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| 1898 || Field development || German surgeon {{w|August Bier}} performs the first operation under {{w|spinal anaesthesia}}.<ref name="History of Anesthesia"/> ||
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| 1901 || Field development || "Caudal epidural analgesia is described independently by France's Drs. Jean-Anthanase Sicard and Fernand Cathelin. Their innovation comes after an inadvertent from {{w|France}} describe independently caudal epidural injection by Dr. J. Leonard Corning (1855-1923)analgesia.<ref name="History of Anesthesia"/> ||{{w|France}}
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| 1902 || Field development || "Dr. Mathias J. Seifert of in {{w|Chicago }} coins the words "anesthesiology" and "anesthesiologist." He asserted Seifert asserts that an "ANESTHETISTanesthetist" is a technician and an "ANESTHESIOLOGISTanesthesiologist" is the scientific authority on anesthesia and anesthetics."<ref name="History of Anesthesia"/> ||{{w|United States}}
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| 1905 || Organization || The Long Island Society of Anesthetists (LISA) is founded as the first professional anesthesia society in the United States.<ref name="History of Anesthesia"/> || {{w|United States}}
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| 1905 || Drug || German chemist {{w|Alfred Einhorn}} first synthesizes {{w|procaine}} and names the substance "novocain".<ref name="History of Anesthesia"/> || {{w|Germany}}
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| 1909 || Field development || Endotracheal anesthesia is introduced by Samuel James Meltzer and John Auer.<ref name="A Dictionary of the History of Medicine"/> ||
