Difference between revisions of "Timeline of stroke"

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{{Attribute English Wikipedia|original-exists=yes}}
 
{{Attribute English Wikipedia|original-exists=yes}}
  
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This is a '''timeline of [[stroke]]''', describing especially major discoveries, developments and organizations concerning the disease.
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This is a '''timeline of [[wikipedia:stroke|stroke]]''', describing especially major discoveries, developments and organizations concerning the disease.
  
 
==Big picture==
 
==Big picture==
  
 
===Ancient times===
 
===Ancient times===
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[[Greeks|Greek]] [[physician]] [[Hippocrates]] first recognizes stroke more than 2,400 years ago, calling the condition ''[[apoplexy|apoplexia]]''. Hipocrates doesn't clarify that the condition actually happens in the [[brain]],<ref name=healthline/> instead resolving into a "stagnation of the blood, whereby all the motion and action of the spirits is taken away", and that the motion is stopped by sharp humours, or a ''[[wikt:plethora|plethora]]'' (an excess of red blood cells or bodily humours). [[Galen]] (129 AD) accepts and develops the theory of Hippocrates, believing that apoplexy is caused by anything interfering with the flow of the ''vital spirit'' to the brain. The galenic theory persists for centuries.<ref name=oxfordjournals>{{cite web|url=http://ageing.oxfordjournals.org/content/26/5/331.full.pdf|title=From apoplexy to stroke|author=|date=|accessdate=4 August 2016}}</ref>
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[[wikipedia:Greeks|Greek]] [[wikipedia:physician|physician]] [[wikipedia:Hippocrates|Hippocrates]] first recognizes stroke more than 2,400 years ago, calling the condition ''[[wikipedia:apoplexy|apoplexia]]''. Hipocrates doesn't clarify that the condition actually happens in the [[wikipedia:brain|brain]],<ref name=healthline/> instead resolving into a "stagnation of the blood, whereby all the motion and action of the spirits is taken away", and that the motion is stopped by sharp humours, or a ''[[wikipedia:wikt:plethora|plethora]]'' (an excess of red blood cells or bodily humours). [[wikipedia:Galen|Galen]] (129 AD) accepts and develops the theory of Hippocrates, believing that apoplexy is caused by anything interfering with the flow of the ''vital spirit'' to the brain. The galenic theory persists for centuries.<ref name=oxfordjournals>{{cite web|url=http://ageing.oxfordjournals.org/content/26/5/331.full.pdf|title=From apoplexy to stroke|author=|date=|accessdate=4 August 2016}}</ref>
  
 
===Early modern times===
 
===Early modern times===
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[[United Kingdom|British]] physician [[William Harvey]] (1578–1657) publishes his theory on the circulation of the blood. Others, like [[Johann Jakob Wepfer|Wepfer]] (1620–1695), still believe that apoplexy is caused by an obstruction in the path to the brain, suggesting that the brain did not receive enough "animal spirits". G.G.J. Robinson theorizes that there is a "plethora of fulness of blood", therefore bleeding is acceptable since it lessens the pressure on the "animal organs". Overall, the definition introduced by [[Hippocrates]] is still in use.<ref name=oxfordjournals/>
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[[wikipedia:United Kingdom|British]] physician [[wikipedia:William Harvey|William Harvey]] (1578–1657) publishes his theory on the circulation of the blood. Others, like [[wikipedia:Johann Jakob Wepfer|Wepfer]] (1620–1695), still believe that apoplexy is caused by an obstruction in the path to the brain, suggesting that the brain did not receive enough "animal spirits". G.G.J. Robinson theorizes that there is a "plethora of fulness of blood", therefore bleeding is acceptable since it lessens the pressure on the "animal organs". Overall, the definition introduced by [[wikipedia:Hippocrates|Hippocrates]] is still in use.<ref name=oxfordjournals/>
  
 
===1700s===
 
===1700s===
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Although remnants of old dogma persist, the foundations have been laid for apoplexy to shed some ancient traditions based on symptomatic presentation and to evolve into a [[vascular disease]] based on clinico–pathological and patho–physiological correlates. [[Théophile Bonet|Bonet]] publishes ''Sepulchretum sive Anatomica Practica'', which becomes a prominent resource for physicians during most of the 18th century.<ref name=whitaker/>
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Although remnants of old dogma persist, the foundations have been laid for apoplexy to shed some ancient traditions based on symptomatic presentation and to evolve into a [[wikipedia:vascular disease|vascular disease]] based on clinico–pathological and patho–physiological correlates. [[wikipedia:Théophile Bonet|Bonet]] publishes ''Sepulchretum sive Anatomica Practica'', which becomes a prominent resource for physicians during most of the 18th century.<ref name=whitaker/>
  
 
===1800s===
 
===1800s===
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The earliest known stroke treatments start to happen, when surgeons begin performing [[surgery]] on the [[carotid arteries]]. Surgeons begin operating to reduce cholesterol buildup and remove blockages that could then lead to a stroke.<ref name=healthline/> Reports of successful closures of injuries to the carotid arteries are documented.<ref name=nhsjs>{{cite web|url=http://nhsjs.com/2014/stroke-historical-review-and-innovative-treatments/|title=Stroke: Historical Review and Innovative Treatments|author=|date=|accessdate=5 August 2016}}</ref>
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The earliest known stroke treatments start to happen, when surgeons begin performing [[wikipedia:surgery|surgery]] on the [[wikipedia:carotid arteries|carotid arteries]]. Surgeons begin operating to reduce cholesterol buildup and remove blockages that could then lead to a stroke.<ref name=healthline/> Reports of successful closures of injuries to the carotid arteries are documented.<ref name=nhsjs>{{cite web|url=http://nhsjs.com/2014/stroke-historical-review-and-innovative-treatments/|title=Stroke: Historical Review and Innovative Treatments|author=|date=|accessdate=5 August 2016}}</ref>
  
 
===1900s===
 
===1900s===
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Early in the [[20th century]], most of the treatments for stroke patients are limited to rehabilitation after an acute stroke, and most patients are usually left with permanent and severe deficits.<ref name=nhsjs/> In the 1950s new techniques and therapies are developed to explore and modify the internal processes of [[cerebrovascular disease]].<ref name=oxfordjournals/> In the 1960s carotid endarterectomy is greatly improved but is used mostly for stroke prevention and there is still no effective treatment after an acute stroke. In the 1970s [[aspirin]] is found to be very effective in stroke prevention. In the 1980s [[cigarette]] [[smoking]] is found to be a definite risk factor for stroke, and [[smoking cessation]] programs become very important. In the 1990s [[tissue plasminogen activator]] starts to be used for treatment of [[embolic]] or [[thrombotic]] stroke.<ref name=nhsjs/>
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Early in the [[wikipedia:20th century|20th century]], most of the treatments for stroke patients are limited to rehabilitation after an acute stroke, and most patients are usually left with permanent and severe deficits.<ref name=nhsjs/> In the 1950s new techniques and therapies are developed to explore and modify the internal processes of [[wikipedia:cerebrovascular disease|cerebrovascular disease]].<ref name=oxfordjournals/> In the 1960s carotid endarterectomy is greatly improved but is used mostly for stroke prevention and there is still no effective treatment after an acute stroke. In the 1970s [[wikipedia:aspirin|aspirin]] is found to be very effective in stroke prevention. In the 1980s [[wikipedia:cigarette|cigarette]] [[wikipedia:smoking|smoking]] is found to be a definite risk factor for stroke, and [[wikipedia:smoking cessation|smoking cessation]] programs become very important. In the 1990s [[wikipedia:tissue plasminogen activator|tissue plasminogen activator]] starts to be used for treatment of [[wikipedia:embolic|embolic]] or [[wikipedia:thrombotic|thrombotic]] stroke.<ref name=nhsjs/>
  
