Difference between revisions of "Timeline of malaria in 2015"

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| July 8 || || {{w|Sanofi}} teams with its partners at {{w|Medicines for Malaria Venture}} (MMV) with the purpose of developing a single-dose treatment for malaria, advancing a pair of candidates through mid-stage development.<ref>{{cite web|title=Sanofi advances a one-shot malaria program as drug resistance spreads|url=http://www.fiercebiotech.com/partnering/sanofi-advances-a-one-shot-malaria-program-as-drug-resistance-spreads|website=fiercebiotech.com|accessdate=15 July 2017}}</ref> ||
 
| July 8 || || {{w|Sanofi}} teams with its partners at {{w|Medicines for Malaria Venture}} (MMV) with the purpose of developing a single-dose treatment for malaria, advancing a pair of candidates through mid-stage development.<ref>{{cite web|title=Sanofi advances a one-shot malaria program as drug resistance spreads|url=http://www.fiercebiotech.com/partnering/sanofi-advances-a-one-shot-malaria-program-as-drug-resistance-spreads|website=fiercebiotech.com|accessdate=15 July 2017}}</ref> ||
 
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|-
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| July 14 || || "goal set – to bring malaria deaths to near zero in the next 15 years"<ref>{{cite web|title=Here's how to wipe malaria off the map|url=https://www.theguardian.com/global-development/2015/jul/14/wipe-malaria-off-map-global-commitment-reduce-disease|website=theguardian.com|accessdate=14 July 2017}}</ref> ||
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| July 14 || || The global community agrees to reduce deaths by 90%, and eliminate malaria in at least 35 countries by 2030, amid the negotiations taking place at the third international financing for development conference in {{w|Addis Ababa}}. Experts estimate that the cost of achieving such goals would be US$ 100bn, which requires to raise $6.5bn per year by 2020. <ref>{{cite web|title=Here's how to wipe malaria off the map|url=https://www.theguardian.com/global-development/2015/jul/14/wipe-malaria-off-map-global-commitment-reduce-disease|website=theguardian.com|accessdate=14 July 2017}}</ref> || {{w|Ethiopia}}
 
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| July 16 || || "Mosquitoes Can Carry, and Deliver, a Double Dose of Malaria"<ref>{{cite web|title=Mosquitoes Can Carry, and Deliver, a Double Dose of Malaria|url=http://www.smithsonianmag.com/science/mosquitoes-can-carry-deliver-double-dose-malaria-180955935/|website=smithsonianmag.com|accessdate=14 July 2017}}</ref> ||
 
| July 16 || || "Mosquitoes Can Carry, and Deliver, a Double Dose of Malaria"<ref>{{cite web|title=Mosquitoes Can Carry, and Deliver, a Double Dose of Malaria|url=http://www.smithsonianmag.com/science/mosquitoes-can-carry-deliver-double-dose-malaria-180955935/|website=smithsonianmag.com|accessdate=14 July 2017}}</ref> ||

Revision as of 13:31, 26 September 2017

This is a timeline of malaria in 2015.

Development summary

  • Parasites:
  • Vectors:
  • Drugs, vaccines, treatment, and control methods:
  • Eradication and control progress:
  • Vector control: The population at risk in Sub-Saharan Africa sleeping under an insecticide-treated mosquito net (ITN) or protected by indoor residual spraying (IRS) 57% (up from 37% in 2010).[1]

Key figures

Global cases 214 million (range 149–303 million)[2]
Global deaths 438,000 (range 236,000–635,000)[2]
Deaths among children 306,000 (range 219,000–421,000)[2]
Distribution 88% of cases and 90% of deaths occurred in the WHO African Region. 10% of cases and 7% of deaths occurred in the WHO South-East Asia Region. Nigeria and Democratic Republic of Congo, accounted for more than 35% of global malaria deaths.[2]
Malaria financing US$ 2.9 billion[1]

