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| 2012 || || || Vaccine approval || A quadrivalent inactivated influenza vaccine is licensed in the {{w|United States}}.<ref>{{cite web|title=Influenza|url=https://www.historyofvaccines.org/content/articles/influenza|website=historyofvaccines.org|accessdate=26 April 2018}}</ref> ||
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| 2012 || November 20 || {{w|Influenza}} || Vaccine approval || "FDA approved first seasonal influenza vaccine manufactured using cell culture technology (Flucelvax, Novartis)."<ref>{{cite web |title=A First – Cell Culture Based Seasonal Influenza Vaccine Approved by the FDA |url=https://cellculturedish.com/a-first-cell-culture-based-seasonal-influenza-vaccine-approved-by-the-fda/#:~:text=On%20November%2020%2C%202012%2C%20FDA,vaccine%20in%20the%20United%20States. |website=cellculturedish.com |accessdate=3 June 2020}}</ref> ||
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| 2012 || December 12 || {{w|Influenza}} || Vaccine approval || "FDA approved quadrivalent formulation of Fluarix (inactivated influenza vaccine; GlaxoSmithKline)."<ref>{{cite web |title=Quadrivalent flu vaccines coming; companies cite good demand |url=https://www.cidrap.umn.edu/news-perspective/2013/08/quadrivalent-flu-vaccines-coming-companies-cite-good-demand |website=cidrap.umn.edu |accessdate=3 June 2020}}</ref> ||
