Difference between revisions of "Timeline of immunology"
From Timelines
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| 1949 || || " Macfarlane Burnet & Frank Fenner formulate immunological tolerance hypothesis."<ref name="History of immunology"/> || | | 1949 || || " Macfarlane Burnet & Frank Fenner formulate immunological tolerance hypothesis."<ref name="History of immunology"/> || | ||
|- | |- | ||
| − | | 1950 || || Howard Gershon and Koichi S. Kondo discover suppressor T cells. || | + | | 1950 || || Howard Gershon and Koichi S. Kondo discover suppressor T cells.<ref name="A Text Book of Immunology"/> || |
|- | |- | ||
| 1953 || || J.F. Riley and G.B. West discover histamine in mast cells. || | | 1953 || || J.F. Riley and G.B. West discover histamine in mast cells. || | ||
Revision as of 15:40, 3 August 2018
This is a timeline of immunology.
Contents
Big picture
| Time period | Development summary |
|---|
Full timeline
| Year | Event type | Details | Country/region |
|---|---|---|---|
| 430 BC | "Nevertheless, there were intimations as early as 430 B.C. that if one survived a disease, the person thereafter became "immune" to any subsequent exposures."[1] | ||
| 1700 | "Although most historical accounts credit Edward Jenner for the development of the first immunization process, a previous similar procedure had become established in China by 1700. The technique was called variolation. This was derived from the name of the infective agent—the variola virus."[1] | China | |
| 1798 | " Edward Jenner initiates smallpox vaccination."[1][2][3] | ||
| 1840 | German physician Friedrich Gustav Jakob Henle proposes a germ theory of disease. | ||
| 1862 | German biologist Ernst Haeckel recognizes phagocytosis.[3] | Germany | |
| 1874 | Moritz Traube and Richard Gscheidlen inject micro-organisms into the blood and find that micro-organisms are rapidly destroyed and bloodstream maintain its sterility.[3] | ||
| 1877 | German Jewish physician Paul Ehrlich first describes mast cells.[4][1][3] | ||
| 1878 | Louis Pasteur confirms and popularizes the germ theory of disease. | ||
| 1883 | Russian zoologist Ilya Ilyich Mechnikov theorizes that cells are involved in the defense of the body.[1][2] | ||
| 1884 | W. Grohmann notes that cell-free serum is capable of killing microorganism in vitro.[3] | ||
| 1888 | French bacteriologists Pierre Paul Émile Roux and Alexandre Yersin discover bacterial toxin, by isolating a toxin secreted by corynebacterium diphtheriae and showing that the toxin—and not the microorganism—gives rise to the symptoms of diphteria.[5][3] | France | |
| 1888 | American-British bacteriologist George Nuttall inoculates defibrinated blood with bacteria and shows that outside the body, serum retains its bactericidal activity.[3] | ||
| 1889 | Hans Buchner first identifies a principle in fresh blood that he terms as "alexin" and is capable of killing bacteria.[3] | ||
| 1889 | German bacteriologist Richard Friedrich Johannes Pfeiffer conducts a series of experiments that allow the understanding of bactericidal action of serum.[3] | Germany | |
| 1891 | Robert Koch discovers delayed type hypersensitivity.[1][2] | ||
| 1900 | Paul Ehrlich theorizes about some of the events taking place in immune cells, postulating that cells interact with toxins via "side chains" that stem from protoplasm.[3] | ||
| 1900 | Austrian biologist Karl Landsteiner discovers ABO blood group system.[3] | ||
| 1902 | Charles Richet coins the term anaphylaxis to describe the most dangerous allergic reaction.[2][3] | ||
| 1903 | ""Almoth Wright and Stewart Douglas, opsonization reactions"" | ||
| 1906 | Clemens von Pirquet coins the term allergy.[1][2][3] | ||
| 1907 | Svante Arrhenius coins the term immunochemistry.[2][3] | ||
| 1910 | Henry Dale identifies histamine, a body chemical responsible for many allergic reactions. | ||
| 1910 | "Peyton Rous, viral immunology theory" | ||
| 1916 | Robert Cook and Albert Vander Veer demonstrate the role of heredity in allergy sufferers. | ||
| 1917 | "Karl Landsteiner, haptens" [3] | ||
