016|volume=21|journal=Epidemiology|pages=158}}</ref><ref>{{cite journal|author=Finlay CJ.|title=El mosquito hipotéticamente considerado como agente de transmision de la fiebre amarilla|journal=Anales de la Real Academia de Ciencias Médicas Físicas y Naturales de la Habana|date=1881|issue=18|pages=147–169}}</ref> The theory remains controversial for twenty years until confirmed in 1901 by [[wikipedia:Walter Reed|Walter Reed]].<ref>{{cite journal |vauthors=Reed W, Carroll J, Agramonte A |title= The Etiology of Yellow Fever|journal= JAMA|volume= 36|issue= 7|pages= 431–440 |year= 1901|doi=10.1001/jama.1901.52470070017001f}}</ref>|| [[wikipedia:Cuba|Cuba]]
| 1890 || Science development (parasite) ||Italian physicians [[wikipedia:Giovanni Batista Grassi|Giovanni Batista Grassi]] and [[wikipedia:Raimondo Feletti|Raimondo Feletti]] first introduce the names ''[[wikipedia:plasmodium vivax|plasmodium vivax]]'' and ''[[wikipedia:plasmodium malariae|plasmodium malariae]]'' for two of the malaria parasites that affect humans.<ref name="The History of Malaria, an Ancient Disease" /> || [[wikipedia:Italy|Italy]]
|-
| 1895–1898 1890 || Science development || American microbiologists [[wikipedia:Theobald Smith|Theobald Smith]] and Frederick Kilborne observe that young ticks taken from cattle infected with the [[wikipedia:piroplasm|piroplasm]] ''[[wikipedia:Babesia bigemina|Babesia bigemina]]'', an intraerythrocytic [[wikipedia:protozoa|protozoan]] resembling a malaria parasite, could infect susceptible animals. This would be confirmed in a series of meticulously controlled experiments over the next two years.<ref name="History of the discovery of the malaria parasites and their vectors"/> |||-| 1897 || Science development (vector) || British [[wikipedia:medical doctor|medical doctor]] [[wikipedia:Ronald Ross|Ronald Ross]] proves , working in India, discovers that mosquito subfamily ''[[wikipedia:Culicinae|Culicinae]]'' transmit the avian malaria is transmitted by mosquitoes, and lays the foundation for the method of combating the disease. For this he receives the parasite ''[[wikipedia:Nobel Prize in Physiology or MedicinePlasmodium relictum|Nobel PrizePlasmodium relictum]] in 1902'' and suggests that human malaria parasites might also be transmitted by mosquitoes.<ref name= journey-"History of the discovery of-scientific-discoveriesthe malaria parasites and their vectors"/> || [[wikipedia:India|India]]
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| 1897 || Science development (parasite) ||American bacteriologist [[wikipedia:William H. Welch|William H. Welch]] names the malignant tertian malaria parasite ''[[wikipedia:plasmodium falciparum|plasmodium falciparum]]''.<ref name="The History of Malaria, an Ancient Disease" />
|data-sort-value="United States" | [[wikipedia:United States|United States]]
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| 1897 || Science development || Canadian pathologist [[wikipedia:William George MacCallum|William George MacCallum]] discovers the sexual stages of malaria parasites in the blood in birds infected with a related [[wikipedia:Haematozoa|haematozoan]], ''[[wikipedia:Haemoproteus columbae|Haemoproteus columbae]]''.<ref name="History of the discovery of the malaria parasites and their vectors"/>|||-| 1898 || Science development (vector) || An Italian team of scientists prove led by [[wikipedia:Giovanni Battista Grassi|Giovanni Battista Grassi]] proves that ''[[wikipedia:anopheles claviger|anopheles claviger]]'' mosquitoes infect humans via the bite.<ref name="History of the discovery of the malaria parasites and their vectors">{{cite journal|title=History of the discovery of the malaria parasites and their vectors|doi=10.1186/1756-3305-3-5|pmc=2825508|pmid=20205846|volume=3|year=2010|journal=Parasit Vectors|pages=5 | last1 = Cox | first1 = FE}}</ref>
|data-sort-value="Italy" | [[wikipedia:Italy|Italy]] ([[wikipedia:Rome|Rome]])
|-
| 1899 || Science development || [[wikipedia:Ronald Ross|Ronald Ross]], working in Sierra Leone, demonstrates that the human malaria parasites are transmitted by mosquito genus ''[[wikipedia:anopheles|Anopheles]]''.<ref name="History of the discovery of the malaria parasites and their vectors"/> || [[wikipedia:Sierra Leone|Sierra Leone]]
|-
| 1899 || Science development || [[wikipedia:Charles Louis Alphonse Laveran|Charles Louis Alphonse Laveran]] first recognizes malaria-like parasites belonging to the genus ''[[wikipedia:Hepatocystis|Hepatocystis]]'' in non-human primates.<ref name="History of the discovery of the malaria parasites and their vectors"/> ||
|-