 
===2000s===
 
===2000s===
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Today, rapid diagnosis is crucial for immediate treatment.<ref name=nhsjs/> Stroke remains the second most common cause of death worldwide, accounting for 6.7 million deaths in 2012.<ref>{{cite web|url=http://who.int/mediacentre/factsheets/fs310/en/|title=The top 10 causes of death|author=|date=|accessdate=5 July 2016}}</ref> From 1990 to 2010, the age-standardised incidence of stroke significantly decreased by 12% in [[developed country|high-income countries]], and increased by 12% in [[developing country|low-income]] and [[developing country|middle-income]] countries. In the same period, mortality rates showed a significant decrease in all countries.<ref name=Fei2013>{{cite journal |vauthors=Feigin VL, Forouzanfar MH, Krishnamurthi R, Mensah GA, Connor M, Bennett DA, Moran AE, Sacco RL, Anderson L, Truelsen T, O'Donnell M, Venketasubramanian N, Barker-Collo S, Lawes CM, Wang W, Shinohara Y, Witt E, Ezzati M, Naghavi M, Murray C | title = Global and regional burden of stroke during 1990-2010: findings from the Global Burden of Disease Study 2010 | journal = Lancet | volume = 383 | issue = 9913 | pages = 245–54 | year = 2014 | pmid = 24449944 | doi = 10.1016/S0140-6736(13)61953-4 }}</ref>
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Today, rapid diagnosis is crucial for immediate treatment.<ref name=nhsjs/> Stroke remains the second most common cause of death worldwide, accounting for 6.7 million deaths in 2012.<ref>{{cite web|url=http://who.int/mediacentre/factsheets/fs310/en/|title=The top 10 causes of death|author=|date=|accessdate=5 July 2016}}</ref> From 1990 to 2010, the age-standardised incidence of stroke significantly decreased by 12% in [[wikipedia:developed country|high-income countries]], and increased by 12% in [[wikipedia:developing country|low-income]] and [[wikipedia:developing country|middle-income]] countries. In the same period, mortality rates showed a significant decrease in all countries.<ref name=Fei2013>{{cite journal |vauthors=Feigin VL, Forouzanfar MH, Krishnamurthi R, Mensah GA, Connor M, Bennett DA, Moran AE, Sacco RL, Anderson L, Truelsen T, O'Donnell M, Venketasubramanian N, Barker-Collo S, Lawes CM, Wang W, Shinohara Y, Witt E, Ezzati M, Naghavi M, Murray C | title = Global and regional burden of stroke during 1990-2010: findings from the Global Burden of Disease Study 2010 | journal = Lancet | volume = 383 | issue = 9913 | pages = 245–54 | year = 2014 | pmid = 24449944 | doi = 10.1016/S0140-6736(13)61953-4 }}</ref>
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==Full timeline==
 
==Full timeline==
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! Year/period !! Type of event !! Event !!Location
 
! Year/period !! Type of event !! Event !!Location
 
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|460 BC–370 BC||Development||Hippocrates first recognizes stroke and calls the condition ''[[apoplexy|apoplexia]]'', which is a Greek term that stands for “struck down by violence.”<ref name=healthline>{{cite web|url=http://www.healthline.com/health/stroke/history-of-stroke#1|title=History of Stroke|author=|date=|accessdate=2 August 2016}}</ref><ref name=hopkinsmedicine/>||
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|460 BC–370 BC||Development||Hippocrates first recognizes stroke and calls the condition ''[[wikipedia:apoplexy|apoplexia]]'', which is a Greek term that stands for “struck down by violence.”<ref name=healthline>{{cite web|url=http://www.healthline.com/health/stroke/history-of-stroke#1|title=History of Stroke|author=|date=|accessdate=2 August 2016}}</ref><ref name=hopkinsmedicine/>||
 
|-
 
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|1620–1695||Discovery||[[Swiss]] pathologist [[Johann Jakob Wepfer]] discovers that something disrupts the blood supply in the brains of peopled who died from apoplexy. In some of these cases, there was massive bleeding into the brain. In others, the arteries were blocked.<ref name=healthline/><ref name=hopkinsmedicine/>||  
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|1620–1695||Discovery||[[wikipedia:Swiss|Swiss]] pathologist [[wikipedia:Johann Jakob Wepfer|Johann Jakob Wepfer]] discovers that something disrupts the blood supply in the brains of peopled who died from apoplexy. In some of these cases, there was massive bleeding into the brain. In others, the arteries were blocked.<ref name=healthline/><ref name=hopkinsmedicine/>||  
 
|-
 
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|1679||Book||[[Swiss]] physician [[Théophile Bonet]] publishes his ''Sepulchretum sive Anatomica Practica'', a work that contains 3,000 [[autopsy]] cases, included 70 cases of apoplexy, being the most extensive collection of its time.<ref name=whitaker/>||[[Geneva]], [[Switzerland]]
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|1679||Book||[[wikipedia:Swiss|Swiss]] physician [[wikipedia:Théophile Bonet|Théophile Bonet]] publishes his ''Sepulchretum sive Anatomica Practica'', a work that contains 3,000 [[wikipedia:autopsy|autopsy]] cases, included 70 cases of apoplexy, being the most extensive collection of its time.<ref name=whitaker/>||[[wikipedia:Geneva|Geneva]], [[wikipedia:Switzerland|Switzerland]]
 
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|1820||Development||[[English people|English]] [[physician]] [[John Cooke (physician)|John Cooke]] writes: {{quote|text=The term ''Apoplexia'' was employed by the Greeks, and is still used, to denote a disease in which the patient falls to the ground, often suddenly, and lies without sense or voluntary motion. Persons, instantaneously thus affected, as if struck by lightning.<ref name=whitaker>{{cite book |last=Whitaker |first=Harry |date= |title=Brain, Mind and Medicine:: Essays in Eighteenth-Century Neuroscience |url=https://books.google.com.ar/books?id=PP3VZXS7D9IC&pg=PA237&lpg=PA237&dq=%22cooke%22+%221820%22+%22apoplexia%22&source=bl&ots=mv1H1n1-wR&sig=3r4J47RqwEH5RTElcNFgIYfFB4w&hl=en&sa=X&ved=0ahUKEwjNwZ_e1ajOAhVJjZAKHU0jCf4Q6AEIGjAA#v=onepage&q=%22cooke%22%20%221820%22%20%22apoplexia%22&f=false |location= |publisher= |page=237 |isbn=}}</ref>}}
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|1820||Development||[[wikipedia:English people|English]] [[wikipedia:physician|physician]] [[wikipedia:John Cooke (physician)|John Cooke]] writes: {{quote|text=The term ''Apoplexia'' was employed by the Greeks, and is still used, to denote a disease in which the patient falls to the ground, often suddenly, and lies without sense or voluntary motion. Persons, instantaneously thus affected, as if struck by lightning.<ref name=whitaker>{{cite book |last=Whitaker |first=Harry |date= |title=Brain, Mind and Medicine:: Essays in Eighteenth-Century Neuroscience |url=https://books.google.com.ar/books?id=PP3VZXS7D9IC&pg=PA237&lpg=PA237&dq=%22cooke%22+%221820%22+%22apoplexia%22&source=bl&ots=mv1H1n1-wR&sig=3r4J47RqwEH5RTElcNFgIYfFB4w&hl=en&sa=X&ved=0ahUKEwjNwZ_e1ajOAhVJjZAKHU0jCf4Q6AEIGjAA#v=onepage&q=%22cooke%22%20%221820%22%20%22apoplexia%22&f=false |location= |publisher= |page=237 |isbn=}}</ref>}}
 
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|1927||Development||[[Portuguese people|Portuguese]] [[neurologist]] [[Egas Moniz]] successfully performs cerebral [[angiography|arteriograms]] for the study of cerebral tumors. For this work, Moniz receives the  [[Nobel Prize]] in 1949.<ref name=nhsjs/>||[[Portugal]]
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|1927||Development||[[wikipedia:Portuguese people|Portuguese]] [[wikipedia:neurologist|neurologist]] [[wikipedia:Egas Moniz|Egas Moniz]] successfully performs cerebral [[wikipedia:angiography|arteriograms]] for the study of cerebral tumors. For this work, Moniz receives the  [[wikipedia:Nobel Prize|Nobel Prize]] in 1949.<ref name=nhsjs/>||[[wikipedia:Portugal|Portugal]]
 
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|1928||Development||[[Apoplexy]] is divided into categories based on the cause of the [[blood vessel]] problem. This leads to the terms [[stroke]] or "cerebral vascular accident (CVA)."<ref name=hopkinsmedicine>{{cite web|url=http://www.hopkinsmedicine.org/healthlibrary/conditions/nervous_system_disorders/history_of_stroke_85,P00223/|title=History of Stroke|author=|date=|accessdate=3 August 2016}}</ref>||
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|1928||Development||[[wikipedia:Apoplexy|Apoplexy]] is divided into categories based on the cause of the [[wikipedia:blood vessel|blood vessel]] problem. This leads to the terms [[wikipedia:stroke|stroke]] or "cerebral vascular accident (CVA)."<ref name=hopkinsmedicine>{{cite web|url=http://www.hopkinsmedicine.org/healthlibrary/conditions/nervous_system_disorders/history_of_stroke_85,P00223/|title=History of Stroke|author=|date=|accessdate=3 August 2016}}</ref>||
 
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|1950||Organization||The [[National Institute of Neurological Disorders and Stroke]] (NINDS) is founded.<ref>{{cite web|url=http://www.ninds.nih.gov/|title=NINDS|author=|date=|accessdate=4 July 2016}}</ref>||[[Bethesda, Maryland|Bethesda]], [[Maryland]], [[U.S.A.]]
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|1950||Organization||The [[wikipedia:National Institute of Neurological Disorders and Stroke|National Institute of Neurological Disorders and Stroke]] (NINDS) is founded.<ref>{{cite web|url=http://www.ninds.nih.gov/|title=NINDS|author=|date=|accessdate=4 July 2016}}</ref>||[[wikipedia:Bethesda, Maryland|Bethesda]], [[wikipedia:Maryland|Maryland]], [[wikipedia:U.S.A.|U.S.A.]]
 
