Difference between revisions of "Timeline of psychoactive drugs"
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| 1841 || || French psychiatrist {{w|Jacques-Joseph Moreau}} uses {{w|hashish}} in treatment of mental patients at the {{w|Bicêtre Hospital}}.<ref name="Timeline of Events in the History of Drugs"/><ref>{{cite book|last1=Emboden|first1=William A.|title=Narcotic plants|url=https://books.google.com.ar/books?id=ecNqAAAAMAAJ&q=%22in+1841%22+%22hashish%22&dq=%22in+1841%22+%22hashish%22&hl=en&sa=X&ved=0ahUKEwid9ODk77fZAhVFg5AKHbrnByw4ChDoAQgwMAI}}</ref><ref>{{cite book|last1=Booth|first1=Martin|title=Cannabis: A History|url=https://books.google.com.ar/books?id=ecITBwAAQBAJ&pg=PA82&dq=%22in+1841%22+%22hashish%22&hl=en&sa=X&ved=0ahUKEwjgncW177fZAhUGiZAKHQqYCCYQ6AEIJzAA#v=onepage&q=%22in%201841%22%20%22hashish%22&f=false}}</ref><ref>{{cite book|last1=Boon|first1=Marcus|title=The Road of Excess: A History of Writers on Drugs|url=https://books.google.com.ar/books?id=E376kG-lqN8C&pg=PA138&dq=%22in+1841%22+%22hashish%22&hl=en&sa=X&ved=0ahUKEwjgncW177fZAhUGiZAKHQqYCCYQ6AEIMjAC#v=onepage&q=%22in%201841%22%20%22hashish%22&f=false}}</ref> || {{w|France}} | | 1841 || || French psychiatrist {{w|Jacques-Joseph Moreau}} uses {{w|hashish}} in treatment of mental patients at the {{w|Bicêtre Hospital}}.<ref name="Timeline of Events in the History of Drugs"/><ref>{{cite book|last1=Emboden|first1=William A.|title=Narcotic plants|url=https://books.google.com.ar/books?id=ecNqAAAAMAAJ&q=%22in+1841%22+%22hashish%22&dq=%22in+1841%22+%22hashish%22&hl=en&sa=X&ved=0ahUKEwid9ODk77fZAhVFg5AKHbrnByw4ChDoAQgwMAI}}</ref><ref>{{cite book|last1=Booth|first1=Martin|title=Cannabis: A History|url=https://books.google.com.ar/books?id=ecITBwAAQBAJ&pg=PA82&dq=%22in+1841%22+%22hashish%22&hl=en&sa=X&ved=0ahUKEwjgncW177fZAhUGiZAKHQqYCCYQ6AEIJzAA#v=onepage&q=%22in%201841%22%20%22hashish%22&f=false}}</ref><ref>{{cite book|last1=Boon|first1=Marcus|title=The Road of Excess: A History of Writers on Drugs|url=https://books.google.com.ar/books?id=E376kG-lqN8C&pg=PA138&dq=%22in+1841%22+%22hashish%22&hl=en&sa=X&ved=0ahUKEwjgncW177fZAhUGiZAKHQqYCCYQ6AEIMjAC#v=onepage&q=%22in%201841%22%20%22hashish%22&f=false}}</ref> || {{w|France}} | ||
| + | |- | ||
| + | | 1841 || Discovery || Russian chemist Alexander Voskresensky first discovers {{w|theobromine}}.<ref>{{cite book|last1=von Bibra,|first1=Baron Ernst|last2=Ott|first2=Jonathan|title=Plant Intoxicants: A Classic Text on the Use of Mind-Altering Plants|url=https://books.google.com.ar/books?id=EWqhC4djXSQC&pg=PA67&lpg=PA67&dq=Theobromine+1841&source=web&ots=PZISTwSSiB&sig=wlF1zok-GMU1xRakPPmBi_7Qagw&hl=en&sa=X&oi=book_result&ct=result&redir_esc=y#v=onepage&q=Theobromine%201841&f=false}}</ref> || | ||
|- | |- | ||
