Timeline of borderline personality disorder
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Big picture
| Time period | Development summary | More details |
|---|
Full timeline
| Year | Month and date | Event type | Details |
|---|---|---|---|
| 1998 | Zanarini et al. publish a study aimeing to identify dysphoric states specific to BPD compared to other personality disorders. They administer the Dysphoric Affect Scale to 146 BPD patients and 34 Axis II controls. Results show 25 dysphoric states more common in BPD patients, with 25 being highly specific to BPD. These states cluster into extreme feelings, destructiveness, fragmentation, and victimization. Some specific states like feeling betrayed and out of control strongly associate with BPD. Overall, Dysphoric Affect Scale scores accurately distinguishes BPD from other personality disorders in 84% of cases, suggesting the pervasive and multifaceted nature of subjective pain in BPD.[1] | ||
| 2014 | May | A study investigates the phenomenon of self-injurious behaviors (SIB) and the intriguing lack of pain perception in many BPD patients during SIB. The study explores the relationship between affective dysregulation and physical pain, highlighting the inadequacy of SIB as a coping mechanism for emotional distress. Neuroimaging data suggest abnormalities in brain activation patterns, particularly in the dorsolateral prefrontal cortex and insula, which may contribute to altered pain sensitivity in BPD. Therapeutic interventions targeting these neurobiological dysfunctions show promise for improving pain perception and management in BPD patients.[2] | |
| 2015 | December 22 | Research | A study investigates the impact of BPD on obstetrical and neonatal outcomes. Conducted from 2003 to 2012, it analyzes 989 births to women with BPD. Findings reveal that women with BPD, often younger and of lower socioeconomic status, faced increased risks during pregnancy, including gestational diabetes, premature rupture of membranes, chorioamnionitis, venous thromboembolism, caesarian delivery, and preterm birth. Notably, BPD is not linked with postpartum hemorrhage or instrumental delivery and is negatively associated with induction of labor. The study emphasizes the importance of closely monitoring pregnant women with BPD to mitigate adverse outcomes through multidisciplinary care.[3] |
| 2022 | February 26 | Research | A systematic review and meta-analysis investigates the prevalence of BPD and borderline personality features (BPF) during the perinatal period. Conducted by Divya Prasad and colleagues, the study examines 16 publications, including 14 research articles and 2 conference abstracts, gathered from PubMed, PsycINFO, and Embase. Among non-clinical samples, BPF prevalence during pregnancy ranges from 6.9% to 26.7%, while BPD rates across the perinatal period ranges from 0.7% to 1.7%. Clinical samples exhibit higher rates, with BPF and BPD ranging from 9.7% to 34% and 2.0% to 35.2%, respectively. The meta-analysis reveal a pooled BPD prevalence of 14.0% (95% CI [7.0, 22.0]) among clinical perinatal samples, indicating a significant prevalence of borderline personality pathology. The review underscores the importance of validated screening methods for identifying and treating BPD in the perinatal population.[4] |
| 2022 | September | Fitzpatrick et al. conduct a study aiming to determine if BPD is truly an emotion dysregulation disorder and, if so, in what ways. Their unified paradigm assesses five main components of emotion dysregulation in individuals with BPD compared to those with generalized anxiety disorder (GAD) and healthy controls (HCs). Results show higher self-reported and sympathetic baseline emotion in BPD and GAD groups compared to HCs. Additionally, individuals with BPD exhibit emotion regulation deficits specifically in distraction compared to the GAD group. The findings suggest that while some aspects of emotion dysregulation are present in BPD, others may be common across high emotion dysregulation groups.[5] |
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References
- ↑ Fitzpatrick, Skye; Varma, Sonya; Kuo, Janice R. (September 2022). "Is borderline personality disorder really an emotion dysregulation disorder and, if so, how? A comprehensive experimental paradigm". Psychological Medicine. 52 (12): 2319–2331. ISSN 1469-8978. doi:10.1017/S0033291720004225.
- ↑ Ducasse, Déborah; Courtet, Philippe; Olié, Emilie (May 2014). "Physical and social pains in borderline disorder and neuroanatomical correlates: a systematic review". Current Psychiatry Reports. 16 (5): 443. ISSN 1535-1645. doi:10.1007/s11920-014-0443-2.
- ↑ Pare-Miron, Valerie; Czuzoj-Shulman, Nicholas; Oddy, Lisa; Spence, Andrea R.; Abenhaim, Haim Arie (2016). "Effect of Borderline Personality Disorder on Obstetrical and Neonatal Outcomes". Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health. 26 (2): 190–195. ISSN 1878-4321. doi:10.1016/j.whi.2015.11.001.
- ↑ Prasad, Divya; Kuhathasan, Nirushi; de Azevedo Cardoso, Taiane; Suh, Jee Su; Frey, Benicio N. (April 2022). "The prevalence of borderline personality features and borderline personality disorder during the perinatal period: a systematic review and meta-analysis". Archives of Women's Mental Health. 25 (2): 277–289. ISSN 1435-1102. doi:10.1007/s00737-022-01218-8.
- ↑ Fitzpatrick, Skye; Varma, Sonya; Kuo, Janice R. (September 2022). "Is borderline personality disorder really an emotion dysregulation disorder and, if so, how? A comprehensive experimental paradigm". Psychological Medicine. 52 (12): 2319–2331. ISSN 1469-8978. doi:10.1017/S0033291720004225.
