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| 2003 || || Administration || The Global Fund adopts a three-year replenishment model to guarantee countries of sustained and predictable financial support for their programs.<ref>{{cite web|title=The Global Fund to Fight AIDS, Tuberculosis and Malaria|url=http://www.gbchealth.org/newsletters/insights-the-global-fund-to-fight-aids-tuberculosis-and-malaria/|website=gbchealth.org|accessdate=7 May 2017}}</ref> ||
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| 2003 || January || Administration || The Global Fund Fourth Board Meeting approves the second round of grant proposals (US$900 million in grants to 72 countries).<ref name="Global health the Global Fund to fight AIDS, TB and malaria is responding to challenges but needs better information and documentation for performancebased funding : report to congressional committees."/><ref name="Global Fund Overview"/> ||
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| 2003 || August || Report || The total disbursements by the Global Fund to countries surpass US$100 million.<ref name="Global Fund Overview"/> ||

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