| 1899 || Science development || Italian scientists [[wikipedia:Giovanni Battista Grassi|Giovanni Battista Grassi]], [[wikipedia:Giuseppe Bastianelli|Giuseppe Bastianelli]] and [[wikipedia:Amico Bignami|Amico Bignami]] elucidate the entire developmental cycle ([[wikipedia:sporogony|sporogony]]) of ''[[wikipedia:Plasmodium falciparum|Plasmodium falciparum]]'', ''[[wikipedia:Plasmodium vivax|Plasmodium vivax]]'' and ''[[wikipedia:Plasmodium malariae|Plasmodium malariae]]'' in mosquito species ''[[wikipedia:Anopheles claviger|Anopheles claviger]]''.<ref name="Biodiversity of Malaria in the world"/>|| [[wikipedia:Italy|Italy]]
|-
| 1900–1907 || Program launch || In Italy, a series of laws establishes a national malaria control campaign (the first of its kind in the world).<ref>{{cite book |title=The Conquest of Malaria: Italy, 1900–1962 |first=Frank M. |last=Snowden |year=2006 |publisher=Yale University Press}}</ref>{{rp|4}} || [[wikipedia:Italy|Italy]]
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| 1902 || Award || [[wikipedia:Ronald Ross|Ronald Ross]] receives the [[wikipedia:Nobel Prize in Physiology or Medicine|Nobel Prize]] "for his work on malaria, by which he has shown how it enters the organism and thereby has laid the foundation for successful research on this disease and methods of combating it".<ref name= journey-of-scientific-discoveries/> || [[wikipedia:Sweden|Sweden]] ([[wikipedia:Stockholm|Stockholm]]
|-
| 1903 || Organization || The [[wikipedia:American Society of Tropical Medicine and Hygiene|American Society of Tropical Medicine and Hygiene]] is founded. Today it operates worldwide, yet it remains focused on developed countries. Research, health care and education are its main activities.<ref>{{cite web|title=Who We Are|publisher=[[wikipedia:American Society of Tropical Medicine and Hygiene|American Society of Tropical Medicine and Hygiene]]|url=http://www.astmh.org/about-astmh/about-us|accessdate=28 November 2016}}</ref><ref>{{cite journal|last1=Le Duc|first1=James W.|last2=DeAcetis|first2=Judy|title=Review and Assessment of the American Society of Tropical Medicine and Hygiene Travel Awards Program, 1991–2010|doi=10.4269/ajtmh.2011.11-0323|pmid=21896796|pmc=3163858|volume=85|journal=Am J Trop Med Hyg|pages=409–13}}</ref><ref>{{cite web|title=University's Stephen Higgs named tropical medicine society president-elect, honored for vaccine research|url=http://www.k-state.edu/media/newsreleases/dec14/higgsaward12214.html|publisher=K-State News|accessdate=15 December 2016}}</ref>
|data-sort-value="United States" | [[wikipedia:United States|United States]] ([[wikipedia:Philadelphia|Philadelphia]]). Serves worldwide.
|-
| 1906 || Epidemic || Of the 26,000 people working on the [[wikipedia:Panama Canal|Panama canal]], more than 21,000 are hospitalized for malaria at some time during their employment.<ref>{{cite web|title=Yellow Fever and Malaria in the Canal|url=http://ec2-184-73-198-63.compute-1.amazonaws.com/wgbh/americanexperience/features/general-article/panama-fever/|website=ec2-184-73-198-63.compute-1.amazonaws.com|accessdate=25 June 2017}}</ref> || [[wikipedia:Panama|Panama]]
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| 1908 || Science development (treatment) || German chemist Paul Rabe provides the first evidence for the structure of [[wikipedia:quinine|quinine]].<ref name="Jesuits' powder" /><ref name="Quinine">{{cite web|title=Quinine|url=https://pubs.acs.org/cen/coverstory/83/8325/8325quinine.html|publisher=[[wikipedia:Chemical & Engineering News|Chemical & Engineering News]]|accessdate=24 November 2016}}</ref>
|-
| 1910 || || The first case of malaria resistance against [[wikipedia:quinine|quinine]] is identified.<ref name="A Killer Called Malaria: The Disease That Kills Two People Every Minute">{{cite book|last1=Gyang|first1=Kofi Oteng|title=A Killer Called Malaria: The Disease That Kills Two People Every Minute|page=52|url=https://books.google.com.ar/books?id=ctMM3XTnUU0C&pg=PA52&lpg=PA52&dq=sulfadoxine%E2%80%93pyrimethamine+1967&source=bl&ots=w-wfmgL4gO&sig=Hu--GudSjzVEu87mTi395TFWJpQ&hl=en&sa=X&ved=0ahUKEwjB9avk4ffQAhWCgpAKHcf9DPMQ6AEILjAC#v=onepage&q=sulfadoxine%E2%80%93pyrimethamine%201967&f=false|accessdate=16 December 2016}}</ref><ref name="Global Defence Against the Infectious Disease Threat">{{cite book|title=Global Defence Against the Infectious Disease Threat|date=2003|publisher=[[wikipedia:World Health Organization|World Health Organization]]|isbn=9789241590297}}</ref><ref name="History of antimalarials" /> ||
|-
| 1911 || || The first transmission of malaria by [[wikipedia:blood transfusion|blood transfusion]] is described in a patient with [[wikipedia:pernicious anaemia|pernicious anaemia]].<ref>{{cite journal|title=Malaria|doi=10.1159/000197327|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928834/|accessdate=25 June 2017|pmc=2928834}}</ref> ||
|-
