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| 2005 || April 25 || ||The Global Fund approves 33 grants to enter phase 2.<ref name="Global health the Global Fund to fight AIDS, TB and malaria is responding to challenges but needs better information and documentation for performancebased funding : report to congressional committees."/> ||
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| 2005 || August || Withdraw || The Global Fund withdraws from Burma due to new local government restrictions to project sites and more complicated regulations regarding the procurement of medical supplies.<ref>{{cite book|last1=Dittmer|first1=Lowell|title=Burma Or Myanmar?: The Struggle for National Identity|url=https://books.google.com.ar/books?id=aoHP2Q2I1p4C&pg=PA97&lpg=PA97&dq=The+Global+Fund+to+Fight+AIDS,+Tuberculosis+and+Malaria+%22in+august%22&source=bl&ots=CaIaQSNN-U&sig=9jK-a75tUn-lxBJ8IaAFOZPcmLc&hl=en&sa=X&ved=0ahUKEwizq5iG7dzTAhUFgJAKHZy_BSk4ChDoAQggMAA#v=onepage&q=The%20Global%20Fund%20to%20Fight%20AIDS%2C%20Tuberculosis%20and%20Malaria%20%22in%20august%22&f=false|accessdate=7 May 2017}}</ref> || [[wikipedia:Burma|Burma]]
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| 2005 || September || || The Global Fund holds its Eleventh Board Meeting. The Round 5 proposals are approved for US$382 million for 26 grants in 20 countries.<ref name="Global Fund Overview"/> || [[wikipedia:Switzerland|Switzerland]] ([[wikipedia:Geneva|Geneva]])
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| 2005 || December || || The Global Fund holds its Twelfth Board Meeting. The Board votes to fully fund Round 5, allocating new grants for US$719 million.<ref name="Global Fund Overview"/> || [[wikipedia:Morocco|Morocco]] ([[wikipedia:Marrakesh|Marrakesh]])
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| 2007 || March || || Following a competitive selection process, French physician [[wikipedia:Michel Kazatchkine|Michel Kazatchkine]] is selected as the Fund’s new executive director.<ref name="Working Group on Value for Money"/> ||
| 2007 || September || || The Global Fund concludes its Second Replenishment with a total amount of US$9.7 billion pledged for the period 2008-2010.<ref name="Global Fund Overview"/> ||
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| 2007 || November || || The Global Fund holds its Sixteenth Board Meeting. The Board approves 73 grants in Round 7 of funding for a total of US$1.1 billion, for 136 countries.<ref name="Global Fund Overview"/> || China Kunming
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| 2008 || November || || The Global Fund holds its Eighteenth Board Meeting. The Board approves 94 Round 8 grants for a total value of US$2.75 billion (the highest amount ever approved). The Round 9 Call for Proposals is launched.<ref name="Global Fund Overview"/> || [[wikipedia:India|India]] ([[wikipedia:New Delhi|New Delhi]])
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| 2009 || November || || The Global Fund holds its Twentieth Board Meeting. The Board approves Round 9 grants for a total value of US$2.4 billion.<ref name="Global Fund Overview"/> || [[wikipedia:Ethiopia|Ethiopia]] ([[wikipedia:Addis Abeba|Addis Abeba]])
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| 2010 || || Policy || Round 10 releases a series of information notes on harm reduction, making clear that the Global Fund “supports evidence-based interventions aimed at ensuring that key populations have access to HIV prevention, treatment, care and support … [including] the comprehensive package for the prevention, treatment and care of HIV among people who inject drugs”.<ref name="The Global Fund to Fight AIDS, Tuberculosis and Malaria's investments in harm reduction through the rounds-based funding model (2002–2014)"/> ||
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| 2010 || March || || The preparatory meeting for the Third Replenishment is held. Global Fund launches its Born HIV Free campaign, with aims at contributing to the effort for preventing children to be born with HIV.<ref name="">{{cite web|title=‘BORN HIV FREE’ campaign launched by The Global Fund|url=http://www.unaids.org/en/resources/presscentre/featurestories/2010/may/20100519gflaunches|website=unaids.org|accessdate=6 May 2017}}</ref><ref name="Global Fund Overview"/> || [[wikipedia:Netherlands|Netherlands]] ([[wikipedia:The Hague|The Hague]])