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|1954||Development||CAROTID endarterectomy is introduced as a procedure for the prevention of ischemic stroke distal to carotid-artery stenosis.<ref>{{cite journal |author=North American Symptomatic Carotid Endarterectomy Trial Collaborators |date= August 1991|title=Beneficial Effect of Carotid Endarterectomy in Symptomatic Patients with High-Grade Carotid Stenosis|url=http://www.nejm.org/doi/full/10.1056/NEJM199108153250701#t=article|journal=The New England Journal of Medicine |publisher= |volume= 325|issue= |pages= 445–453|doi=10.1056/NEJM199108153250701 |pmc= |pmid= 1852179}}</ref>||  
 
|1954||Development||CAROTID endarterectomy is introduced as a procedure for the prevention of ischemic stroke distal to carotid-artery stenosis.<ref>{{cite journal |author=North American Symptomatic Carotid Endarterectomy Trial Collaborators |date= August 1991|title=Beneficial Effect of Carotid Endarterectomy in Symptomatic Patients with High-Grade Carotid Stenosis|url=http://www.nejm.org/doi/full/10.1056/NEJM199108153250701#t=article|journal=The New England Journal of Medicine |publisher= |volume= 325|issue= |pages= 445–453|doi=10.1056/NEJM199108153250701 |pmc= |pmid= 1852179}}</ref>||  
 
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|1972||Development||[[Xingnao Kaiqiao needling method]] is developed by [[Xue-min Shi]] for the treatment of stroke, especially ischemic stroke.<ref>{{cite journal |author= |date= Apr 2015|title=Systematic review of long-term Xingnao Kaiqiao needling effcacy in ischemic stroke treatment|journal= Neural Regen Res|publisher= |volume= 10|issue= |pages= 583–8|doi=10.4103/1673-5374.155431 |pmc=4424750 |pmid= 26170818}}</ref>||[[China]]
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|1972||Development||[[wikipedia:Xingnao Kaiqiao needling method|Xingnao Kaiqiao needling method]] is developed by [[wikipedia:Xue-min Shi|Xue-min Shi]] for the treatment of stroke, especially ischemic stroke.<ref>{{cite journal |author= |date= Apr 2015|title=Systematic review of long-term Xingnao Kaiqiao needling effcacy in ischemic stroke treatment|journal= Neural Regen Res|publisher= |volume= 10|issue= |pages= 583–8|doi=10.4103/1673-5374.155431 |pmc=4424750 |pmid= 26170818}}</ref>||[[wikipedia:China|China]]
 
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|1973||Development||[[Melodic intonation therapy]] is developed as a technique in order to help stroke patients regain speaking skills.<ref>{{cite web|url=http://www.healthcentral.com/alzheimers/c/62/27130/therapy-stroke/|title=Music Therapy Helps Some Regain Speech After Stroke|author=|date=|accessdate=2 July 2016}}</ref>||Boston Veterans Affairs Hospital, [[Boston]]
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|1973||Development||[[wikipedia:Melodic intonation therapy|Melodic intonation therapy]] is developed as a technique in order to help stroke patients regain speaking skills.<ref>{{cite web|url=http://www.healthcentral.com/alzheimers/c/62/27130/therapy-stroke/|title=Music Therapy Helps Some Regain Speech After Stroke|author=|date=|accessdate=2 July 2016}}</ref>||Boston Veterans Affairs Hospital, [[wikipedia:Boston|Boston]]
 
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|1974||Development||The [[Glasgow Coma Scale]] is developed to be applied by emergency medical services to stroke or head injured patients.<ref>{{cite book |last1=Schwab |first1=Stefan  |last2=Hanley |first2=Daniel  |date= |title=Critical Care of the Stroke Patient |trans-title= |url=https://books.google.com.ar/books?id=nzaNAwAAQBAJ&pg=PA66&lpg=PA66&dq=%22stroke%22+%22developed+in+1974%22&source=bl&ots=kCB_3RhScC&sig=leunpJLNufdVt7VlEw-XAz0BVWY&hl=en&sa=X&ved=0ahUKEwjL28zip6POAhVLg5AKHfxvDnQQ6AEIGjAA#v=onepage&q=%22stroke%22%20%22developed%20in%201974%22&f=false |format= |language= |location= |publisher= |isbn= |archive-url= |archive-date= |via= |subscription= |quote= |page=66}}</ref>||[[University of Glasgow]], [[Scotland]]
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|1974||Development||The [[wikipedia:Glasgow Coma Scale|Glasgow Coma Scale]] is developed to be applied by emergency medical services to stroke or head injured patients.<ref>{{cite book |last1=Schwab |first1=Stefan  |last2=Hanley |first2=Daniel  |date= |title=Critical Care of the Stroke Patient |trans-title= |url=https://books.google.com.ar/books?id=nzaNAwAAQBAJ&pg=PA66&lpg=PA66&dq=%22stroke%22+%22developed+in+1974%22&source=bl&ots=kCB_3RhScC&sig=leunpJLNufdVt7VlEw-XAz0BVWY&hl=en&sa=X&ved=0ahUKEwjL28zip6POAhVLg5AKHfxvDnQQ6AEIGjAA#v=onepage&q=%22stroke%22%20%22developed%20in%201974%22&f=false |format= |language= |location= |publisher= |isbn= |archive-url= |archive-date= |via= |subscription= |quote= |page=66}}</ref>||[[wikipedia:University of Glasgow|University of Glasgow]], [[wikipedia:Scotland|Scotland]]
 
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|1975||Development||[[Fugl-Meyer Assessment]] is developed and later becomes the most established stroke motor measure. It is recommended for use in stroke rehabilitative trials.<ref>{{cite journal |author=Stephen J. Page,  Peter Levine, Erinn Hade |date= |title=Psychometric Properties and Administration of the Wrist/Hand Subscales of the Fugl-Meyer Assessment in Minimally-Impaired Upper Extremity Hemiparesis in Stroke|journal= Arch Phys Med Rehabil|publisher= |volume= 93|issue= |pages= 2373–6.e5|doi=10.1016/j.apmr.2012.06.017 |pmc=3494780 |pmid= 22759831 |year=2012}}</ref><ref>{{cite web|url=http://www.strokengine.ca/assess/fma/|title=Fugl-Meyer Assessment of Sensorimotor Recovery After Stroke (FMA)|author=|date=|accessdate=2 August 2016}}</ref>||
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|1975||Development||[[wikipedia:Fugl-Meyer Assessment|Fugl-Meyer Assessment]] is developed and later becomes the most established stroke motor measure. It is recommended for use in stroke rehabilitative trials.<ref>{{cite journal |author=Stephen J. Page,  Peter Levine, Erinn Hade |date= |title=Psychometric Properties and Administration of the Wrist/Hand Subscales of the Fugl-Meyer Assessment in Minimally-Impaired Upper Extremity Hemiparesis in Stroke|journal= Arch Phys Med Rehabil|publisher= |volume= 93|issue= |pages= 2373–6.e5|doi=10.1016/j.apmr.2012.06.017 |pmc=3494780 |pmid= 22759831 |year=2012}}</ref><ref>{{cite web|url=http://www.strokengine.ca/assess/fma/|title=Fugl-Meyer Assessment of Sensorimotor Recovery After Stroke (FMA)|author=|date=|accessdate=2 August 2016}}</ref>||
 