| 1913 || Organization || The [[wikipedia:Rockefeller Foundation|Rockefeller Foundation]] is created, and through one of its branches, the [[wikipedia:International Health Division|International Health Division]], it starts to conduct campaigns against malaria, in addition to [[wikipedia:yellow fever|yellow fever]] and [[wikipedia:hookworm|hookworm]].<ref>{{cite book|last1=Parmar|first1=Inderjeet|title=Foundations of the American Century: The Ford, Carnegie, and Rockefeller|url=https://books.google.com.ar/books?id=yR_q5sTQyloC&pg=PA40&lpg=PA40&dq=%22Rockefeller+Foundation%22+%22founded+in+1913%22&source=bl&ots=mnVNAkoSFS&sig=7BREGkxHh5Tt2n2EdDlxo8-e4pU&hl=en&sa=X&ved=0ahUKEwjDw7fjh_XQAhXEHJAKHZugBX8Q6AEIMDAE#v=onepage&q=%22Rockefeller%20Foundation%22%20%22founded%20in%201913%22&f=false|accessdate=15 December 2016}}</ref><ref>{{cite web|title=International Health Division|url=http://rockefeller100.org/exhibits/show/health/international-health-division|publisher=[[wikipedia:Rockefeller Foundation|Rockefeller Foundation]]|accessdate=15 December 2016}}</ref><ref>{{cite journal|last1=Stapleton|first1=Darwin H.|title=Lessons of history? Anti-malaria strategies of the International Health Board and the Rockefeller Foundation from the 1920s to the era of DDT.|publisher=[[wikipedia:United States National Library of Medicine|United States National Library of Medicine]]|pmc=1497608|pmid=15192908|volume=119|year=2004|journal=Public Health Rep|pages=206–15}}</ref>
| 1934 || Science development (prevention) || German scientist [[wikipedia:Hans Andersag|Hans Andersag]] discovers [[wikipedia:chloroquine|chloroquine]] at Bayer I.G. Farbenindustrie A.G. laboratories.<ref name="The History of Malaria, an Ancient Disease" />
|data-sort-value="Germany" |[[wikipedia:Germany|Germany]] ([[wikipedia:Elberfeld|Elberfeld]])
|-
| 1935–1939 || || [[wikipedia:Pyrethrin|Pyrethrin] indoor spraying operations are conducted in South Africa.<ref name="Biodiversity of Malaria in the world"/> || [[wikipedia:South Africa|South Africa]]
|-
| 1937 || Science development || Sydney James and Parr Tate discover the schizogonic form of ''[[wikipedia:Plasmodium gallinaceum|Plasmodium gallinaceum]]'' in the brains of infected chickens.<ref name="Biodiversity of Malaria in the world"/> ||
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| 1939 || Science development (prevention) || [[wikipedia:Organochloride|Organochloride]] [[wikipedia:DDT|DDT]]'s insecticidal properties are discovered by [[wikipedia:Paul Hermann Müller|Paul Hermann Müller]], who is awarded the 1948 Nobel Prize in Physiology and Medicine.<ref name="The Nobel Prize in Physiology or Medicine 1948">{{cite web|title=The Nobel Prize in Physiology or Medicine 1948|url=http://www.nobelprize.org/nobel_prizes/medicine/laureates/1948/|publisher=Nobelprize|accessdate=16 December 2016}}</ref> In the following decades, total eradication of malaria is achieved in most of the developed world due to massive agricultural application of DDT.<ref name="
| 1942 || Organization || The [[wikipedia:Office of Malaria Control in War Areas|Office of Malaria Control in War Areas]] (MCWA) is established with the purpose of limiting the impact of malaria and other vector-borne diseases (such as murine typhus) during [[wikipedia:World War II|World War II]] around military training bases in the southern United States and its territories, where malaria is still problematic at the time.<ref name="Elimination of Malaria in the United States (1947 — 1951)">{{cite web|title=Elimination of Malaria in the United States (1947 — 1951)|url=https://www.cdc.gov/malaria/about/history/elimination_us.html|publisher=[[wikipedia:Centers for Disease Control and Prevention|Centers for Disease Control and Prevention]]|accessdate=24 November 2016}}</ref><ref>{{cite book|last1=Dumenil|first1=Lynn|title=The Oxford Encyclopedia of American Social History|page=171|url=https://books.google.com.ar/books?id=N-RMAgAAQBAJ&pg=RA1-PA171&lpg=RA1-PA171&dq=%22Office+of+Malaria+Control+in+War+Areas+was%22&source=bl&ots=3Ybl59aZZx&sig=_59FVNWAf77l1SD-ykGh29mVidw&hl=en&sa=X&ved=0ahUKEwiV5LPTiPXQAhXDnJAKHV8lAw4Q6AEIIjAC#v=onepage&q=%22Office%20of%20Malaria%20Control%20in%20War%20Areas%20was%22&f=false|accessdate=15 December 2016}}</ref>
|data-sort-value="United States" | [[wikipedia:United States|United States]]
|-
| 1943 || Prevention || Indoor sprayind with [[wikipedia:DDT|DDT]] is introduced in the United States.<ref name="Biodiversity of Malaria in the world"/> || [[wikipedia:United States|United States]]
|-
