Difference between revisions of "Talk:Timeline of brain preservation"

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m (Mati Roy moved page Talk:Timeline of cryonics to Talk:Timeline of brain preservation: the article doesn't only discuss cryonics, but brain preservations in general)
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== Papers ==
 
== Papers ==
 
This section was removed as it doesn't meaningfully track the progress of cryonics.
 
This section was removed as it doesn't meaningfully track the progress of cryonics.
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The following graph is an attempt to track the progress of cryopreservation techniques by tracking the biggest mass that was successfully cryopreserved, and is based on the table that follows it.<ref>{{Citation|last=RomanPlusPlus|title=SPTCR: curated repository of scientific papers on cryonics: RomanPlusPlus/scientific-progress-towards-cryonics|date=2019-01-11|url=https://github.com/RomanPlusPlus/scientific-progress-towards-cryonics|access-date=2019-01-23}}</ref>
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[[File:biggest_mass_cryopreserve.png|600px]]
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{| class="sortable wikitable"
 
{| class="sortable wikitable"
! Year !! Taxon !! tissue, organ or whole body? !! Approx. mass, kg !! Lowest temperature (°C) after which a successful reanimation was achieved !! Healthy brain activity / behavior after reanimation? !! Reference
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! Year !! Taxon !! tissue, organ or whole body? !! Approx. mass, kg !! Lowest temperature (°C) after which a successful reanimation was achieved !! Healthy brain activity/behavior after reanimation? !! Reference
  
 
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Revision as of 00:19, 15 February 2019

Papers

This section was removed as it doesn't meaningfully track the progress of cryonics.

The following graph is an attempt to track the progress of cryopreservation techniques by tracking the biggest mass that was successfully cryopreserved, and is based on the table that follows it.[1]