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|1976||Discovery||[[Canadian]] [[Henry J. M. Barnett|Henry Barnett]] discovers that aspirin can prevent strokes in people at high risk, and can prevent recurrences in people who have had strokes.<ref name=heartandstroke>{{cite web|url=http://www.heartandstroke.com/site/c.ikIQLcMWJtE/b.8723693/k.DD3/Solving_stroke_one_discovery_at_a_time.htm|title=How Canadian scientists are changing the future|author=|date=|accessdate=4 August 2016}}</ref>||[[Canada]]
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|1976||Discovery||[[wikipedia:Canadian|Canadian]] [[wikipedia:Henry J. M. Barnett|Henry Barnett]] discovers that aspirin can prevent strokes in people at high risk, and can prevent recurrences in people who have had strokes.<ref name=heartandstroke>{{cite web|url=http://www.heartandstroke.com/site/c.ikIQLcMWJtE/b.8723693/k.DD3/Solving_stroke_one_discovery_at_a_time.htm|title=How Canadian scientists are changing the future|author=|date=|accessdate=4 August 2016}}</ref>||[[wikipedia:Canada|Canada]]
 
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|1980-1985||Development||The [[National Institutes of Health Stroke Scale]] (NIHSS) is developed as a research tool to allow consistent reporting of neurological deficits in acute-stroke studies, particularly the early trials of [[thrombolysis]] and putative [[neuroprotection|neuroprotectants]].<ref name=NIHSS>{{cite journal |author=Jennifer K Harrison, Katherine S McArthur, and Terence J Quinn |date= |title=Assessment scales in stroke: clinimetric and clinical considerations|journal= Clin Interv Aging|publisher= |volume= 8|issue= |pages= 201–11|doi=10.2147/CIA.S32405 |pmc=3578502 |pmid= 23440256 |year=2013}}</ref>||
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|1980-1985||Development||The [[wikipedia:National Institutes of Health Stroke Scale|National Institutes of Health Stroke Scale]] (NIHSS) is developed as a research tool to allow consistent reporting of neurological deficits in acute-stroke studies, particularly the early trials of [[wikipedia:thrombolysis|thrombolysis]] and putative [[wikipedia:neuroprotection|neuroprotectants]].<ref name=NIHSS>{{cite journal |author=Jennifer K Harrison, Katherine S McArthur, and Terence J Quinn |date= |title=Assessment scales in stroke: clinimetric and clinical considerations|journal= Clin Interv Aging|publisher= |volume= 8|issue= |pages= 201–11|doi=10.2147/CIA.S32405 |pmc=3578502 |pmid= 23440256 |year=2013}}</ref>||
 
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|1989||Organization||The [[World Stroke Organization|International Stroke Society]] is established.<ref name=worldstrokecampaign/>||
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|1989||Organization||The [[wikipedia:World Stroke Organization|International Stroke Society]] is established.<ref name=worldstrokecampaign/>||
 
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|1990||Development||[[Stroke Impairment Assessment Set]] (SIAS), is developed as a comprehensive instrument to assess stroke impairment.<ref>{{cite journal |author=Liu M1, Chino N, Tuji T, Masakado Y, Hase K, Kimura A. |date= |title=Psychometric properties of the Stroke Impairment Assessment Set (SIAS)|journal= Neurorehabil Neural Repair|publisher= |volume= 16|issue= |pages= 339–51|doi= 10.1177/0888439002239279|pmc= |pmid=12462765 }}</ref>||
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|1990||Development||[[wikipedia:Stroke Impairment Assessment Set|Stroke Impairment Assessment Set]] (SIAS), is developed as a comprehensive instrument to assess stroke impairment.<ref>{{cite journal |author=Liu M1, Chino N, Tuji T, Masakado Y, Hase K, Kimura A. |date= |title=Psychometric properties of the Stroke Impairment Assessment Set (SIAS)|journal= Neurorehabil Neural Repair|publisher= |volume= 16|issue= |pages= 339–51|doi= 10.1177/0888439002239279|pmc= |pmid=12462765 }}</ref>||
 
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|-
−
|1990-1999||Development||The [[Los Angeles Prehospital Stroke Screen (LAPSS)]] is developed as a method for identifying potential stroke victims in a pre-hospital setting.<ref>{{cite book |last1=Torbey |first1=Michael |last2=Selim |first2=Magdy |date= |title=The Stroke Book |trans-title= |url=https://books.google.com.ar/books?id=-JkHnCZapLUC&pg=PA6&lpg=PA6&dq=%22Los+Angeles+Prehospital+Stroke+Screen+%28LAPSS%29%22+%22developed+in%22&source=bl&ots=bAfD4y77Fc&sig=nneedKL3azN7WHynmm0ZSDJqK-w&hl=en&sa=X&ved=0ahUKEwjMxaWD16bOAhWJD5AKHYjeCw4Q6AEIMjAE#v=onepage&q=%22Los%20Angeles%20Prehospital%20Stroke%20Screen%20%28LAPSS%29%22%20%22developed%20in%22&f=false |format= |language= |location= |publisher= |isbn= |archive-url= |archive-date= |via= |subscription= |quote= |page=6 }}</ref>||
+
|1990-1999||Development||The [[wikipedia:Los Angeles Prehospital Stroke Screen (LAPSS)|Los Angeles Prehospital Stroke Screen (LAPSS)]] is developed as a method for identifying potential stroke victims in a pre-hospital setting.<ref>{{cite book |last1=Torbey |first1=Michael |last2=Selim |first2=Magdy |date= |title=The Stroke Book |trans-title= |url=https://books.google.com.ar/books?id=-JkHnCZapLUC&pg=PA6&lpg=PA6&dq=%22Los+Angeles+Prehospital+Stroke+Screen+%28LAPSS%29%22+%22developed+in%22&source=bl&ots=bAfD4y77Fc&sig=nneedKL3azN7WHynmm0ZSDJqK-w&hl=en&sa=X&ved=0ahUKEwjMxaWD16bOAhWJD5AKHYjeCw4Q6AEIMjAE#v=onepage&q=%22Los%20Angeles%20Prehospital%20Stroke%20Screen%20%28LAPSS%29%22%20%22developed%20in%22&f=false |format= |language= |location= |publisher= |isbn= |archive-url= |archive-date= |via= |subscription= |quote= |page=6 }}</ref>||
 
|-
 
|-
−
|1994||Organization||The [[National Stroke Research Institute (Australia)]] is founded.<ref>{{cite web|url=http://www.eurohyp1.eu/the-consortium/consortium/national-stroke-research-institute-australia/|title=National Stroke Research Institute|author=|date=|accessdate=4 August 2016}}</ref>||[[Heidelberg]], [[Victoria (Australia)]]
+
|1994||Organization||The [[wikipedia:National Stroke Research Institute (Australia)|National Stroke Research Institute (Australia)]] is founded.<ref>{{cite web|url=http://www.eurohyp1.eu/the-consortium/consortium/national-stroke-research-institute-australia/|title=National Stroke Research Institute|author=|date=|accessdate=4 August 2016}}</ref>||[[wikipedia:Heidelberg|Heidelberg]], [[wikipedia:Victoria (Australia)|Victoria (Australia)]]
 
|-
 
|-
−
|1994||Development||[[Magnetic resonance imaging]] is introduced for stroke diagnosis.<ref>{{cite journal |author=Lisa R. Leffert, Caitlin R. Clancy, Brian T. Bateman, MSc, Allison S. Bryant, Elena V. Kuklina |date= |title=Hypertensive Disorders and Pregnancy-Related Stroke|journal= Obstet Gynecol|publisher= |volume= 125|issue= |pages= 124–31|doi=10.1097/AOG.0000000000000590 |pmc=4445352 |pmid= 25560114 |year=2015}}</ref>||
+
|1994||Development||[[wikipedia:Magnetic resonance imaging|Magnetic resonance imaging]] is introduced for stroke diagnosis.<ref>{{cite journal |author=Lisa R. Leffert, Caitlin R. Clancy, Brian T. Bateman, MSc, Allison S. Bryant, Elena V. Kuklina |date= |title=Hypertensive Disorders and Pregnancy-Related Stroke|journal= Obstet Gynecol|publisher= |volume= 125|issue= |pages= 124–31|doi=10.1097/AOG.0000000000000590 |pmc=4445352 |pmid= 25560114 |year=2015}}</ref>||
 
|-
 
|-
−
|1994||Organization||[[UCLA]] Stroke Center is founded.<ref>{{cite web|url=http://www.newswise.com/articles/ucla-stroke-researcher-honored-by-american-stroke-association|title=UCLA Stroke Researcher Honored by American Stroke Association |author=|date=|accessdate=4 August 2016}}</ref>||[[Los Angeles]], [[California]]
+
|1994||Organization||[[wikipedia:UCLA|UCLA]] Stroke Center is founded.<ref>{{cite web|url=http://www.newswise.com/articles/ucla-stroke-researcher-honored-by-american-stroke-association|title=UCLA Stroke Researcher Honored by American Stroke Association |author=|date=|accessdate=4 August 2016}}</ref>||[[wikipedia:Los Angeles|Los Angeles]], [[wikipedia:California|California]]
 
|-
 
|-
−
|1996||Policy||The [[Food and Drug Administration]] (FDA) first approves use of [[tissue plasminogen activator]] for treatment of stroke.<ref name=nhsjs/>||[[U.S.A.]]
+
|1996||Policy||The [[wikipedia:Food and Drug Administration|Food and Drug Administration]] (FDA) first approves use of [[wikipedia:tissue plasminogen activator|tissue plasminogen activator]] for treatment of stroke.<ref name=nhsjs/>||[[wikipedia:U.S.A.|U.S.A.]]
 