| 1944 || Science development (treatment) || Chemists at [[wikipedia:Imperial Chemical Industries|Imperial Chemical Industries]] discover antimalarial [[wikipedia:proguanil|proguanil]].<ref>{{cite book|last1=Rappoport|first1=Zvi|title=The Chemistry of Anilines, Part 1|url=https://books.google.com.ar/books?id=wckakYtwttMC&pg=PA54&lpg=PA54&dq=%22proguanil%22+%221944%22&source=bl&ots=i0XQCYhf8l&sig=hIseiNIAGf_UaN7bm7ThLtGlGVI&hl=en&sa=X&ved=0ahUKEwjnqNmXuMTQAhWHIZAKHbNpDKUQ6AEIIDAB#v=onepage&q=%22proguanil%22%20%221944%22&f=false|accessdate=25 November 2016}}</ref> Proguanil is introduced for use in 1948.<ref name="A Killer Called Malaria: The Disease That Kills Two People Every Minute" /><ref name="Global Defence Against the Infectious Disease Threat"/><ref name="History of antimalarials" />
|-
| 1946 || Science development (treatment) || [[wikipedia:Camoquin|Camoquin]] is made available as new antimalarial drug. It is proved to be effective after administration of a single therapeutic dose.<ref name="Saga of Malaria Treatment" /><ref>{{cite web|title=Camoquin|url=http://www.ajtmh.org/content/s1-31/2/212.extract|publisher=[[wikipedia:American Society of Tropical Medicine and Hygiene|American Journal of Tropical Medicine and Hygiene]]|accessdate=25 November 2016}}</ref> ||
|-
| 1946–1951 || Prevention || Mass [[wikipedia:DDT|DDT]] spraying campaigns are conducted in Cyprus, Italy, Greece, Corsica, Venezuela and Guyana.<ref name="Biodiversity of Malaria in the world"/> || [[wikipedia:Cyprus|Cyprus]], [[wikipedia:Italy|Italy]], [[wikipedia:Greece|Greece]], [[wikipedia:France|France]], [[wikipedia:Venezuela|Venezuela]], [[wikipedia:Guyana|Guyana]]
|-
| 1947 || Science development || British protozoologist [[wikipedia:Henry Edward Shortt|Henry Edward Shortt]] and British parasitologist [[wikipedia:Cyril Garnham|Cyril Garnham]] show that a phase of division in the liver preceded the development of malaria parasites in the blood.<ref name="History of the discovery of the malaria parasites and their vectors"/> || United Kingdom (London)
|-
| 1947 || Program launch || In the United States, the [[wikipedia:National Malaria Eradication Program|National Malaria Eradication Program]] (NMEP) is launched in July. Prior to the launch of this program, malaria is an endemic across the United States, concentrated in the southeastern states. This federal program would successfully eradicate malaria in the United States by 1951.<ref name="who_60th"/><ref>{{cite web|url = http://www.nybooks.com/articles/archives/2011/feb/24/stopping-malaria-wrong-road/|title = Stopping Malaria: The Wrong Road|publisher = ''[[wikipedia:The New York Review of Books|The New York Review of Books]]''|last = Horton|first = Richard|authorlink = Richard Horton (editor)|date = February 24, 2011|accessdate = June 14, 2016}}</ref>
| 1949 || || The first case of malaria resistance against [[wikipedia:proguanil|proguanil]] is identified.<ref name="A Killer Called Malaria: The Disease That Kills Two People Every Minute" /><ref name="Global Defence Against the Infectious Disease Threat"/><ref name="History of antimalarials" />
|data-sort-value="Malaysia" | [[wikipedia:Malaysia|Malaysia]]<ref>{{cite book|last1=Peters|first1=Wallace|title=Antimalarial Drugs I: Biological Background, Experimental Methods, and Drug ...|url=https://books.google.com.ar/books?id=K2vwCAAAQBAJ&pg=PA435&lpg=PA435&dq=%221949%22+resistance+against+proguanil+is+identified&source=bl&ots=_1e00zYrZo&sig=_Aoj6zIqh7ylCQ9GYauRaCPbjas&hl=en&sa=X&ved=0ahUKEwj05pX8vIjRAhXDDpAKHRKwCcMQ6AEIGDAA#v=onepage&q=%221949%22%20resistance%20against%20proguanil%20is%20identified&f=false|accessdate=22 December 2016}}</ref>
|-
| 1949 || Science development || [[wikipedia:Henry Edward Shortt|Henry Edward Shortt]], [[wikipedia:Cyril Garnham|Cyril Garnham]] and co-workers describe exoerythrocytic forms of ''[[wikipedia:Plasmodium falciparum|Plasmodium falciparum]]''.<ref name="History of the discovery of the malaria parasites and their vectors"/> || United Kingdom
|-
| 1950 || Science development (treatment) || [[wikipedia:Primaquine|Primaquine]] is introduced as new antimalarial drug. It is proven to prevent relapse and sterilizes infectious sexual plasmodia.<ref>{{cite web|title=Primaquine Therapy for Malaria|url=http://cid.oxfordjournals.org/content/39/9/1336.full.pdf|publisher=[[wikipedia:Oxford Journal|Oxford Journal]]|accessdate=25 November 2016}}</ref> ||
|-
| 1952 || Science development (prevention) || Dr. [[wikipedia:Mario Pinotti|Mario Pinotti]] introduces the strategy of putting [[wikipedia:chloroquine|chloroquine]] into common cooking salt for malaria suppression, as a way of distributing the drug as a prophylactic on a wide scale. This program (using either chloroquine or [[wikipedia:pyrimethamine|pyrimethamine]]) becomes known as "Pinotti's method" and is employed in South America as well as Asia and Africa.<ref name="Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New ..." /><ref name="Interruption of Malaria Transmission by Chloroquinized Salt in Guyana">{{cite journal|title=Interruption of Malaria Transmission by Chloroquinized Salt in Guyana|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2476374/pdf/bullwho00596-0103.pdf|accessdate=25 November 2016 | pmc=2476374|pmid=4864651|volume=36|journal=Bull World Health Organ|pages=283–301 | last1 = Giglioli | first1 = G | last2 = Rutten | first2 = FJ | last3 = Ramjattan | first3 = S}}</ref> || [[wikipedia:Brazil|Brazil]]