Biggest mass cryopreserve.png


Year Taxon tissue, organ or whole body? Approx. mass, kg Lowest temperature (°C) after which a successful reanimation was achieved Healthy brain activity/behavior after reanimation? Reference
1876 Guinea pig (C. porcellus) whole 1 18 Unknown Bernard, 1876
1881 Marmots (Marmota) whole 3 0 Likely yes (adapted to hibernation) Horvath, 1881
1912 Schreibers' bat (M. schreibersii) whole 0.02 -4 Unknown Bachmetiev, 1912
1933 Bats (Chiroptera) whole 0.004 0 Unknown Eisentraut, 1933
1949 Human: unnamed donors red blood cells 9E-14 -79 Irrelevant - no brain tissue Smith et al, 1949
1949 Human: unnamed donors spermatozoa 3E-15 -79 Irrelevant - no brain tissue Polge et al, 1949
1950 Tardigrades (Tardigrada) whole 2E-11 -272 Unknown Becquerel, 1950
1950 Mammals (Mammalia) skin <0,1 -79 Irrelevant - no brain tissue Kreyberg, Hanssen, 1950 (via Fahy, 1980)
1951 Human: unnamed 23yo woman whole 60 16 Yes (no abnormalities observed) Laufmann, 1951
1951 Brown rat (R. norvegicus) whole 0.2 0 Unknown Andjus, 1951
1952 European rabbit (O. cuniculus) skin <0,1 -150 Irrelevant - no brain tissue Billingham, Medawar, 1952
1953 Primate: lemur C. major whole 0.4 19 Unknown Bourliere et al, 1953
1955 House mouse (M. musculus) spleen 0.0001 -79 Irrelevant - no brain tissue Barnes,Loutit, 1955
1955 Brown rat (R. norvegicus) whole 0.2 -3 Unknown Andjus, 1955
1956 Brown rat (R. norvegicus) whole 0.2 0 Yes (no abnormalities observed) Andjus, 1956
1956 Golden hamster (M. auratus) whole 0.1 -1 Yes (no abnormalities observed) Lovelock, Smith, 1956
1957 Mammals (Mammalia) ovarian tissue 0.0000000005 -79 Irrelevant - no brain tissue Parkes, 1957 (via Fahy, 1980)
1957 Primate: some Simiiformes whole 4 11 Yes (habits preserved, no abnormalities) Niazi and Lewis, 1957
1957 Brown rat (R. norvegicus) sup. сervic. ganglion 0.0000005 -79 full recovery of synaptic function Pascoe, Parkes, 1957
1958 Mammals (Mammalia) renal tissue <0,1 -79 Irrelevant - no brain tissue Vieuchange, 1958 (via Fahy, 1980)
1958 Leisler's bat (N. leisleri) whole 0.01 -7 Unknown Kalabukhov, 1958
1959 Mammals (Mammalia) thyroid tissue <0,1 -79 Irrelevant - no brain tissue Parkes, 1959 (via Fahy, 1980)
1959 Golden hamster (M. auratus) whole 0.1 -5 Unknown Andjus, 1959
1959 European rabbit (O. cuniculus) whole 2 14 Unknown Andjus, 1959
1959 Human: brain surgery patients whole 60 28 Likely yes (a standard praxis in 2018) Soleimanpour et al, 2014
1961 Mammals (Mammalia) adrenal cortex <0,1 -79 Irrelevant - no brain tissue Smith, 1961 (via Fahy, 1980)
1961 Mammals (Mammalia) epididymis <0,1 -79 Irrelevant - no brain tissue Smith, 1961 (via Fahy, 1980)
1961 Mammals (Mammalia) fallopian tube <0,1 -79 Irrelevant - no brain tissue Smith, 1961 (via Fahy, 1980)
1961 Mammals (Mammalia) hypophysis <0,1 -79 Irrelevant - no brain tissue Smith, 1961 (via Fahy, 1980)
1961 Mammals (Mammalia) parathyroid glands <0,1 -79 Irrelevant - no brain tissue Russell et al, 1961 (via Fahy, 1980)
1961 Mammals (Mammalia) prostate gland (ps.) <0,1 -79 Irrelevant - no brain tissue Smith, 1961 (via Fahy, 1980)
1961 Mammals (Mammalia) seminal vesicles <0,1 -79 Irrelevant - no brain tissue Smith, 1961 (via Fahy, 1980)
1961 Mammals (Mammalia) testicular tissue <0,1 -79 Irrelevant - no brain tissue Smith, 1961 (via Fahy, 1980)
1961 Golden hamster (M. auratus) heart 0.001 -20 Irrelevant - no brain tissue Smith, 1961
1961 European rabbit (O. cuniculus) heart 0.04 -21 Irrelevant - no brain tissue Connaughton, Lewis, 1961
1961 Guinea pig (C. porcellus) uteri 0.002 -79 Irrelevant - no brain tissue Smith, 1961
1963 Domestic dog (C. lupus f.) ureters <0,1 -79 Irrelevant - no brain tissue Barner et al, 1963
1964 House mouse (M. musculus) thymus glands 0.00005 -79 Irrelevant - no brain tissue Playfair et al, 1964