|-
 
|-
−
|1996||Organization||The [[Congressional Heart and Stroke Coalition]] is founded as a bipartisan group of senators and representatives in order to raise awareness about the prevalence and severity of cardiovascular disease and the importance of research, prevention and treatment.<ref>{{cite web|url=http://www.heart.org/HEARTORG/Advocate/Congressional-Heart-and-Stroke-Coalition_UCM_452967_Article.jsp#.V6OMKPmGMhk|title=Congressional Heart and Stroke Coalition|author=|date=|accessdate=4 August 2016}}</ref>||[[U.S.A]]
+
|1996||Organization||The [[wikipedia:Congressional Heart and Stroke Coalition|Congressional Heart and Stroke Coalition]] is founded as a bipartisan group of senators and representatives in order to raise awareness about the prevalence and severity of cardiovascular disease and the importance of research, prevention and treatment.<ref>{{cite web|url=http://www.heart.org/HEARTORG/Advocate/Congressional-Heart-and-Stroke-Coalition_UCM_452967_Article.jsp#.V6OMKPmGMhk|title=Congressional Heart and Stroke Coalition|author=|date=|accessdate=4 August 2016}}</ref>||[[wikipedia:U.S.A|U.S.A]]
 
|-
 
|-
−
|1997||Development||The [[Cincinnati Prehospital Stroke Scale]] is developed as a system used to diagnose a potential stroke in a pre-hospital setting.<ref>{{cite web|url=http://www.thenecc.org/images/2015NECCPPTSozener.pdf|title=Cincinnati Prehospital Stroke Scale|author=|date=|accessdate=3 July 2016}}</ref>||[[Cincinnati]], [[U.S.A]]
+
|1997||Development||The [[wikipedia:Cincinnati Prehospital Stroke Scale|Cincinnati Prehospital Stroke Scale]] is developed as a system used to diagnose a potential stroke in a pre-hospital setting.<ref>{{cite web|url=http://www.thenecc.org/images/2015NECCPPTSozener.pdf|title=Cincinnati Prehospital Stroke Scale|author=|date=|accessdate=3 July 2016}}</ref>||[[wikipedia:Cincinnati|Cincinnati]], [[wikipedia:U.S.A|U.S.A]]
 
|-
 
|-
−
|1998||Development||The [[FAST (stroke)|Face Arm Speech Test (FAST)]] method is developed to help detect and enhance responsiveness to stroke victim needs.<ref>{{cite journal |author=Joseph Harbison, Omar Hossain, Damian Jenkinson, John Davis, Stephen J. Louw, Gary A. Ford |date= |title=Diagnostic Accuracy of Stroke Referrals From Primary Care, Emergency Room Physicians, and Ambulance Staff Using the Face Arm Speech Test |url=http://stroke.ahajournals.org/content/34/1/71.full|journal= Stroke|publisher= |volume= 34|issue= |pages= 71–76|doi=10.1161/01.STR.0000044170.46643.5E  |pmc= |pmid= }}</ref>||[[United Kingdom]]
+
|1998||Development||The [[wikipedia:FAST (stroke)|Face Arm Speech Test (FAST)]] method is developed to help detect and enhance responsiveness to stroke victim needs.<ref>{{cite journal |author=Joseph Harbison, Omar Hossain, Damian Jenkinson, John Davis, Stephen J. Louw, Gary A. Ford |date= |title=Diagnostic Accuracy of Stroke Referrals From Primary Care, Emergency Room Physicians, and Ambulance Staff Using the Face Arm Speech Test |url=http://stroke.ahajournals.org/content/34/1/71.full|journal= Stroke|publisher= |volume= 34|issue= |pages= 71–76|doi=10.1161/01.STR.0000044170.46643.5E  |pmc= |pmid= }}</ref>||[[wikipedia:United Kingdom|United Kingdom]]
 
|-
 
|-
−
|1999||Development||''tPA'' drug, which can erase the effects of a stroke if administered within a few hours of the onset of symptoms, is approved for use.<ref name=heartandstroke/>||[[Canada]]
+
|1999||Development||''tPA'' drug, which can erase the effects of a stroke if administered within a few hours of the onset of symptoms, is approved for use.<ref name=heartandstroke/>||[[wikipedia:Canada|Canada]]
 
|-
 
|-
−
|2001||Development||[[MERCI Retriever]] is designed as a medical device to treat [[ischemic stroke]].<ref>{{cite web|url=http://www.radnet.ucla.edu/radweb/sections/endovascular/news/MERCI_Story.jsp|title=MERCI Story|author=|date=|accessdate=3 August 2016}}</ref>||[[UCLA|University of California, Los Angeles]]
+
|2001||Development||[[wikipedia:MERCI Retriever|MERCI Retriever]] is designed as a medical device to treat [[wikipedia:ischemic stroke|ischemic stroke]].<ref>{{cite web|url=http://www.radnet.ucla.edu/radweb/sections/endovascular/news/MERCI_Story.jsp|title=MERCI Story|author=|date=|accessdate=3 August 2016}}</ref>||[[wikipedia:UCLA|University of California, Los Angeles]]
 
|-
 
|-
−
|2001||Organization||The [[Canadian Stroke Network]] is founded.<ref>{{cite journal |author=Daniel S. Chow, Jason S. Hauptman, Tony T. Wong, Nestor R. Gonzalez, Neil A. Martin, Angella A. Lignelli, Michael W. Itagaki |date= |title=Changes in stroke research productivity: A global perspective|journal= Surg Neurol Int|publisher= |volume= 3|issue= |pages= 27|doi=10.4103/2152-7806.92941
+
|2001||Organization||The [[wikipedia:Canadian Stroke Network|Canadian Stroke Network]] is founded.<ref>{{cite journal |author=Daniel S. Chow, Jason S. Hauptman, Tony T. Wong, Nestor R. Gonzalez, Neil A. Martin, Angella A. Lignelli, Michael W. Itagaki |date= |title=Changes in stroke research productivity: A global perspective|journal= Surg Neurol Int|publisher= |volume= 3|issue= |pages= 27|doi=10.4103/2152-7806.92941
 
  |pmc=3307235 |pmid= 22439118 |year=2012}}</ref>||
 
  |pmc=3307235 |pmid= 22439118 |year=2012}}</ref>||
 
|-
 
|-
−
|2001||Organization||A stroke unit is established for the first time in China, in the Department of Neurology of [[Beijing Tiantan Hospital]].<ref>{{cite web|url=http://medcraveonline.com/JNSK/JNSK-03-00109.pdf|title=Beijing Tiantan Comprehensive Stroke Center|author=|date=|accessdate=3 August 2016}}</ref>||[[Beijing]]
+
|2001||Organization||A stroke unit is established for the first time in China, in the Department of Neurology of [[wikipedia:Beijing Tiantan Hospital|Beijing Tiantan Hospital]].<ref>{{cite web|url=http://medcraveonline.com/JNSK/JNSK-03-00109.pdf|title=Beijing Tiantan Comprehensive Stroke Center|author=|date=|accessdate=3 August 2016}}</ref>||[[wikipedia:Beijing|Beijing]]
 
|-
 
|-
−
|2002||Report||Stroke is found to be the sixth largest cause of [[disability]] at a worldwide level.<ref>{{cite web|url=http://www.thestar.com.my/lifestyle/health/2010/07/04/different-strokes/|title= Different strokes |author=|date=|accessdate=3 August 2016}}</ref>||
+
|2002||Report||Stroke is found to be the sixth largest cause of [[wikipedia:disability|disability]] at a worldwide level.<ref>{{cite web|url=http://www.thestar.com.my/lifestyle/health/2010/07/04/different-strokes/|title= Different strokes |author=|date=|accessdate=3 August 2016}}</ref>||
 
