Difference between revisions of "Timeline of immunology"
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| 1798 || || " Edward Jenner initiates smallpox vaccination."<ref name="History of immunology"/><ref name="The Complete Idiot's Guide to Food Allergies">{{cite book |last1=Rejaunier |first1=Jeanne |last2=Freund |first2=Lee |title=The Complete Idiot's Guide to Food Allergies |url=https://books.google.com.ar/books?id=JkcDGlqwgGQC&pg=PA18&dq=1900+Paul+Ehrlich+theorizes+specific+antibody+formation&hl=en&sa=X&ved=0ahUKEwjfrYyQ_8zcAhUFEZAKHbJQBEUQ6AEIKDAA#v=onepage&q=1900%20Paul%20Ehrlich%20theorizes%20specific%20antibody%20formation&f=false}}</ref> || | | 1798 || || " Edward Jenner initiates smallpox vaccination."<ref name="History of immunology"/><ref name="The Complete Idiot's Guide to Food Allergies">{{cite book |last1=Rejaunier |first1=Jeanne |last2=Freund |first2=Lee |title=The Complete Idiot's Guide to Food Allergies |url=https://books.google.com.ar/books?id=JkcDGlqwgGQC&pg=PA18&dq=1900+Paul+Ehrlich+theorizes+specific+antibody+formation&hl=en&sa=X&ved=0ahUKEwjfrYyQ_8zcAhUFEZAKHbJQBEUQ6AEIKDAA#v=onepage&q=1900%20Paul%20Ehrlich%20theorizes%20specific%20antibody%20formation&f=false}}</ref> || | ||
| + | |- | ||
| + | | 1840 || || German physician {{w|Friedrich Gustav Jakob Henle}} proposes a {{w|germ theory of disease}}. || | ||
|- | |- | ||
| 1877 || || German Jewish physician Paul Ehrlich first describes mast cells.<ref>{{cite book |last1=McCance, |first1=Kathryn L. |last2=Huether |first2=Sue E. |title=Pathophysiology E-Book: The Biologic Basis for Disease in Adults and Children |url=https://books.google.com.ar/books?id=0fskCwAAQBAJ&pg=PA195&dq=1877+Paul+Ehrlich+recognizes+mast+cells&hl=en&sa=X&ved=0ahUKEwjx64P7ps3cAhXBhJAKHY7DDBQQ6AEIKDAA#v=onepage&q=1877%20Paul%20Ehrlich%20recognizes%20mast%20cells&f=false}}</ref><ref name="History of immunology"/> || | | 1877 || || German Jewish physician Paul Ehrlich first describes mast cells.<ref>{{cite book |last1=McCance, |first1=Kathryn L. |last2=Huether |first2=Sue E. |title=Pathophysiology E-Book: The Biologic Basis for Disease in Adults and Children |url=https://books.google.com.ar/books?id=0fskCwAAQBAJ&pg=PA195&dq=1877+Paul+Ehrlich+recognizes+mast+cells&hl=en&sa=X&ved=0ahUKEwjx64P7ps3cAhXBhJAKHY7DDBQQ6AEIKDAA#v=onepage&q=1877%20Paul%20Ehrlich%20recognizes%20mast%20cells&f=false}}</ref><ref name="History of immunology"/> || | ||
|- | |- | ||
| − | | | + | | 1878 || || {{w|Louis Pasteur}} confirms and popularizes the {{w|germ theory of disease}}. || |
|- | |- | ||
| 1883 || || Russian zoologist {{w|Ilya Ilyich Mechnikov}} theorizes that cells are involved in the defense of the body.<ref name="History of immunology"/><ref name="The Complete Idiot's Guide to Food Allergies"/> || | | 1883 || || Russian zoologist {{w|Ilya Ilyich Mechnikov}} theorizes that cells are involved in the defense of the body.<ref name="History of immunology"/><ref name="The Complete Idiot's Guide to Food Allergies"/> || | ||
Revision as of 19:12, 1 August 2018
This is a timeline of immunology.