| 1842 || || French physiologist {{w|Claude Bernard}} discovers that the arrow poison curare acts at the neuromuscular junction to interrupt the stimulation of muscle by nerve impulses.<ref name="A brief history of pharmacology"/> || | | 1842 || || French physiologist {{w|Claude Bernard}} discovers that the arrow poison curare acts at the neuromuscular junction to interrupt the stimulation of muscle by nerve impulses.<ref name="A brief history of pharmacology"/> || | ||
|- | |- | ||
| − | | 1844 || || Cocaine is isolated in its pure form.<ref name="Timeline of Events in the History of Drugs"/> || | + | | 1844 || Scientific development || Cocaine is isolated in its pure form.<ref name="Timeline of Events in the History of Drugs"/> || |
|- | |- | ||
| 1850s || Introduction || {{w|Opiate}}s are injected to treate {{w|neuralgia}}.<ref name="Painkillers: History, Science, and Issues"/> || | | 1850s || Introduction || {{w|Opiate}}s are injected to treate {{w|neuralgia}}.<ref name="Painkillers: History, Science, and Issues"/> || | ||
|- | |- | ||
| − | | 1864 || || {{w|Adolf von Baeyer}} in Ghent synthesizes barbituric acid, the first barbiturate.<ref name="Timeline of Events in the History of Drugs"/> || {{w|Belgium}} | + | | 1864 || Scientific development || {{w|Adolf von Baeyer}} in Ghent synthesizes barbituric acid, the first barbiturate.<ref name="Timeline of Events in the History of Drugs"/> || {{w|Belgium}} |
|- | |- | ||
| 1869 || || The first synthetic drug, {{w|chloral hydrate}}, is discovered and introduced as a sedative-hypnotic.<ref>{{cite journal|last1=Jones|first1=AW|title=Early drug discovery and the rise of pharmaceutical chemistry|doi=10.1002/dta.301|pmid=21698778|url=https://www.ncbi.nlm.nih.gov/pubmed/21698778}}</ref> || | | 1869 || || The first synthetic drug, {{w|chloral hydrate}}, is discovered and introduced as a sedative-hypnotic.<ref>{{cite journal|last1=Jones|first1=AW|title=Early drug discovery and the rise of pharmaceutical chemistry|doi=10.1002/dta.301|pmid=21698778|url=https://www.ncbi.nlm.nih.gov/pubmed/21698778}}</ref> || | ||
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| 1912 || || {{w|Phenobarbital}} is introduced into therapeutics under the trade name of Luminal.<ref name="Timeline of Events in the History of Drugs"/> || | | 1912 || || {{w|Phenobarbital}} is introduced into therapeutics under the trade name of Luminal.<ref name="Timeline of Events in the History of Drugs"/> || | ||
| + | |- | ||
| + | | 1958 || || {{w|Denatonium}} is discovered during research on local anesthetics by {{w|MacFarlan Smith}} of {{w|Edinburgh}}, {{w|Scotland}}, and registered under the trademark ''Bitrex''.<ref>{{cite web|title=DENATONIUM|url=https://www.edinformatics.com/math_science/science_of_cooking/denatorium.htm|website=edinformatics.com|accessdate=9 March 2018}}</ref> || {{w|United Kingdom}} | ||
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Revision as of 10:12, 9 March 2018
This is a timeline of psychoactive drugs, focusing on their medical use in anesthesia, pain management, and mental disorders.
