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| 1999 || || USAID begins disbursing multimillion dollar grants for anti-trafficking projects in Russia and Ukraine.<ref>{{cite book |title=Gender, Politics, and Society in Ukraine |edition=Olena Hankivsky, Anastasiya Salnykova |url=https://books.google.com.ar/books?id=n9MOMCO5SJ8C&pg=PA107&lpg=PA107&dq=%22in+1999+usaid%22&source=bl&ots=fsDpSngSXL&sig=ACfU3U17cZ_BvzWkuNSPCED0fpseG_ymTw&hl=en&sa=X&ved=2ahUKEwi7g9jY6LfhAhXeF7kGHcvAAVgQ6AEwBXoECAgQAQ#v=onepage&q=%22in%201999%20usaid%22&f=false}}</ref> || {{w|Russia}}, {{w|Ukraine}}
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| 2000 || || USAID funds a large regional anti-trafficking effort for South Asia, managed by the {{w|United Nations Development Fund for Women}} (UNIFEM), focused on prevention and education in {{w|Bangladesh}}, {{w|India}}, {{w|Nepal}}, {{w|Pakistan}} and {{w|Sri Lanka}}.<ref>{{cite web |title=Trafficking in Persons: USAID’s Response |url=http://www.childtrafficking.org/pdf/user/trafficking%20_in_persons_usaids_response.pdf |website=childtrafficking.org |accessdate=17 April 2019}}</ref> || {{w|South Asia}}
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| 2003 || || {{w|United States President}} {{w|George W. Bush}} establishes PEPFAR, the {{w|President's Emergency Plan for AIDS Relief}}, putting USAID's HIV/AIDS programs under the direction of the State Department's new Office of the {{w|Global AIDS Coordinator}}.<ref>{{cite web |url=http://www.pepfar.gov/agencies/c19390.htm |title=Department of State (DoS) |publisher=Pepfar.gov |date=2006-11-15 |accessdate=2011-03-12 |archive-url=https://web.archive.org/web/20110728032409/http://www.pepfar.gov/agencies/c19390.htm |archive-date=2011-07-28 |dead-url=yes }} For the nature of the emergency and the U.S. Government response, see {{cite web |last1=U.S. Government Accountability Office |title=Intellectual Property: U.S. Trade Policy Guidance on WTO Declaration on Access to Medicines May Need Clarification (GAO-07-1198) |url=https://www.gao.gov/assets/270/267756.pdf |accessdate=30 March 2019 |date=September 2007}}</ref> ||