|-
| 1952 || Science development || Antimalarial agent [[wikipedia:pyrimethamine|pyrimethamine]] is first described.<ref name="Biodiversity of Malaria in the world"/> || United States
|-
| 1954 || Science development || [[wikipedia:Henry Edward Shortt|Henry Edward Shortt]], [[wikipedia:Cyril Garnham|Cyril Garnham]] and co-workers describe exoerythrocytic forms of ''[[wikipedia:Plasmodium ovale|Plasmodium ovale]]''.<ref name="History of the discovery of the malaria parasites and their vectors"/> || United Kingdom
|-
| 1955 || Program launch || [[wikipedia:WHO|WHO]] launches the Malaria Eradication Programme. The global malaria eradication campaign is adopted by the 8th World Health Assembly and based upon the widespread use of DDT against mosquitos and of antimalarial drugs to treat malaria and eliminate the parasite in humans. Within the next decade, this program succeeds in eradicating malaria from the developed world.<ref name="who_60th">{{cite web |url=http://www.who.int/features/history/WHO_60th_anniversary_chronology.pdf |title=WHO in 60 years: a chronology of public health milestones |publisher=[[wikipedia:World Health Organization|World Health Organization]] |accessdate=April 2, 2016}}</ref><ref name="Commentary: malaria control in the 1990s." /> || Worldwide
| 1957 || || The first case of malaria resistance against [[wikipedia:chloroquine|chloroquine]] is identified.<ref name="A Killer Called Malaria: The Disease That Kills Two People Every Minute" /><ref name="Global Defence Against the Infectious Disease Threat"/><ref name="History of antimalarials" />
|data-sort-value="Thailand" | [[wikipedia:Thailand|Thailand]]<ref>{{cite journal|last1=M. Packard|first1=Randall|title=The Origins of Antimalarial-Drug Resistance|journal=[[wikipedia:The New England Journal of Medicine|The New England Journal of Medicine]]|doi=10.1056/NEJMp1403340|url=http://www.nejm.org/doi/full/10.1056/NEJMp1403340?af=R&rss=currentIssue&#t=article|accessdate=22 December 2016|volume=371|pages=397–399}}</ref>
|-
| 1957 || Study || George Macdonald develops [[wikipedia:mathematical model|mathematical models]] for malaria [[wikipedia:epidemiology|epidemiology]].<ref name="Biodiversity of Malaria in the world"/> || United Kingdom
|-
| 1955–1972 || Achievement || Bulgaria, Cyprus, Dominica, Grenada, Hungary, Italy, Jamaica, Netherlands, Poland, Romania, Saint Lucia, Spain, Taiwan, Trinidad and Tobago, United States and Venezuela are certified as malaria-free by the [[wikipedia:WHO|WHO]] within this period.<ref name="Malaria Free countries">{{cite web|title=Malaria Free countries|url=http://www.who.int/malaria/areas/elimination/overview/en/|publisher=[[wikipedia:World Health Organization|World Health Organization]]|accessdate=25 November 2016}}</ref> || Bulgaria, Cyprus, Dominica, Grenada, Hungary, Italy, Jamaica, Netherlands, Poland, Romania, Saint Lucia, Spain, Taiwan, Trinidad and Tobago, United States Venezuela
|-
| 1960 || Science development || British scientist Robert Bray demonstrates the presence The exoerythrocytic stages of ''[[wikipedia:Plasmodium malariae|Plasmodium malariae]]'' in experimentally infected chimpanzees.<ref name="History of the discovery of the malaria parasites and their vectors"/> ||
|-
| 1962 || Publication || [[wikipedia:Rachel Carson|Rachel Carson]] publishes the science book ''[[wikipedia:Silent Spring|Silent Spring]]'' which talks about the detrimental effects of the use of pesticides on the environment. The book has a massive impact in international politics, thus provoking the ban of insecticide [[wikipedia:DDT|DDT]] in many countries during the following decades. Carson continues to be criticized today by some who argue that such restrictions have caused tens of millions of needless deaths.<ref>{{cite journal|last=Baum|first=Rudy M.|date=June 4, 2007|title=Rachel Carson|journal=Chemical and Engineering News|publisher=[[wikipedia:American Chemical Society|American Chemical Society]]|volume=85|issue=23|page=5|url=http://pubs.acs.org/isubscribe/journals/cen/85/i23/html/8523editor.html}}</ref><ref>{{cite web| title=Malaria legacy|publisher=[[wikipedia:Competitive Enterprise Institute|Competitive Enterprise Institute]]|accessdate=15 December 2016|url= http://rachelwaswrong.org/malaria-legacy/}}</ref>
|data-sort-value="United States" | United States ([[wikipedia:Washington, D.C.|Washington, D.C.]]). Operates worldwide.