| 1921 | Carl Prausnitz and Heinz Küstner discover that components in the blood can reproduce food allergy reactions.[2][3] | ||
| 1924 | Ludwig Aschoff adopts the term reticuloendothelial system (RES).[3][6][7] | ||
| 1926 | Lloyd D. Felton isolates pure antibody preparation.[3] | ||
| 1930 | "Elvin Kabat, discovery of role of gamma-globulin"[3] | ||
| 1934 | John Marrack advances the antigen-antibody binding hypothesis.[3] | ||
| 1936 | Peter Gorer identifies the H-2 antigen in mice.[3] | ||
| 1937 | David Bovet synthesizes the first antihistamine. | ||
| 1938 | "John Marrack formulates antigen-antibody binding hypothesis."[1] | ||
| 1940 | Karl Landsteiner and Alexander S. Weiner identify Rh antigens.[3] | ||
| 1941 | Albert Coons develops immunofluorescence technique. | ||
| 1942 | "Jules Freund and Katherine McDermott research adjuvants."[1] | ||
| 1944 | Peter Medawar develops the immunological hypothesis of allograft rejection.[1] | ||
| 1948 | Astrid Fagraeus demonstrates the production of antibodies in plasma B cells.[1] | ||
| 1948 | "George Snell, congenic mouse lines".[1] | ||
| 1949 | " Macfarlane Burnet & Frank Fenner formulate immunological tolerance hypothesis."[1] | ||
| 1950 | Howard Gershon and Koichi S. Kondo discover suppressor T cells.[3] | ||
| 1953 | J.F. Riley and G.B. West discover histamine in mast cells. | ||
| 1957 | British virologist Alick Isaacs and Suiss colleague Jean Lindemann discover interferon.[8][1][9] | ||
| 1958 | Jean Dausset discovers human leukocyte antigens. | ||
| 1959 | Rodney Porter discovers antybody structure. | ||
| 1959 | "Niels Jerne, David Talmage, Macfarlane Burnet develop clonal selection theory."[1] | ||
| 1962 | "Rodney Porter and team discovery the structure of antibodies."[1] | ||
| 1962 | "Jaques Miller and team discover thymus involvement in cellular immunity."[1] | ||
| 1962 | "Noel Warner and team distinguish between cellular and humoral immune responses."[1] | ||
| 1964 | Anthony Davis identifies T and B cell cooperation in immune response. | ||
| 1967 | Teruko and Kimishige Ishizaka identify IgE, the allergy antibody. | ||
| 1968 | " Anthony Davis and team discover T cell and B cell cooperation in immune response."[1] | ||
| 1974 | "Rolf Zinkernagel and Peter Doherty explore major histocompatibility complex restriction."[1] | ||
| 1985 | Susumu Tonegawa and Leroy Hood identify immunoglobulin genes."[1] | ||
| 1985 | Leroy Hood identifies genes for the T. cell receptor. | ||
| 1985 | "Scientists begin the rapid identification of genes for immune cells that continues to the present."[1] | ||
| 1987 | " Leroy Hood and team identify genes for the T cell receptor."[1] | ||
| 1990 | Leroy Hood identifies genes for the T. cell receptor. | ||
| 2000 | FDA approves the first anti-IgE drug, rhu-MAb-E25. |
Meta information on the timeline
How the timeline was built
The initial version of the timeline was written by FIXME.
Funding information for this timeline is available.
Feedback and comments
Feedback for the timeline can be provided at the following places:
- FIXME
What the timeline is still missing
Timeline update strategy
See also
External links
References
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 "History of immunology". encyclopedia.com. Retrieved 1 August 2018.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Rejaunier, Jeanne; Freund, Lee. The Complete Idiot's Guide to Food Allergies.
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 3.15 3.16 3.17 3.18 3.19 3.20 3.21 3.22 Sinha, J.K.; Bhattacharya, S. A Text Book of Immunology.
- ↑ McCance,, Kathryn L.; Huether, Sue E. Pathophysiology E-Book: The Biologic Basis for Disease in Adults and Children.
- ↑ "Alexandre Yersin". britannica.com. Retrieved 3 August 2018.
- ↑ Martinez, A. Julio. "The Role of the Reticuloendothelial System in Infections of the Central Nervous System". link.springer.com. Retrieved 3 August 2018.
- ↑ Friedman, Herman. The Reticuloendothelial System: A Comprehensive Treatise Volume 5 Cancer.
- ↑ Erling, Norrby. Nobel Prizes And Nature's Surprises.
- ↑ "Interferon Discoverer Dies". the-scientist.com. Retrieved 3 August 2018.