Contents
Big picture
| Time period | Development summary |
|---|---|
| Ancient times | The use of natural extracts for medicinal purposes goes back thousands of years.[1] Most likely discovered through a combination of trial and error, early medicines often had as much religious and spiritual significance as they did healing importance. Plants were the basis of the ancient medicines, and were complemented with minerals and animal substances. Often the same plants and herbs were used for similar diseases among different civilizations, even though they were discovered separately.[2] |
| 5th–15th century | During the Middle Ages, opium continues to be used and abused in several societies.[3] However, treatment of disease through development of new herbal remedies may have been very difficult in an environment where the prevailing attitude is that disease is God’s punishment for sin. Practitioners of herbal remedies would often be seen as heretics. Medical progress is very weak due to the prevailing unscientific opinion.[2] |
| 14th–17th century | During the Renaissance, the development of medicinal remedies in Europe is reborn. In the 15th century, Italian anatomists use opium to sedate prisoners before performing dissections on them.[3] Paracelsus brings opium into the European pharmacopoeia in the early 16th century, and also develops the modern concept of dose dependency for drug action and toxicity.[2] |
| 18th century | Opium is often used not only as a painkiller, but also as a stimulant or nervous sedative.[3] |
Full timeline
| Year | Event type | Details | Geographical location |
|---|---|---|---|
| 50,000 years ago | Neanderthal burial site in Iraq is found to contain remains of the herbal stimulant ephedra. Palaeolithic cave art across Europe and Africa suggests artists had experience of hallucinogens (or possibly migraines).[4] | Iraq | |
| c.10,000 BC | Earliest agriculture. Some evidence that the first crops include psychoactive plants such as mandrake, tobacco, coffee and cannabis.[4] | ||
| c.7000 BC | Betel seeds, chewed for their stimulant effects, are found in archaeological sites in Asia.[4][5] | ||
| c.6000 BC | Tobacco is cultivated and used by native South Americans.[5][4] | ||
| c.5000 BC | The Sumerians already make use of opium.[6] | ||
| c.4200 BC | Opium poppy seed pods are found in a burial site at Albuñol, Spain.[4][5] | Spain | |
| c.4000 BC | Wine and beer are being produced in Egypt and Sumeria.[4] | Egypt, Near East, Middle East | |
| c.3500 BC | The description of a brewery in an an Egyptian papyrus is the earliest historical record of the production of alcohol.[6] | ||
| c.3000 BC | The use of tea in China originates around this time.[6] | China | |
| c.3000 BC | Cannabis is cultivated in China and other regions of Asia; evidence of cannabis smoking is also found in eastern Europe.[6][5] | ||
| c.2500 BC | Early historical evidence of the eating of poppy seeds among the Lake Dwellers on Switzerland.[6] | Switzerland | |
| c.2000 BC | Coca residues are found in the hair of Andean mummies.[4][5] | ||
| c.1000 BC | Central Americans erect temples to mushroom gods.[5] | ||
| 800 BC | Distilled spirits and rice beer originate in India.[4][7][8] | India | |
| 1493 | Introduction | Columbus and his crew introduce tobacco in Europe.[6] | Europe |
| c.1525 | Swiss physician Paracelsus introduces laudanum, or tincture of opium, into the practice of medicine.[9][6] | Switzerland | |
| 1551 | Publication | English physician William Turner advocates the use of the opium poppy in his herbal treatise, the first one to be published in the English language. | United Kingdom |
| 1625–1665 | Introduction | In response to outbreaks of plague in London, mithridatium, based on a complex formulation including opium, is one of the main recommended remedies.[3] | United Kingdom |
| 1750–1799 | Introduction | English botanist William Withering introduces the digitalis, an extract from the plant foxglove, for treatment of cardiac problems.[10] | United Kingdom |
| 1753 | Publication | Swedish botanist Carl Linnaeus publishes his Species Plantarum, which first classifies the opium poppy as Papaver Somniferum, which literally means "sleep–inducing".[3] | Sweden |
| 1760s | Introduction | English physician Thomas Sydenham popularizes laudanum.[11] | United Kingdom |
| 1762 | Introduction | English physician Thomas Dover introduces his prescription for a diaphoretic powder, which he recommends mainly for the treatment of gout. Soon named “Dover’s powder”, this compound becomes the most widely used opium preparation during the next 150 years.[6][3] | United Kingdom |