|-
| 1971 || Science development (prevention) ||Antimalarial [[wikipedia:mefloquine|mefloquine]] (sold under the brand names Lariam) is first synthesized at the Experimental Therapeutics Division of the Walter Reed Army Institute of Research (WRAIR). It is number 142,490 of over 500,000 chemical compounds investigated by the [[wikipedia:United States Armed Forces|United States Armed Forces]] to combat the devastating consequences of malaria in Vietnam.<ref>{{cite web|title=The Strange History of Lariam|url=http://rxisk.org/the-strange-history-of-lariam/|website=RxISK|accessdate=24 November 2016}}</ref> Mefloquine comes into use in the mid 1980s.<ref>{{cite journal|last1=Croft|first1=Ashley M|title=A lesson learnt: the rise and fall of Lariam and Halfan|doi=10.1258/jrsm.100.4.170|pmc=1847738|pmid=17404338|volume=100|date=April 2007|journal=J R Soc Med|pages=170–4}}</ref> Mefloquine is introduced for use in 1977.<ref name="A Killer Called Malaria: The Disease That Kills Two People Every Minute" /><ref name="Global Defence Against the Infectious Disease Threat"/><ref name="History of antimalarials" />
|data-sort-value="United States" | United States
|-
|data-sort-value="United Kingdom" | United Kingdom
|-
| 1987 || Science Medical development (prevention) || Colombian biochemist [[wikipedia:Manuel Elkin Patarroyo|Manuel Elkin Patarroyo]] develops the first synthetic vaccine candidate against ''[[wikipedia:plasmodium falciparum|plasmodium falciparum]]'', the parasite that causes malaria.<ref name= journey-of-scientific-discoveries/>|| Colombia|-| 1988 || Medical development (prevention) || Antimalarial drug Halfan ([[wikipedia:Halofantrine|Halofantrine]]) is first registered for treatment.<ref name="THE NEW LANDSCAPE OF NEGLECTED DISEASE DRUG DEVELOPMENT"/> ||
|-
| 1992 || Organization || [[wikipedia:Malaria Foundation International|Malaria Foundation International]] (MFI) is founded as a non-profit organization dedicated to the fight against malaria. The MFI’s goals are to support awareness, education, training, research, and leadership programs to develop and apply tools to combat the disease.<ref>{{cite web|title=Against Malaria Foundation Charity In Stone Mountain Georgia|url=http://www.charity-charities.org/Georgia-charities/StoneMountain-1661483.html|publisher=Charity Vault|accessdate=28 November 2016}}</ref><ref>{{cite book|last1=Dziedzic|first1=Nancy G.|title=Perspectives on Diseases and Disorders|publisher=Greenhaven Press/Gale Cengage Learning|url=https://books.google.com.ar/books?id=-wJaAAAAYAAJ&q=%22Malaria+Foundation+International+is+a%22&dq=%22Malaria+Foundation+International+is+a%22&hl=en&sa=X&ved=0ahUKEwjX1OjvivXQAhWECpAKHdLTC5MQ6AEIJjAA|accessdate=15 December 2016}}</ref> ||
| 1992 || Program launch || New [[wikipedia:Global Malaria Control Strategy|Global Malaria Control Strategy]] is launched. Endorsed by a ministerial conference on malaria control, it is later confirmed by the [[wikipedia:World Health Assembly|World Health Assembly]] in 1993. This new strategy is based largely upon the primary health care approach and requires flexible, cost-effective, sustainable, and decentralized programs based upon disease rather than parasite control, adapted to local conditions and responding to local needs. This approach becomes successful and has positive impact in a number of countries such as Brazil, China, Solomon Islands, Philippines, Vanuatu, Vietnam, and Thailand. Its success demonstrates that malaria can be controlled by locally and currently available tools.<ref name="Commentary: malaria control in the 1990s." /> || Worldwide
|-
| 1996 || Medical development (drug) || Antimalarial drug [[wikipedia:atovaquone|atovaquone]] is introduced. The first case of malaria resistance against atovaquone is identified in the same year.<ref name="A Killer Called Malaria: The Disease That Kills Two People Every Minute" /><ref name="Global Defence Against the Infectious Disease Threat"/><ref name="History of antimalarials" />
|data-sort-value="United Kingdom" | [[wikipedia:United Kingdom|United Kingdom]]<ref>{{cite web|title=Atovaquone/proguanil|url=http://adisinsight.springer.com/drugs/800009014|website=springer.com|accessdate=22 December 2016}}</ref>
|-
| 1996 || Medical development (drug) || Antimalarial drugs Arsumax ([[wikipedia:Artesunate|Artesunate]]) and Malarone [[wikipedia:Atovaquone/proguanil|Atovaquone/proguanil]] are first registered for treatment.<ref name="THE NEW LANDSCAPE OF NEGLECTED DISEASE DRUG DEVELOPMENT"/> ||
|-
| 1997 || Organization || [[wikipedia:Multilateral Initiative on Malaria|Multilateral Initiative on Malaria]] (MIM), an alliance of organizations that facilitates research on malaria, is established. MIM would also collaborate with the [[wikipedia:Disease Control Priorities Project|Disease Control Priorities Project]].<ref>{{cite web |url=http://www.mimalaria.org/eng/aboutmim.asp |title=About MIM |accessdate=May 19, 2016 |publisher=Multilateral Initiative on Malaria}}</ref><ref>{{cite web |url=http://www.who.int/tdr/grants/workplans/mim_bis/en/ |title=Multilateral Initiative on Malaria (MIM) |publisher=[[wikipedia:World Health Organization|World Health Organization]] |accessdate=May 19, 2016}}</ref> || [[wikipedia:Senegal|Senegal]] ([[wikipedia:Dakar|Dakar]])