Full timeline

Month/date Event type Details Country
January 17 Scientists identify mutations in the parasite genome that are linked to resistance, a growing problem in South East Asia.[3]
February 5 Artificial intelligence named Eve, created specifically to automate the early stages of drug design, finds compounds with the potencial of combating drug-resistant malaria.[4][5][6]
February 15 Scientists report that drug-resistant malaria is on the cusp of re-emerging in India, after the strain is detected near the country’s border in Myanmar.[7] India
March 18 Scientist in Michigan publishes research indicating devastating effects of malaria in the brain.[8] United States
March 19 Researchers describe definitively that in children infected with malaria, brain swelling crushes the brainstem, which is where the neural stimulus for breathing originates, causing some children to die from cerebral malaria.[9]
March 25 Research team at Washington University School of Medicine in Saint Louis, Missouri finds that the parasite that causes malaria produces an odor which attracts mosquitoes, inviting more bites and infections.[10] United States
April 24 Clinical trial results of malaria vaccine candidate RTS,S shows partial protection for up to four years. [11][12]
April 24 Statistics In Africa, where 80 percent of malaria cases occur, malaria costs an estimated minimum of US$ $12 billion in lost productivity each year. In some high-burden countries the disease is estimated to account for as much as 40% of public health expenditure.[13]
May 8 Malaria vaccine candidate developed at Oxford University is found to be 67% effective in a study of 121 men in Kenya.[14]
May 21 Medical researchers at University of Oxford find that malaria drug hydroxychloroquine reduces heart rate significantly. The drug was also found useful in the treatment of rheumatoid arthritis and lupus}.[15] United Kingdom
June 17 Researchers at Dundee University discover a new compound which could treat malaria while protecting people from the disease and preventing its spread, all in a single dose.[16][17][18] United Kingdom
June 24 Study suggests that malaria likely killed many more people than usual in the west African nation of Guinea during the West African Ebola virus epidemic, as tens of thousands with potential signs of the mosquito-spread disease probably shunned health clinics.[19] Tens of thousands of malaria cases would have gone untreated in Guinea last year as people with symptoms shunned health clinics for fear of being sent into isolation at Ebola treatment centres, according to authoritative research. The study suggests that far more people will have died from malaria in 2014 than Ebola, which had killed 2,444 people by 15 June of 2015.[20]
July 8 Sanofi teams with its partners at Medicines for Malaria Venture (MMV) with the purpose of developing a single-dose treatment for malaria, advancing a pair of candidates through mid-stage development.[21]
July 14 The global community agrees to reduce deaths by 90%, and eliminate malaria in at least 35 countries by 2030, amid the negotiations taking place at the third international financing for development conference in Addis Ababa. Experts estimate that the cost of achieving such goals would be US$ 100bn, which requires to raise $6.5bn per year by 2020. [22] Ethiopia
July 16 "Mosquitoes Can Carry, and Deliver, a Double Dose of Malaria"[23]
July 16 "Researchers at UT Southwestern Medical Center and in Australia have shown that a drug currently in testing shows potential to cure malaria in a single dose and offers promise as a preventive treatment as well."[24]
July 17 "Parkinson's disease may be treatable with antimalaria drugs"[25]
July 24 Endorsement European drugs regulators recommend RTS,S (trade name Mosquirix), as safe and effective to use in babies in Africa at risk of the mosquito-borne disease.[26] "The first malaria vaccine is set to be given the green light by regulators on Friday, opening the door for the World Health Organization to recommend its use in developing countries."[27][28]
August 5 "Researchers say an African spider that preys on malaria-carrying mosquitos to get the blood they suck from humans should be used to fight the disease"[29]
October 23 "World Health Organization advisory committee endorses use of the RTS,S vaccine in small-scale demonstrations."[30]
September 11 "Can dams increase the risk of malaria?"[31][32][33]
September 17 "The report published in the journal Nature showed that overall the number of infections fell by 50% across the continent."[34]
September 20 "Drug Goes From $13.50 a Tablet to $750, Overnight"[35] United States
September 28 " A new report released by the United Nations and the Bill & Melinda Gates Foundation presents a vision to eradicate malaria by 2040 that involves new strategies, tools and financing and urges world leaders to expand their commitments to fight a disease that still kills about one child every minute."[36]
October 5 Award Chinese pharmaceutical chemist Tu Youyou is awarded the 2015 Nobel Prize in Physiology or Medicine "for her discoveries concerning a novel therapy against Malaria". Youyou discovered artemisinin (also known as qinghaosu) and dihydroartemisinin.[37][38]
October 14 "Scientists might have accidentally made a huge step forward in the search for a cure for cancer — discovering unexpectedly that a malaria protein could be an effective weapon against the disease."[39][40][41][42]
October 20 "A drug-resistant malaria parasite found in South East Asia can also infect mosquito species in Africa, a study shows."[43]
November 9 "AUSTRALIAN scientists will infect healthy people with malaria in a bold new research project boosted by $10 million in funding from Microsoft founder Bill Gates."[44]
November 10 "Army malaria drug mefloquine safety inquiry to start"[45]
November 23 Scientific development (vector) Research team from the University of California uses CRISPR-Cas9 genome-editing method to insert a package of new genes into 680 embryos of Anopheles stephensi with the purpose of altering their DNA in order to block the parasite that carries malaria, and having within a few generations virtually all the insects’ descendants the antimalaria DNA inherited. The researchers would discuss the possibility that lab-engineered insects could be released into the wild to stop malaria.[46] California
November 23 "UK sets up £1bn fund to combat malaria and other infectious diseases."[47][48]
November 23 "University of California scientists create malaria-blocking mosquitoes"[49][50]
December The World Health Organization officially certifies the Republic of Maldives as the first malaria-free country in the South-East Asia WHO Region.[51] Maldives
December 9 Report The World Malaria Report is published. A total of 438,000 deaths due to malaria are reported worldwide during the year, with most occuring in the African Region (90%), followed by the South-East Asia Region (7%) and the Eastern Mediterranean Region (2%).[52][53] "Other key findings":" In 2015, 89% of all malaria cases and 91% of deaths were in sub-Saharan Africa.""Of the 106 countries and territories with malaria transmission in 2000, 102 are projected to reverse the incidence of malaria by the end of 2015.""Between 2000 and 2015, the proportion of children under 5 sleeping under an ITN in sub-Saharan Africa increased from less than 2% to an estimated 68%.""1 in 4 children in sub-Saharan Africa still lives in a household with no ITN and no protection provided by indoor residual spraying."[54]
December 8 "On Monday, scientists from Imperial College London announced in the journal Nature Biotechnology that they had successfully genetically modified Anopheles gambiae, the mosquito that is a major malaria vector, to carry infertile traits. The modification process uses a breakthrough technology called CRISPR, a genome editing tool."[55][56]