|-
 
|-
−
|2004||Organization||The [[World Stroke Organization|World Stroke Federation]] is established.<ref name=worldstrokecampaign/>||
+
|2004||Organization||The [[wikipedia:World Stroke Organization|World Stroke Federation]] is established.<ref name=worldstrokecampaign/>||
 
|-
 
|-
−
|2005||Development||First use of [[embryonic stem cell]]s in stroke research is performed.<ref>{{cite web|url=http://www.eurostemcell.org/factsheet/stroke-how-could-stem-cells-help|title=Stroke: how could stem cells help?|author=|date=|accessdate=3 August 2016}}</ref>||
+
|2005||Development||First use of [[wikipedia:embryonic stem cell|embryonic stem cell]]s in stroke research is performed.<ref>{{cite web|url=http://www.eurostemcell.org/factsheet/stroke-how-could-stem-cells-help|title=Stroke: how could stem cells help?|author=|date=|accessdate=3 August 2016}}</ref>||
 
|-
 
|-
−
|2006||Organization||The [[World Stroke Organization]] is established through the merger of the [[International Stroke Society]] and the [[World Stroke Federation]].<ref name=worldstrokecampaign>{{cite web|url=http://www.worldstrokecampaign.org/about-the-world-stroke-campaign/about-wso.html|title=About WSO |author=|date=|accessdate=3 August 2016}}</ref>||[[Geneva]], [[Switzerland]]
+
|2006||Organization||The [[wikipedia:World Stroke Organization|World Stroke Organization]] is established through the merger of the [[wikipedia:International Stroke Society|International Stroke Society]] and the [[wikipedia:World Stroke Federation|World Stroke Federation]].<ref name=worldstrokecampaign>{{cite web|url=http://www.worldstrokecampaign.org/about-the-world-stroke-campaign/about-wso.html|title=About WSO |author=|date=|accessdate=3 August 2016}}</ref>||[[wikipedia:Geneva|Geneva]], [[wikipedia:Switzerland|Switzerland]]
 
|-
 
|-
−
|2008||Development||The [[Kurashiki Prehospital Stroke Scale]] is developed for identifying thrombolytic candidates in acute ischemic stroke.<ref>{{cite journal |author= Jang J, Chung SP, Park I, You JS, Lee HS, Park JW, Chung TN, Chung HS, Lee HS|date= |title=The Usefulness of the Kurashiki Prehospital Stroke Scale in Identifying Thrombolytic Candidates in Acute Ischemic Stroke|journal= Yonsei Med. J.|publisher= |volume= 55|issue= |pages= 410–6|doi=10.3349/ymj.2014.55.2.410 |pmc=3936632 |pmid= 24532511 |year=2014}}</ref>||
+
|2008||Development||The [[wikipedia:Kurashiki Prehospital Stroke Scale|Kurashiki Prehospital Stroke Scale]] is developed for identifying thrombolytic candidates in acute ischemic stroke.<ref>{{cite journal |author= Jang J, Chung SP, Park I, You JS, Lee HS, Park JW, Chung TN, Chung HS, Lee HS|date= |title=The Usefulness of the Kurashiki Prehospital Stroke Scale in Identifying Thrombolytic Candidates in Acute Ischemic Stroke|journal= Yonsei Med. J.|publisher= |volume= 55|issue= |pages= 410–6|doi=10.3349/ymj.2014.55.2.410 |pmc=3936632 |pmid= 24532511 |year=2014}}</ref>||
 
|-
 
|-
−
|2016||Discovery||Immediate aspirin after mini-stroke is found to substantially reduce risk of major stroke.<ref>{{cite web|url=https://www.sciencedaily.com/releases/2016/05/160518220612.htm|title=Immediate aspirin after mini-stroke substantially reduces risk of major stroke|author=|date=|accessdate=2 August 2016}}</ref>||[[Oxford University]]
+
|2016||Discovery||Immediate aspirin after mini-stroke is found to substantially reduce risk of major stroke.<ref>{{cite web|url=https://www.sciencedaily.com/releases/2016/05/160518220612.htm|title=Immediate aspirin after mini-stroke substantially reduces risk of major stroke|author=|date=|accessdate=2 August 2016}}</ref>||[[wikipedia:Oxford University|Oxford University]]
 
|-
 
|-
 
|}
 
|}
 +
 +
== Numerical and visual data  ==
 +
 +
=== Google Scholar ===
 +
 +
The following table summarizes per-year mentions on Google Scholar as of December 12, 2021.
 +
 +
{| class="sortable wikitable"
 +
! Year
 +
! stroke
 +
|-
 +
| 1900 || 1,700
 +
|-
 +
| 1910 || 1,780
 +
|-
 +
| 1920 || 1,890
 +
|-
 +
| 1930 || 1,330
 +
|-
 +
| 1940 || 1,300
 +
|-
 +
| 1950 || 1,790
 +
|-
 +
| 1960 || 3,320
 +
|-
 +
| 1970 || 7,880
 +
|-
 +
| 1980 || 14,300
 +
|-
 +
| 1990 || 32,400
 +
|-
 +
| 2000 || 146,000
 +
|-
 +
| 2010 || 445,000
 +
|-
 +
| 2020 || 176,000
 +
|-
 +
|}
 +
 +
 +
[[File:Stroke gscho.png|thumb|center|700px]]
 +
 +
=== Google Trends ===
 +
 +
The comparative chart below shows {{w|Google Trends}} data for Stroke (Medical condition), Aneurysm (Disease), Myocardial infarction (Topic) and Seizure (Disease), from January 2004 to April 2021, when the screenshot was taken. Interest is also ranked by country and displayed on world map.<ref>{{cite web |title=Stroke, Aneurysm, Myocardial infarction and Seizure |url=https://trends.google.com/trends/explore?date=all&q=%2Fm%2F02y0js,%2Fm%2F01vpyv,%2Fm%2F0gk4g,%2Fm%2F06rhk |website=Google Trends |access-date=14 April 2021}}</ref>
 +
 +
[[File:Stroke, Aneurysm, Myocardial infarction and Seizure gt.png|thumb|center|600px]]
 +
 +
The comparative chart below shows {{w|Google Trends}} data for Ischemic Stroke (Medical condition), Brain haemorrhage  (Topic) and Transient ischemic attack (Topic), from January 2004 to April 2021, when the screenshot was taken. Interest is also ranked by country and displayed on world map.<ref>{{cite web |title=Ischemic Stroke, Brain haemorrhage and Transient ischemic attack |url=https://trends.google.com/trends/explore?date=all&q=%2Fm%2F02kb_2p,%2Fm%2F08g5q7,%2Fm%2F07s82 |website=Google Trends |access-date=18 April 2021}}</ref>
 +
 +
[[File:Ischemic Stroke, Brain haemorrhage and Transient ischemic attack gt.png|thumb|center|600px]]
 +
 +
=== Google Ngram Viewer ===
 +
 +
The comparative chart below shows {{w|Google Ngram Viewer}} data for Ischemic stroke and hemorrhagic stroke, from 1900 to 2019.<ref>{{cite web |title=Ischemic stroke and hemorrhagic stroke |url=https://books.google.com/ngrams/graph?content=Ischemic+stroke%2Chemorrhagic+stroke&year_start=1900&year_end=2019&corpus=26&smoothing=3&direct_url=t1%3B%2CIschemic%20stroke%3B%2Cc0%3B.t1%3B%2Chemorrhagic%20stroke%3B%2Cc0 |website=books.google.com |access-date=21 April 2021 |language=en}}</ref>
 +
 +
[[File:Ischemic stroke and hemorrhagic stroke ngram.png|thumb|center|700px]]
 +
 +
=== Wikipedia Views ===
 +
 +
The comparative chart below shows pageviews on desktop of the English Wikipedia articles {{w|Ischemic Stroke}}, {{w|Hemorrhagic stroke}}, and {{w|Transient ischemic attack}} from July 2015 to March 2021.<ref>{{cite web |title=Ischemic Stroke, Hemorrhagic stroke and Transient ischemic attack |url=https://wikipediaviews.org/displayviewsformultiplemonths.php?pages[0]=Ischemic+stroke&pages[1]=Hemorrhagic+stroke&pages[2]=Transient+ischemic+attack&allmonths=allmonths-api&language=en&drilldown=desktop |website=wikipediaviews.org |access-date=18 April 2021}}</ref>
 +
 +
[[File:Ischemic Stroke, Hemorrhagic stroke and Transient ischemic attack wv.png|thumb|center|450px]]
 +
  
 
==See also==
 
==See also==
−
* [[Stroke]]
+
* [[wikipedia:Stroke|Stroke]]
−
* [[Timeline of cardiovascular disease]]
+
* [[wikipedia:Timeline of cardiovascular disease|Timeline of cardiovascular disease]]
  
 
==References==
 
==References==
 
{{Reflist|30em}}
 
{{Reflist|30em}}
  
−
[[Category:Stroke]]
+
[[wikipedia:Category:Stroke|Category:Stroke]]
−
[[Category:Health-related timelines]]
+
[[wikipedia:Category:Health-related timelines|Category:Health-related timelines]]
−
[[Category:Medicine timelines]]
+
[[wikipedia:Category:Medicine timelines|Category:Medicine timelines]]

Latest revision as of 20:27, 10 April 2024

The content on this page is forked from the English Wikipedia page entitled "Timeline of stroke". The original page still exists at Timeline of stroke. The original content was released under the Creative Commons Attribution/Share-Alike License (CC-BY-SA), so this page inherits this license.