| 1983 || Policy || Insecticide [[wikipedia:DDT|DDT]] is banned in [[wikipedia:Malaysia|Malaysia]].<ref name="DDTban" />
|data-sort-value="Malaysia" | [[wikipedia:Malaysia|Malaysia]]
|-
| 1984 || Prevention || Mosquito nets treated with [[wikipedia:permethrin|permethrin]] start to be used in Burkina Faso.<ref name="Biodiversity of Malaria in the world"/> || [[wikipedia:BurkinaFaso|Burkina Faso]]
|-
| 1999 || Program launch || The [[wikipedia:Research Initiative on Traditional Antimalarial Methods|Research Initiative on Traditional Antimalarial Methods]] (RITAM) is launched as a collaboration between [[wikipedia:WHO|WHO]], the [[wikipedia:Global Initiative for Traditional Systems of Health|Global Initiative for Traditional Systems of Health]] (GIFTS), the [[wikipedia:University of Oxford|University of Oxford]], and researchers and others throughout the world who are investigating or interested in the antimalarial properties of plants, with the purpose of developing or validating local herbal medicines to prevent and/or treat malaria.<ref name="Essential Medicines and Health Products Information Portal">{{cite web|title=Essential Medicines and Health Products Information Portal|url=http://apps.who.int/medicinedocs/en/d/Js2297e/7.6.html|publisher=[[wikipedia:World Health Organization|World Health Organization]]|accessdate=29 November 2016}}</ref> || [[wikipedia:Tanzania|Tanzania]] (Moshi) (inaugural meeting)
|-
| 1999 || Organization || [[wikipedia:Medicines for Malaria Venture|Medicines for Malaria Venture]] (MMV) is founded to reduce the burden of malaria by facilitating the discovery, development, and delivery of antimalarial medicines.<ref>{{cite web|url = http://www.mmv.org/about-us|title = About us|publisher = [[wikipedia:Medicines for Malaria Venture|Medicines for Malaria Venture]]|accessdate = September 2, 2016}}</ref><ref>{{cite web|url = http://www.who.int/phi/documents/medicines_for_malaria_venture.pdf|title = Medicines for Malaria Venture (MMV)|publisher = [[wikipedia:World Health Organization|World Health Organization]]|accessdate = September 2, 2016}}</ref> The [[wikipedia:Bill & Melinda Gates Foundation|Bill & Melinda Gates Foundation]] would be one of its major funders in subsequent years,<ref>{{cite web|url = http://www.gatesfoundation.org/Media-Center/Press-Releases/2005/10/Gates-Foundation-Commits-2583-Million-for-Malaria-Research|title = Gates Foundation Commits $258.3 Million for Malaria Research and Development|date = October 1, 2015|accessdate = September 2, 2016|publisher = [[wikipedia:Bill & Melinda Gates Foundation|Bill & Melinda Gates Foundation]]}}</ref> and it would partner with drug company [[wikipedia:Novartis|Novartis]].<ref>{{cite web|url = https://www.novartis.com/news/media-releases/novartis-expands-partnership-medicines-malaria-venture-develop-next-generation|website=Novartis|title = Novartis expands partnership with Medicines for Malaria Venture to develop next-generation antimalarial treatment|date = June 15, 2016|accessdate = September 2, 2016}}</ref> || [[wikipedia:Switzerland |Switzerland ]]([[wikipedia:Geneva|Geneva]])
|-
| 1999 || Medical development (drug) || Coartem ([[wikipedia:Artemether/lumefantrine|Artemether/lumefantrine]]) is registered for the treatment of malaria.<ref name="THE NEW LANDSCAPE OF NEGLECTED DISEASE DRUG DEVELOPMENT">{{cite web|title=THE NEW LANDSCAPE OF NEGLECTED DISEASE DRUG DEVELOPMENT|url=http://www.lse.ac.uk/intranet/LSEServices/communications/pressAndInformationOffice/PDF/Neglected_Diseases_05.pdf|website=lse.ac.uk|accessdate=26 April 2017}}</ref> ||
|-
| 2000 || || The African Summit on Roll Back Malaria takes place in [[wikipedia:Abuja|Abuja]], Nigeria, on April 25. Signatories committed to an intensive effort to halve mortality from malaria in Africa by 2010.<ref>{{cite web |url=http://www.rollbackmalaria.org/microsites/wmd2011/abuja_declaration_final.html |title=The Abuja Declaration and the Plan of Action |accessdate=January 19, 2017}}</ref><ref>{{cite web |url=http://www.who.int/malaria/publications/atoz/whocdsrbm200346/en/ |title=The Abuja Declaration and the plan of action. An extract from the African Summit on Roll Back Malaria |publisher=[[wikipedia:World Health Organization|World Health Organization]] |accessdate=January 19, 2017}}</ref>
| 2003 || Organization || The [[wikipedia:Malaria Consortium|Malaria Consortium]] is founded as a non-profit organization dedicated to the control of malaria.<ref>{{cite web|title=Malaria Consortium 2003-2013: a decade in communicable disease control and child health|url=http://www.malariaconsortium.org/resources/pubdev/287/malaria-consortium-2003-2013-a-decade-in-communicable-disease-control-and-child-health|publisher=[[wikipedia:Malaria Consortium|Malaria Consortium]]|accessdate=28 November 2016}}</ref><ref>{{cite web|title=Malaria Consortium – Seasonal Malaria Chemoprevention|url=http://www.givewell.org/charities/malaria-consortium|publisher=[[wikipedia:GiveWell|GiveWell]]|accessdate=15 December 2016}}</ref>
|data-sort-value="United Kingdom" | United Kingdom (London). Operates in Africa and Asia.