Meta information on the timeline

How the timeline was built

The initial version of the timeline was written by User:Sebastian.

Funding information for this timeline is available.

What the timeline is still missing

Timeline update strategy

See also

External links

References

  1. ↑ 1.0 1.1 "WORLD MALARIA REPORT" (PDF). who.int. Retrieved 13 July 2017. 
  2. ↑ 2.0 2.1 2.2 2.3 "New report signals country progress in the path to malaria elimination". who.int. Retrieved 13 July 2017. 
  3. ↑ Morelle, Rebecca. "Genetics of malaria drug resistance revealed". bbc.com. Retrieved 14 July 2017. 
  4. ↑ "Robot Scientist Discovers Potential Malaria Drug". scientificamerican.com. Retrieved 13 July 2017. 
  5. ↑ "Eve the robot scientist discovers new drug candidate for malaria". engadget.com. Retrieved 13 July 2017. 
  6. ↑ "Malaria Treatment And Other Cures May Soon Be Found By Artificially Intelligent Robots". medicaldaily.com. Retrieved 13 July 2017. 
  7. ↑ "New Strain of Drug-Resistant Malaria Could Reach India". wsj.com. Retrieved 13 July 2017. 
  8. ↑ "How Malaria In The Brain Kills: Doctors Solve A Medical Mystery". npr.org. Retrieved 13 July 2017. 
  9. ↑ "Why Malaria Kills Babies, and a Path to Finding New Treatments". newsweek.com. Retrieved 13 July 2017. 
  10. ↑ Berman, Jessica. "Mosquitoes Attracted to Malaria Parasite in People". voanews.com. Retrieved 13 July 2017. 
  11. ↑ "World's First Viable MalariaVaccine Shows Success in Trials". time.com. Retrieved 13 July 2017. 
  12. ↑ "Malaria vaccine a breakthrough despite being partially effective, say scientists". theguardian.com. Retrieved 13 July 2017. 
  13. ↑ "Africa: Malaria Costs Africa U.S.$12 Billion a Year". allafrica.com. Retrieved 13 July 2017. 
  14. ↑ "Malaria 'viral' vaccine shows promising early results". bbc.com. Retrieved 14 July 2017. 
  15. ↑ Hennessy, Mark. "Malaria drug to be repurposed for the heart". irishtimes.com. Retrieved 15 July 2017. 
  16. ↑ "New anti-malaria drug developed at Dundee University". bbc.com. Retrieved 13 July 2017. 
  17. ↑ "New anti-malarial treatment provides hope in battle against drug resistance". theguardian.com. Retrieved 13 July 2017. 
  18. ↑ "Malaria drug breakthrough could lead to single dose treatment: Compound could also act as immunisation against disease". dailymail.co.uk. Retrieved 15 July 2017. 
  19. ↑ "Malaria killed more people than usual in Ebola outbreak in Guinea". telegraph.co.uk. Retrieved 13 July 2017. 
  20. ↑ "Thousands of Guinea malaria cases go untreated amid Ebola fears". theguardian.com. Retrieved 13 July 2017. 
  21. ↑ "Sanofi advances a one-shot malaria program as drug resistance spreads". fiercebiotech.com. Retrieved 15 July 2017. 
  22. ↑ "Here's how to wipe malaria off the map". theguardian.com. Retrieved 14 July 2017. 
  23. ↑ "Mosquitoes Can Carry, and Deliver, a Double Dose of Malaria". smithsonianmag.com. Retrieved 14 July 2017. 
  24. ↑ "New drug DSM265 shows potential to cure, prevent malaria". news-medical.net. Retrieved 15 July 2017. 
  25. ↑ Paddock, Catharine. "Parkinson's disease may be treatable with antimalaria drugs". medicalnewstoday.com. Retrieved 15 July 2017. 
  26. ↑ "World's first malaria vaccine gets regulatory go-ahead, faces WHO review". reuters.com. Retrieved 12 July 2017. 