Contents
Big picture
| Time period | Development summary |
|---|
Full timeline
| Year | Event type | Details | Country/region |
|---|---|---|---|
| 430 BC | "Nevertheless, there were intimations as early as 430 B.C. that if one survived a disease, the person thereafter became "immune" to any subsequent exposures."[1] | ||
| 1700 | "Although most historical accounts credit Edward Jenner for the development of the first immunization process, a previous similar procedure had become established in China by 1700. The technique was called variolation. This was derived from the name of the infective agent—the variola virus."[1] | China | |
| 1798 | " Edward Jenner initiates smallpox vaccination."[1][2] | ||
| 1840 | German physician Friedrich Gustav Jakob Henle proposes a germ theory of disease. | ||
| 1877 | German Jewish physician Paul Ehrlich first describes mast cells.[3][1] | ||
| 1878 | Louis Pasteur confirms and popularizes the germ theory of disease. | ||
| 1883 | Russian zoologist Ilya Ilyich Mechnikov theorizes that cells are involved in the defense of the body.[1][2] | ||
| 1891 | Robert Koch discovers delayed type hypersensitivity.[1][2] | ||
| 1900 | Paul Ehrlich theorizes about some of the events taking place in immune cells, postulating that cells interact with toxins via "side chains" that stem from protoplasm. | ||
| 1902 | Charles Richet coins the term anaphylaxis to describe the most dangerous allergic reaction.[2] | ||
| 1906 | Clemens von Pirquet coins the term allergy.[1][2] | ||
| 1907 | Svante Arrhenius coins the term immunochemistry.[2] | ||
| 1910 | Henry Dale identifies histamine, a body chemical responsible for many allergic reactions. | ||
| 1916 | Robert Cook and Albert Vander Veer demonstrate the role of heredity in allergy sufferers. | ||
| 1921 | Carl Prausnitz and Heinz Küstner discover that components in the blood can reproduce food allergy reactions.[2] | ||
| 1926 | Lloyd D. Felton isolates pure antibody preparation. | ||
| 1934 | John Marrack advances the antigen-antibody binding hypothesis. | ||
| 1937 | David Bovet synthesizes the first antihistamine. | ||
| 1938 | "John Marrack formulates antigen-antibody binding hypothesis."[1] | ||
| 1940 | Karl Landsteiner and Alexander S. Weiner identify Rh antigens. | ||
| 1941 | Albert Coons develops immunofluorescence technique. | ||
| 1942 | "Jules Freund and Katherine McDermott research adjuvants."[1] | ||
| 1948 | Astrid Fagraeus demonstrates the production of antibodies in plasma B cells. | ||
| 1949 | " Macfarlane Burnet & Frank Fenner formulate immunological tolerance hypothesis."[1] | ||
| 1950 | Howard Gershon and Koichi S. Kondo discover suppressor T cells. | ||
| 1953 | J.F. Riley and G.B. West discover histamine in mast cells. | ||
| 1957 | " Alick Isaacs & Jean Lindemann discover interferon (cytokine)."[1] | ||
| 1958 | Jean Dausset discovers human leukocyte antigens. | ||
| 1959 | Rodney Porter discovers antybody structure. | ||
| 1959 | "Niels Jerne, David Talmage, Macfarlane Burnet develop clonal selection theory."[1] | ||
| 1962 | "Rodney Porter and team discovery the structure of antibodies."[1] | ||
| 1962 | "Jaques Miller and team discover thymus involvement in cellular immunity."[1] | ||
| 1962 | "Noel Warner and team distinguish between cellular and humoral immune responses."[1] | ||
| 1964 | Anthony Davis identifies T and B cell cooperation in immune response. | ||
| 1967 | Teruko and Kimishige Ishizaka identify IgE, the allergy antibody. | ||
| 1968 | " Anthony Davis and team discover T cell and B cell cooperation in immune response."[1] | ||
| 1974 | "Rolf Zinkernagel and Peter Doherty explore major histocompatibility complex restriction."[1] | ||
| 1985 | Susumu Tonegawa and Leroy Hood identify immunoglobulin genes."[1] | ||
| 1985 | Leroy Hood identifies genes for the T. cell receptor. | ||
| 1985 | "Scientists begin the rapid identification of genes for immune cells that continues to the present."[1] | ||
| 1987 | " Leroy Hood and team identify genes for the T cell receptor."[1] | ||
| 1990 | Leroy Hood identifies genes for the T. cell receptor. | ||
| 2000 | FDA approves the first anti-IgE drug, rhu-MAb-E25. |
Meta information on the timeline
How the timeline was built
The initial version of the timeline was written by FIXME.
Funding information for this timeline is available.
Feedback and comments
Feedback for the timeline can be provided at the following places:
- FIXME
What the timeline is still missing
Timeline update strategy
See also
External links
References
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 "History of immunology". encyclopedia.com. Retrieved 1 August 2018.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Rejaunier, Jeanne; Freund, Lee. The Complete Idiot's Guide to Food Allergies.
- ↑ McCance,, Kathryn L.; Huether, Sue E. Pathophysiology E-Book: The Biologic Basis for Disease in Adults and Children.