|-
| 2003 || Organization || [[wikipedia:Sanaria|Sanaria]] is founded as a biotechnology company. It develops vaccines protective against malaria, as well as related products for use in malaria research.<ref>{{cite web|title=WELCOME TO SANARIA|url=http://sanaria.com/|website=sanaria.com|accessdate=18 June 2017}}</ref> || United States
|-
| 2004 || Organization || [[wikipedia:Against Malaria Foundation|Against Malaria Foundation]] is set up with the aim of handling money and raising funds. Much of the funds raised by it are used to purchase bednets. [[wikipedia:GiveWell|GiveWell]], an independent charity evaluator, names AMF its top-rated charity worldwide in 2011, 2012, 2014 and 2015, and recommends to donors to donate exclusively to AMF in 2015 due to its large funding gap.<ref name="Top_Ranked_Charities">
|-
|2012 || Organization || The [[wikipedia:Malaria Eradication Scientific Alliance|Malaria Eradication Scientific Alliance]] (MESA) is formed to conduct research on malaria elimination.<ref>{{cite web|title=Iniciativa Agenda de investigación para la erradicación de la malaria (malERA)|publisher=Instituto de Salud Global Barcelona|url=http://www.isglobal.org/-/malaria-eradication-research-agenda-malera-initiative|accessdate=28 November 2016}}</ref><ref>{{cite web|title=Malaria Eradication Scientific Alliance|url=https://malariaworld.org/blog/malaria-eradication-scientific-alliance|publisher=MalariaWorld|accessdate=15 December 2016}}</ref> ||[[wikipedia:Spain|Spain]]
|-
| 2012 || Program launch || Target Malaria is launched as a not-for-profit research consortium with aims at reducing the population of malaria-transmitting mosquitoes in sub-Saharan Africa by developing and sharing technology for malaria control. Target Malaria investigates the use of genes that produce enzymes, and explores different strategies to use them in order to reduce or modify populations of [[wikipedia:Anopheles|Anopheles]] mosquitoes. Target Malaria is funded by many organizations, including [[wikipedia: Bill & Melinda Gates Foundation| Bill & Melinda Gates Foundation]], the [[wikipedia:European Commission|European Commission]], and the [[wikipedia:National Institutes of Health|National Institutes of Health]].<ref>{{cite web|title=The Extinction Invention|url=https://www.technologyreview.com/s/601213/the-extinction-invention/|website=technologyreview.com|accessdate=21 May 2017}}</ref><ref>{{cite web|title=Our Work|url=http://targetmalaria.org/our-work/|website=targetmalaria.org|accessdate=21 May 2017}}</ref> || Teams in [[wikipedia:Burkina Faso|Burkina Faso]], [[wikipedia:Mali|Mali]] and [[wikipedia:Uganda|Uganda]]
|-
| 2014 || Organization || [[wikipedia:EVIMalaR|EVIMalaR]] is conducted as a malaria research network. Funded by the [[wikipedia:European Commission|European Commission]] and involving at least 62 partners from 51 institutes.<ref>{{cite web|title=Evimalar|url=http://conservativeeurope.com/downloads/publications/aVicky%20Ford%20Research%20Oct%202012.pdf|accessdate=28 November 2016}}</ref><ref>{{cite web|last1=Waters|first1=Andrew P.|title=EVIMalaR — a model for international cooperation in scientific research|url=http://www.nature.com/nrmicro/journal/v11/n8/pdf/nrmicro3079.pdf?WT.ec_id=NRMICRO-201308|website=[[wikipedia:Nature (journal)|Nature]]|accessdate=15 December 2016}}</ref><ref>{{cite web|title=Final Report Summary - EVIMALAR (Towards the establishment of a permanent European Virtual Institute dedicated to Malaria Research (EVIMalaR).)|url=http://cordis.europa.eu/result/rcn/176027_en.html|publisher=[[wikipedia:CORDIS|CORDIS]]|accessdate=15 December 2016}}</ref> || Europe, Africa, India and Australia.
|2013–2015 || Organization || Dundee University establishes a center for development of drugs. A new anti-malaria drug is obtained.<ref>{{cite news|title=New Dundee drug centre to target killer diseases in developing world|url=http://www.bbc.com/news/uk-england-surrey-21442770|accessdate=16 December 2016|agency=[[wikipedia:BBC News|BBC News]]}}</ref><ref>{{cite news|title=New anti-malaria drug developed at Dundee University|url=http://www.bbc.com/news/uk-scotland-tayside-central-33164528|accessdate=16 December 2016|agency=[[wikipedia:BBC News|BBC News]]}}</ref>
|data-sort-value="United Kingdom" | United Kingdom ([[wikipedia:Dundee University|Dundee]])
|-
| 2015 || Scientific development || Researchers at [[wikipedia:University of California|University of California]] campuses in [[wikipedia:University of California, Irvine|Irvine]] and [[wikipedia:University of California, San Diego|San Diego]] announce they could possibly eliminate [[wikipedia:malaria|malaria]] using the CRISPR technology to start a [[wikipedia:gene drive|gene drive]] in [[wikipedia:mosquitos|mosquitos]].<ref name="CRISPR Is Rapidly Ushering in a New Era in Science">{{cite web|title=CRISPR Is Rapidly Ushering in a New Era in Science|url=https://futurism.com/crispr-is-rapidly-ushering-in-a-new-era-in-science/|website=futurism.com|accessdate=7 June 2017}}</ref> || United States
|-
| 2015 || Report || The [[wikipedia:World Health Organization|World Health Organization]] calculates 212 million cases of malaria occurring worldwide during the year, and 429,000 deaths, mostly young children.<ref>{{cite web|title=Hybrid protein offers malaria protection|url=https://www.sciencenews.org/article/hybrid-protein-offers-malaria-protection|website=sciencenews.org|accessdate=15 June 2017}}</ref> ||
|-
| 2015 || Scientific development || International research team, using [[wikipedia:DNA sequencing|DNA sequencing]], manage to assess the extent to which geographical barriers in the [[wikipedia:Amazon rainforest|Amazon rainforest]] affect genetic variation among malaria vector ''[[wikipedia:Anopheles darlingi|Anopheles darlingi]]'' populations.<ref>{{cite web|title=DNA sequencing shows divergent genomes in malaria vectors of Brazilian rainforest|url=https://www.sciencedaily.com/releases/2015/11/151102083720.htm|website=sciencedaily.com|accessdate=25 June 2017}}</ref> || [[wikipedia:Amazon basin|Amazon basin]]
|-
|}
==See also==
*[[Timeline of malaria in 2016]]
*[[Timeline of malaria in 2017]]
*[[Timeline of malaria vaccine]]
*[[Timeline of bed net distribution]]
*[[wikipedia:Timeline of cholera|Timeline of cholera]]
{{reflist|30em}}
 
{{malaria}}
{{Authority control}}
 
[[wikipedia:Category:Malaria| ]]
[[wikipedia:Category:Medicine timelines|Category:Medicine timelines]]
[[wikipedia:Category:Health-related timelines|Category:Health-related timelines]]
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