  27. ↑ "Malaria vaccine: How good is good enough?". bbc.com. Retrieved 14 July 2017. 
  28. ↑ "First malaria vaccine given green light by European regulators". theguardian.com. Retrieved 14 July 2017. 
  29. ↑ "Mosquito-eating vampire spider could be recruited for war on malaria". theguardian.com. Retrieved 14 July 2017. 
  30. ↑ "Malaria vaccine cautiously recommended for use in Africa". nature.com. Retrieved 14 July 2017. 
  31. ↑ "Can dams increase the risk of malaria?". cnn.com. Retrieved 13 July 2017. 
  32. ↑ "Malaria cases in Africa are soaring. Here's the surprising reason why.". washingtonpost.com. Retrieved 13 July 2017. 
  33. ↑ "One million Africans a year catch malaria from dam mosquitoes". enca.com. Retrieved 13 July 2017. 
  34. ↑ "Malaria: '700 million cases' stopped in Africa". bbc.com. Retrieved 14 July 2017. 
  35. ↑ "Drug Goes From $13.50 a Tablet to $750, Overnight". nytimes.com. Retrieved 15 July 2017. 
  36. ↑ "Report by UN and Gates Foundation presents vision for eradicating malaria by 2040". un.org. Retrieved 13 July 2017. 
  37. ↑ "Youyou Tu - Facts". nobelprize.org. Retrieved 12 July 2017. 
  38. ↑ "A Chinese pharmacologist who discovered a treatment for malaria in an ancient Chinese remedy gets a Nobel prize". pri.org. Retrieved 12 July 2017. 
  39. ↑ "Cure for cancer might accidentally have been found, and it could be malaria". independent.co.uk. Retrieved 13 July 2017. 
  40. ↑ "Cancer breakthrough as scientists create MALARIA protein that could 'destroy nine in 10 cancers'". dailymail.co.uk. Retrieved 13 July 2017. 
  41. ↑ "Malaria protein may hold key for cancer cure, scientists say". foxnews.com. Retrieved 13 July 2017. 
  42. ↑ "Malaria vaccine provides hope for a general cure for cancer". ku.dk. Retrieved 13 July 2017. 
  43. ↑ "Drug-resistant malaria can infect African mosquitoes". bbc.com. Retrieved 15 July 2017. 
  44. ↑ "Bill Gates funds Australian malaria research". news.com.au. Retrieved 15 July 2017. 
  45. ↑ "Army malaria drug mefloquine safety inquiry to start". bbc.com. Retrieved 15 July 2017. 
  46. ↑ "Mosquito DNA altered to block malaria, not spread it". statnews.com. Retrieved 12 July 2017. 
  47. ↑ "UK sets up £1bn fund to combat malaria and other infectious diseases". theguardian.com. Retrieved 13 July 2017. 
  48. ↑ "George Osborne teams with Bill Gates in bid to eradicate malaria". independent.co.uk. Retrieved 13 July 2017. 
  49. ↑ "University of California scientists create malaria-blocking mosquitoes". uci.edu. Retrieved 14 July 2017. 
  50. ↑ Roberts, Michelle. "Mutant mosquitoes 'resist malaria'". bbc.com. Retrieved 14 July 2017. 
  51. ↑ "Malaria-free Maldives". who.int. Retrieved 11 July 2017. 
  52. ↑ "World Malaria Report 2015" (PDF). who.int. Retrieved 12 July 2017. 
  53. ↑ "Malaria deaths drop below half a million, Africa makes progress: WHO". reuters.com. Retrieved 13 July 2017. 
  54. ↑ "WHO/UNICEF report: Malaria MDG target achieved amid sharp drop in cases and mortality, but 3 billion people remain at risk". who.int. Retrieved 13 July 2017. 
  55. ↑ "This Could Be the End of Malaria as We Know It". fortune.com. Retrieved 13 July 2017. 
  56. ↑ "Malaria kills a half-million Africans a year. Gene-edited mosquitoes might stop it". statnews.com. Retrieved 14 July 2017. 
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