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| 2010 || October || || The United States president [[wikipedia:Barack Obama|Barack Obama]] administration announces a three-year (FY11-FY13), $4 billion pledge to the Global Fund. It would be the first time the United States make a multi-year pledge to the Global Fund.<ref name="The U.S. & The Global Fund to Fight AIDS, Tuberculosis and Malaria">{{cite web|title=The U.S. & The Global Fund to Fight AIDS, Tuberculosis and Malaria|url=http://kff.org/global-health-policy/fact-sheet/the-u-s-the-global-fund-to-fight-aids-tuberculosis-and-malaria/|website=kff.org|accessdate=29 April 2017}}</ref> ||
| 2011 || May || Policy || The Board approves the new Eligibility Counterpart Financing and Prioritization Policy, which affects the way Global Fund resources are provided. Fund resources are divided into two accounts: the General Funding Pool (intended for countries with large disease burdens and limited domestic resources) and the Targeted Funding Pool.<ref name="CRS Report for Congress Prepared for Members and Committees of Congress The Global Fund to Fight AIDS, Tuberculosis, and Malaria: Issues for Congress and U.S. Contributions from FY2001 to FY2013"/> ||
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| 2011 || June 23 || Collaboration || The Global Fund announces having signed an agreement with the [[wikipedia:International Aid Transparency Initiative|International Aid Transparency Initiative]], a multilateral effort (including donors, countries, and civil society organizations) to publicly disclose aid data in a standardized, timely approach.<ref name="CRS Report for Congress Prepared for Members and Committees of Congress The Global Fund to Fight AIDS, Tuberculosis, and Malaria: Issues for Congress and U.S. Contributions from FY2001 to FY2013">{{cite web|title=CRS Report for Congress Prepared for Members and Committees of Congress The Global Fund to Fight AIDS, Tuberculosis, and Malaria: Issues for Congress and U.S. Contributions from FY2001 to FY2013|url=https://fas.org/sgp/crs/misc/R41363.pdf|website=fas.org|accessdate=6 May 2017}}</ref> ||
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| 2012 || || Report || Data released from analysis from Round 1 (2002) to Round 9 (2009) shows that the Global Fund has invested or approved US$ 430 million for activities that specifically targets people who inject drugs.<ref name="The Global Fund to Fight AIDS, Tuberculosis and Malaria's investments in harm reduction through the rounds-based funding model (2002–2014)"/> ||
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| 2013 || February || Policy || The Global Fund announces a new funding model, under which funding allocations would be determined for each eligible country based on calculations of country income and national disease burden.<ref name="The Global Fund to Fight AIDS, Tuberculosis and Malaria's investments in harm reduction through the rounds-based funding model (2002–2014)">{{cite journal|title=The Global Fund to Fight AIDS, Tuberculosis and Malaria's investments in harm reduction through the rounds-based funding model (2002–2014)|doi=10.1016/j.drugpo.2015.08.001|url=http://www.sciencedirect.com/science/article/pii/S0955395915002364|accessdate=5 May 2017}}</ref> ||
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| 2013 || March || Policy || The Global Fund starts transitioning into its new funding model by inviting select early applicants and interim applicants to submit concept notes for funding.<ref name="Global Fund Overview"/> ||
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| 2013 || June || || The Global Fund's Twenty-ninth Board Meeting is held. Among other decisions, a new Inspector General is appointed. Also, the Board awards grants to the first three countries to receive funding under the new funding model.<ref name="Global Fund Overview"/> || [[Wikipedia:Sri Lanka|Sri Lanka]] ([[wikipedia:Colombo|Colombo]])
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| 2013 || December || || The United States president [[wikipedia:Barack Obama|Barack Obama]] administration at the White House hosts the Global Fund’s Fourth Replenishment, and launches the 2014-2016 replenishment cycle with a total amount of US$12 billion pledged.<ref name="Global Fund Overview"/> || [[wikipedia:United States|United States]] ([[wikipedia:Washington, D.C.|Washington D.C.]])
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