This is a timeline of stroke, describing especially major discoveries, developments and organizations concerning the disease.

Big picture

Ancient times

Greek physician Hippocrates first recognizes stroke more than 2,400 years ago, calling the condition apoplexia. Hipocrates doesn't clarify that the condition actually happens in the brain,[1] instead resolving into a "stagnation of the blood, whereby all the motion and action of the spirits is taken away", and that the motion is stopped by sharp humours, or a plethora (an excess of red blood cells or bodily humours). Galen (129 AD) accepts and develops the theory of Hippocrates, believing that apoplexy is caused by anything interfering with the flow of the vital spirit to the brain. The galenic theory persists for centuries.[2]

Early modern times

British physician William Harvey (1578–1657) publishes his theory on the circulation of the blood. Others, like Wepfer (1620–1695), still believe that apoplexy is caused by an obstruction in the path to the brain, suggesting that the brain did not receive enough "animal spirits". G.G.J. Robinson theorizes that there is a "plethora of fulness of blood", therefore bleeding is acceptable since it lessens the pressure on the "animal organs". Overall, the definition introduced by Hippocrates is still in use.[2]

1700s

Although remnants of old dogma persist, the foundations have been laid for apoplexy to shed some ancient traditions based on symptomatic presentation and to evolve into a vascular disease based on clinico–pathological and patho–physiological correlates. Bonet publishes Sepulchretum sive Anatomica Practica, which becomes a prominent resource for physicians during most of the 18th century.[3]

1800s

The earliest known stroke treatments start to happen, when surgeons begin performing surgery on the carotid arteries. Surgeons begin operating to reduce cholesterol buildup and remove blockages that could then lead to a stroke.[1] Reports of successful closures of injuries to the carotid arteries are documented.[4]

1900s

Early in the 20th century, most of the treatments for stroke patients are limited to rehabilitation after an acute stroke, and most patients are usually left with permanent and severe deficits.[4] In the 1950s new techniques and therapies are developed to explore and modify the internal processes of cerebrovascular disease.[2] In the 1960s carotid endarterectomy is greatly improved but is used mostly for stroke prevention and there is still no effective treatment after an acute stroke. In the 1970s aspirin is found to be very effective in stroke prevention. In the 1980s cigarette smoking is found to be a definite risk factor for stroke, and smoking cessation programs become very important. In the 1990s tissue plasminogen activator starts to be used for treatment of embolic or thrombotic stroke.[4]

2000s

Today, rapid diagnosis is crucial for immediate treatment.[4] Stroke remains the second most common cause of death worldwide, accounting for 6.7 million deaths in 2012.[5] From 1990 to 2010, the age-standardised incidence of stroke significantly decreased by 12% in high-income countries, and increased by 12% in low-income and middle-income countries. In the same period, mortality rates showed a significant decrease in all countries.[6]


Full timeline

Year/period Type of event Event Location
460 BC–370 BC Development Hippocrates first recognizes stroke and calls the condition apoplexia, which is a Greek term that stands for “struck down by violence.”[1][7]
1620–1695 Discovery Swiss pathologist Johann Jakob Wepfer discovers that something disrupts the blood supply in the brains of peopled who died from apoplexy. In some of these cases, there was massive bleeding into the brain. In others, the arteries were blocked.[1][7]
1679 Book Swiss physician Théophile Bonet publishes his Sepulchretum sive Anatomica Practica, a work that contains 3,000 autopsy cases, included 70 cases of apoplexy, being the most extensive collection of its time.[3] Geneva, Switzerland
1820 Development English physician John Cooke writes:
The term Apoplexia was employed by the Greeks, and is still used, to denote a disease in which the patient falls to the ground, often suddenly, and lies without sense or voluntary motion. Persons, instantaneously thus affected, as if struck by lightning.[3]
1927 Development Portuguese neurologist Egas Moniz successfully performs cerebral arteriograms for the study of cerebral tumors. For this work, Moniz receives the Nobel Prize in 1949.[4] Portugal
1928 Development Apoplexy is divided into categories based on the cause of the blood vessel problem. This leads to the terms stroke or "cerebral vascular accident (CVA)."[7]
1950 Organization The National Institute of Neurological Disorders and Stroke (NINDS) is founded.[8] Bethesda, Maryland, U.S.A.
1954 Development CAROTID endarterectomy is introduced as a procedure for the prevention of ischemic stroke distal to carotid-artery stenosis.[9]
1972 Development Xingnao Kaiqiao needling method is developed by Xue-min Shi for the treatment of stroke, especially ischemic stroke.[10] China
1973 Development Melodic intonation therapy is developed as a technique in order to help stroke patients regain speaking skills.[11] Boston Veterans Affairs Hospital, Boston
1974 Development The Glasgow Coma Scale is developed to be applied by emergency medical services to stroke or head injured patients.[12] University of Glasgow, Scotland
1975 Development Fugl-Meyer Assessment is developed and later becomes the most established stroke motor measure. It is recommended for use in stroke rehabilitative trials.[13][14]
1976 Discovery Canadian Henry Barnett discovers that aspirin can prevent strokes in people at high risk, and can prevent recurrences in people who have had strokes.[15] Canada
1980-1985 Development The National Institutes of Health Stroke Scale (NIHSS) is developed as a research tool to allow consistent reporting of neurological deficits in acute-stroke studies, particularly the early trials of thrombolysis and putative neuroprotectants.[16]
1989 Organization The International Stroke Society is established.[17]
1990 Development Stroke Impairment Assessment Set (SIAS), is developed as a comprehensive instrument to assess stroke impairment.[18]
1990-1999 Development The Los Angeles Prehospital Stroke Screen (LAPSS) is developed as a method for identifying potential stroke victims in a pre-hospital setting.[19]
1994 Organization The National Stroke Research Institute (Australia) is founded.[20] Heidelberg, Victoria (Australia)
1994 Development Magnetic resonance imaging is introduced for stroke diagnosis.[21]
1994 Organization UCLA Stroke Center is founded.[22] Los Angeles, California
1996 Policy The Food and Drug Administration (FDA) first approves use of tissue plasminogen activator for treatment of stroke.[4] U.S.A.
1996 Organization The Congressional Heart and Stroke Coalition is founded as a bipartisan group of senators and representatives in order to raise awareness about the prevalence and severity of cardiovascular disease and the importance of research, prevention and treatment.[23] U.S.A
1997 Development The Cincinnati Prehospital Stroke Scale is developed as a system used to diagnose a potential stroke in a pre-hospital setting.[24] Cincinnati, U.S.A
1998 Development The Face Arm Speech Test (FAST) method is developed to help detect and enhance responsiveness to stroke victim needs.[25] United Kingdom
1999 Development tPA drug, which can erase the effects of a stroke if administered within a few hours of the onset of symptoms, is approved for use.[15] Canada
2001 Development MERCI Retriever is designed as a medical device to treat ischemic stroke.[26] University of California, Los Angeles
2001 Organization The Canadian Stroke Network is founded.[27]
2001 Organization A stroke unit is established for the first time in China, in the Department of Neurology of Beijing Tiantan Hospital.[28] Beijing
2002 Report Stroke is found to be the sixth largest cause of disability at a worldwide level.[29]
2004 Organization The World Stroke Federation is established.[17]
2005 Development First use of embryonic stem cells in stroke research is performed.[30]
2006 Organization The World Stroke Organization is established through the merger of the International Stroke Society and the World Stroke Federation.[17] Geneva, Switzerland
2008 Development The Kurashiki Prehospital Stroke Scale is developed for identifying thrombolytic candidates in acute ischemic stroke.[31]
2016 Discovery Immediate aspirin after mini-stroke is found to substantially reduce risk of major stroke.[32] Oxford University

Numerical and visual data

Google Scholar

The following table summarizes per-year mentions on Google Scholar as of December 12, 2021.