| 1806 | Introduction | German pharmacist Friedrich Sertürner manages to extract morphine from opium, launching the first generation of true drugs.[2][6] | Germany |
| 1840s | Introduction | Lithium is first used to treat bladder stones and gout.[12] | |
| 1841 | French psychiatrist Jacques-Joseph Moreau uses hashish in treatment of mental patients at the Bicêtre Hospital.[6][13][14][15] | France | |
| 1841 | Discovery | Russian chemist Alexander Voskresensky first discovers theobromine.[16] | |
| 1842 | French physiologist Claude Bernard discovers that the arrow poison curare acts at the neuromuscular junction to interrupt the stimulation of muscle by nerve impulses.[17] | ||
| 1844 | Scientific development | Cocaine is isolated in its pure form.[6] | |
| 1850s | Introduction | Opiates are injected to treate neuralgia.[3] | |
| 1864 | Scientific development | Adolf von Baeyer in Ghent synthesizes barbituric acid, the first barbiturate.[6] | Belgium |
| 1869 | The first synthetic drug, chloral hydrate, is discovered and introduced as a sedative-hypnotic.[18] | ||
| 1869 | Treatment | English physician Clifford Allbutt recommends the injection of morphine to treat heart disease.[3][19] | United Kingdom |
| 1875 | Treatment | Dr. Anderson recommends the injection of morphine to treat asthma.[3] | |
| 1884 | Cocaine is first introduced as a local anesthetic.[12] | ||
| 1886 | The recipe for Coca-Cola is patented, including coca leaves and caffeine-rich kola nuts. in 1906 Coca leaves would be removed from the recipe for Coca-Cola.[4] | United States | |
| 1887 | Amphetamine is synthesized in Germany.[4] | Germany | |
| 1898 | Diacetylmorphine (heroin) is synthesized in Germany.[6] | Germany | |
| 1905 | German chemist Alfred Einhorn discovers the injectable local anesthetic procaine, which would become Novocain.[12] | ||
| 1912 | 3,4-Methylenedioxymethamphetamine (MDMA) is synthesised by pharmaceutical firm Merck.[4] | ||
| 1912 | Phenobarbital is introduced into therapeutics under the trade name of Luminal.[6] | ||
| 1958 | Denatonium is discovered during research on local anesthetics by MacFarlan Smith of Edinburgh, Scotland, and registered under the trademark Bitrex.[20] | United Kingdom |
Meta information on the timeline
How the timeline was built
The initial version of the timeline was written by User:Sebastian.
Funding information for this timeline is available.
What the timeline is still missing
Timeline update strategy
See also
External links
References
- ↑ Cite error: Invalid
<ref>tag; no text was provided for refs namedA_SHORT_HISTORY_OF_DRUG_DISCOVERY - ↑ 2.0 2.1 2.2 2.3 "The History of Therapeutic Drug Development". twistbioscience.com. Retrieved 19 February 2018.
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 Stolberg, Victor B. Painkillers: History, Science, and Issues.
- ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 "Timeline: Drugs and Alcohol". newscientist.com. Retrieved 20 February 2018.
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Plant, Martin. Drug Nation: Patterns, Problems, Panics & Policies.
- ↑ 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 6.13 "Timeline of Events in the History of Drugs". inpud.wordpress.com. Retrieved 20 February 2018.
- ↑ Maiya, Harish. The King of Good Times.
- ↑ Dasgupta, Amitava; Langman, Loralie J. Pharmacogenomics of Alcohol and Drugs of Abuse.
- ↑ Deming, David. Science and Technology in World History, Volume 3: The Black Death, the Renaissance, the Reformation and the Scientific Revolution.
- ↑ Cite error: Invalid
<ref>tag; no text was provided for refs namedHISTORY_OF_DRUG_DISCOVERY_AND_DEVELOPMENT - ↑ Kamieński, Łukasz. Shooting Up: A Short History of Drugs and War.
- ↑ 12.0 12.1 12.2 GELMAN, LAUREN. "The Accidental History of 10 Common Drugs". rd.com. Retrieved 20 February 2018.
- ↑ Emboden, William A. Narcotic plants.
- ↑ Booth, Martin. Cannabis: A History.
- ↑ Boon, Marcus. The Road of Excess: A History of Writers on Drugs.
- ↑ von Bibra,, Baron Ernst; Ott, Jonathan. Plant Intoxicants: A Classic Text on the Use of Mind-Altering Plants.
- ↑ Cite error: Invalid
<ref>tag; no text was provided for refs namedA_brief_history_of_pharmacology - ↑ Jones, AW. "Early drug discovery and the rise of pharmaceutical chemistry". PMID 21698778. doi:10.1002/dta.301.
- ↑ Padwa, Howard. Social Poison: The Culture and Politics of Opiate Control in Britain and France, 1821--1926.
- ↑ "DENATONIUM". edinformatics.com. Retrieved 9 March 2018.