1966 Cat (Felis catus) brain (in vitro) 0.03 -20 EEG similar to the control I. Suda et al, 1966
1967 Domestic dog (C. lupus f.) small intestine <0,1 -79 Irrelevant - no brain tissue Hailmton, Lehr, 1967
1972 Mammals (Mammalia) heart (fetal) <0,1 -79 Irrelevant - no brain tissue David, 1972 (via Fahy, 1980)
1973 Domestic dog (C. lupus f.) kidney 0.02 -22 Irrelevant - no brain tissue Dietzman et al, 1973
1974 Mammals (Mammalia) bone marrow <0,1 -79 Irrelevant - no brain tissue Karow et al, 1974 (via Fahy, 1980)
1974 Cat (Felis catus) brain (in vitro) 0.03 -20 activity, but some EEG abnormalities I. Suda et al, 1974
1974 Mammals (Mammalia) cornea <0,1 -79 Irrelevant - no brain tissue Karow et al, 1974 (via Fahy, 1980)
1977 Mammals (Mammalia) embryos 0.0000000005 -79 Unknown Elliot, Whelan, 1977 (via Fahy, 1980)
1977 Brown rat (R. norvegicus) pancreases (fetal) <0,1 -79 Irrelevant - no brain tissue Kemp et al, 1977 (via Fahy, 1980)
1980 Brown rat (R. norvegicus) fetal brain tissue <0,1 -90 Successful transplantation into a rat brain Houle, Das, 1980
1983 Human: unnamed donors brain tissue <0,1 -70 Metabolically, functionally active synapses Hardy et al, 1983
1984 Salamander S. keyserlingii whole 0.01 -32 Unknown Berman et al, 1984
1984 Human: unnamed donors astrocytes (culture) <0,1 -70 Astrocytes were growing in culture Kim et al, 1984
1986 Brown rat (R. norvegicus) fetal brain cells <0,1 -90 cultures indistinguishable from controls Kawamoto, Barrett, 1986
1986 Human: unnamed donors oocytes 0.0000000005 -196 Irrelevant - no brain tissue Chen, 1986
1986 Human: a 9-14 week abortus fetal brain tissue <0,1 -80 Brain cells were growing in culture Groscurth et al., 1986
1986 House mouse (M. musculus) brain cells (culture) <0,1 -15 Normal electrical activity, regeneration Scott, Lew, 1986
1986 Human: unnamed whole (embryo) 0.0000000005 -196 Likely yes (a standard praxis in 2018) Graham, 2005
1986 Human: Michelle Funk whole 10 19 Yes (no abnormalities observed) Clawson, 2013
1989 Squirrel S. parryii whole 0.9 -3 Unknown Barnes, 1989
1989 Brown rat (R. norvegicus) Pancreas (islets) 0.00000003 -196 Irrelevant - no brain tissue Warnock, Rajotte, 1989
1994 Domestic dog (C. lupus f.) whole 10 7 Yes (no abnormalities observed) Taylor et al, 1994
1999 Human: Anna Bågenholm whole 70 14 Yes (no abnormalities observed) Gilbert et al, 2000
2000 European rabbit (O. cuniculus) kidney 0.000008 -3 Irrelevant - no brain tissue Kheirabadi, Fahy, 2000
2001 Human: Erika Nordby whole 9 16 Yes (no abnormalities observed) Greaves et al, 2002
2002 Brown rat (R. norvegicus) ovaries 0.00001 -79 Irrelevant - no brain tissue Wang et al, 2002
2003 Domestic dog (C. lupus f.) whole 20 10 Yes (no abnormalities observed) Behringer et al, 2003
2003 Domestic sheep (Ovis aries) ovaries 0.0001 -140 Irrelevant - no brain tissue Bedaiwy et al, 2003
2004 European rabbit (O. cuniculus) kidney 0.000008 -45 Irrelevant - no brain tissue Fahy, 2004
2006 Domestic pig (S. domesticus) whole 50 10 Yes (no abnormalities observed) Alam et al, 2006, 2008
2007 Human: aortic surgery patients whole 70 17 Yes (no abnormalities observed) Hayashida et al, 2007
2008 Domestic pig (S. domesticus) liver 2 -40 Irrelevant - no brain tissue Gavish, 2008
2009 Beetle Upis ceramboides whole 0.0002 -60 Unknown Walters, 2009
2012 Nematodes frozen for 26 years whole 0.0000003 -20 Unknown Kagoshima et al, 2012
2015 Nematode C. elegans whole 0.0000003 -79 Yes (long-term memory preserved) Vita-More, Barranco, 2015
2016 Human: trauma patients whole 80 10 Likely yes (ongoing clinical trial) Kutcher et al, 2016
2017 Human: Tayyab Jafar whole 80 21 Yes (no abnormalities observed) Ormsby, 2017
2018 Nematodes frozen for 30+ tsd yrs whole 0.0000003 -10 Unknown Shatilovich et al, 2018
2018 Human: unnamed donors liver 2 5 Irrelevant - no brain tissue Buchholz et al, 2018