Year stroke
1900 1,700
1910 1,780
1920 1,890
1930 1,330
1940 1,300
1950 1,790
1960 3,320
1970 7,880
1980 14,300
1990 32,400
2000 146,000
2010 445,000
2020 176,000


Stroke gscho.png

Google Trends

The comparative chart below shows Google Trends data for Stroke (Medical condition), Aneurysm (Disease), Myocardial infarction (Topic) and Seizure (Disease), from January 2004 to April 2021, when the screenshot was taken. Interest is also ranked by country and displayed on world map.[33]

Stroke, Aneurysm, Myocardial infarction and Seizure gt.png

The comparative chart below shows Google Trends data for Ischemic Stroke (Medical condition), Brain haemorrhage (Topic) and Transient ischemic attack (Topic), from January 2004 to April 2021, when the screenshot was taken. Interest is also ranked by country and displayed on world map.[34]

Ischemic Stroke, Brain haemorrhage and Transient ischemic attack gt.png

Google Ngram Viewer

The comparative chart below shows Google Ngram Viewer data for Ischemic stroke and hemorrhagic stroke, from 1900 to 2019.[35]

Ischemic stroke and hemorrhagic stroke ngram.png

Wikipedia Views

The comparative chart below shows pageviews on desktop of the English Wikipedia articles Ischemic Stroke, Hemorrhagic stroke, and Transient ischemic attack from July 2015 to March 2021.[36]

Ischemic Stroke, Hemorrhagic stroke and Transient ischemic attack wv.png


See also

References

  1. ↑ 1.0 1.1 1.2 1.3 "History of Stroke". Retrieved 2 August 2016. 
  2. ↑ 2.0 2.1 2.2 "From apoplexy to stroke" (PDF). Retrieved 4 August 2016. 
  3. ↑ 3.0 3.1 3.2 Whitaker, Harry. Brain, Mind and Medicine:: Essays in Eighteenth-Century Neuroscience. p. 237. 
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 "Stroke: Historical Review and Innovative Treatments". Retrieved 5 August 2016. 
  5. ↑ "The top 10 causes of death". Retrieved 5 July 2016. 
  6. ↑ Feigin VL, Forouzanfar MH, Krishnamurthi R, Mensah GA, Connor M, Bennett DA, Moran AE, Sacco RL, Anderson L, Truelsen T, O'Donnell M, Venketasubramanian N, Barker-Collo S, Lawes CM, Wang W, Shinohara Y, Witt E, Ezzati M, Naghavi M, Murray C (2014). "Global and regional burden of stroke during 1990-2010: findings from the Global Burden of Disease Study 2010". Lancet. 383 (9913): 245–54. PMID 24449944. doi:10.1016/S0140-6736(13)61953-4. 
  7. ↑ 7.0 7.1 7.2 "History of Stroke". Retrieved 3 August 2016. 
  8. ↑ "NINDS". Retrieved 4 July 2016. 
  9. ↑ North American Symptomatic Carotid Endarterectomy Trial Collaborators (August 1991). "Beneficial Effect of Carotid Endarterectomy in Symptomatic Patients with High-Grade Carotid Stenosis". The New England Journal of Medicine. 325: 445–453. PMID 1852179. doi:10.1056/NEJM199108153250701. 
  10. ↑ "Systematic review of long-term Xingnao Kaiqiao needling effcacy in ischemic stroke treatment". Neural Regen Res. 10: 583–8. Apr 2015. PMC 4424750Freely accessible. PMID 26170818. doi:10.4103/1673-5374.155431. 
  11. ↑ "Music Therapy Helps Some Regain Speech After Stroke". Retrieved 2 July 2016. 
  12. ↑ Schwab, Stefan; Hanley, Daniel. Critical Care of the Stroke Patient. p. 66. 
  13. ↑ Stephen J. Page, Peter Levine, Erinn Hade (2012). "Psychometric Properties and Administration of the Wrist/Hand Subscales of the Fugl-Meyer Assessment in Minimally-Impaired Upper Extremity Hemiparesis in Stroke". Arch Phys Med Rehabil. 93: 2373–6.e5. PMC 3494780Freely accessible. PMID 22759831. doi:10.1016/j.apmr.2012.06.017. 
  14. ↑ "Fugl-Meyer Assessment of Sensorimotor Recovery After Stroke (FMA)". Retrieved 2 August 2016. 
  15. ↑ 15.0 15.1 "How Canadian scientists are changing the future". Retrieved 4 August 2016. 
  16. ↑ Jennifer K Harrison, Katherine S McArthur, and Terence J Quinn (2013). "Assessment scales in stroke: clinimetric and clinical considerations". Clin Interv Aging. 8: 201–11. PMC 3578502Freely accessible. PMID 23440256. doi:10.2147/CIA.S32405. 
  17. ↑ 17.0 17.1 17.2 "About WSO". Retrieved 3 August 2016. 
  18. ↑ Liu M1, Chino N, Tuji T, Masakado Y, Hase K, Kimura A. "Psychometric properties of the Stroke Impairment Assessment Set (SIAS)". Neurorehabil Neural Repair. 16: 339–51. PMID 12462765. doi:10.1177/0888439002239279. 
  19. ↑ Torbey, Michael; Selim, Magdy. The Stroke Book. p. 6. 
  20. ↑ "National Stroke Research Institute". Retrieved 4 August 2016. 
  21. ↑ Lisa R. Leffert, Caitlin R. Clancy, Brian T. Bateman, MSc, Allison S. Bryant, Elena V. Kuklina (2015). "Hypertensive Disorders and Pregnancy-Related Stroke". Obstet Gynecol. 125: 124–31. PMC 4445352Freely accessible. PMID 25560114. doi:10.1097/AOG.0000000000000590. 
  22. ↑ "UCLA Stroke Researcher Honored by American Stroke Association". Retrieved 4 August 2016. 
  23. ↑ "Congressional Heart and Stroke Coalition". Retrieved 4 August 2016. 
  24. ↑ "Cincinnati Prehospital Stroke Scale" (PDF). Retrieved 3 July 2016. 
  25. ↑ Joseph Harbison, Omar Hossain, Damian Jenkinson, John Davis, Stephen J. Louw, Gary A. Ford. "Diagnostic Accuracy of Stroke Referrals From Primary Care, Emergency Room Physicians, and Ambulance Staff Using the Face Arm Speech Test". Stroke. 34: 71–76. doi:10.1161/01.STR.0000044170.46643.5E. 
  26. ↑ "MERCI Story". Retrieved 3 August 2016. 
  27. ↑ Daniel S. Chow, Jason S. Hauptman, Tony T. Wong, Nestor R. Gonzalez, Neil A. Martin, Angella A. Lignelli, Michael W. Itagaki (2012). "Changes in stroke research productivity: A global perspective". Surg Neurol Int. 3: 27. PMC 3307235Freely accessible. PMID 22439118. doi:10.4103/2152-7806.92941. 
  28. ↑ "Beijing Tiantan Comprehensive Stroke Center" (PDF). Retrieved 3 August 2016. 
  29. ↑ "Different strokes". Retrieved 3 August 2016. 
  30. ↑ "Stroke: how could stem cells help?". Retrieved 3 August 2016. 
  31. ↑ Jang J, Chung SP, Park I, You JS, Lee HS, Park JW, Chung TN, Chung HS, Lee HS (2014). "The Usefulness of the Kurashiki Prehospital Stroke Scale in Identifying Thrombolytic Candidates in Acute Ischemic Stroke". Yonsei Med. J. 55: 410–6. PMC 3936632Freely accessible. PMID 24532511. doi:10.3349/ymj.2014.55.2.410. 
  32. ↑ "Immediate aspirin after mini-stroke substantially reduces risk of major stroke". Retrieved 2 August 2016. 
  33. ↑ "Stroke, Aneurysm, Myocardial infarction and Seizure". Google Trends. Retrieved 14 April 2021. 
  34. ↑ "Ischemic Stroke, Brain haemorrhage and Transient ischemic attack". Google Trends. Retrieved 18 April 2021. 
  35. ↑ "Ischemic stroke and hemorrhagic stroke". books.google.com. Retrieved 21 April 2021. 
  36. ↑ "Ischemic Stroke, Hemorrhagic stroke and Transient ischemic attack". wikipediaviews.org. Retrieved 18 April 2021. 

Category:Stroke Category:Health-related timelines Category:Medicine timelines

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