Timeline of malaria in 2015

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This is a timeline of malaria in 2015.

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Time period Development summary

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Year/period Event type Details
April 24 "The results of final clinical trials of the first viable malaria vaccine show it offers partial protection against malaria for up to four years. The vaccine is called RTS,S and has been developed over two decades by GlaxoSmithKline and a non-profit organization funded by the Bill & Melinda Gates Foundation."[1][2]
July 24 Endorsement European drugs regulators recommend RTS,S (trade name Mosquirix), as safe and effective to use in babies in Africa at risk of the mosquito-borne disease.[3]
October 5 Award Chinese pharmaceutical chemist Tu Youyou is awarded the 2015 Nobel Prize in Physiology or Medicine "for her discoveries concerning a novel therapy against Malaria". Youyou discovered artemisinin (also known as qinghaosu) and dihydroartemisinin.[4][5]
November 23 Scientific development (vector) Research team from the University of California uses CRISPR-Cas9 genome-editing method to insert a package of new genes into 680 embryos of Anopheles stephensi with the purpose of altering their DNA in order to block the parasite that carries malaria, and having within a few generations virtually all the insects’ descendants the antimalaria DNA inherited. The researchers would discuss the possibility that lab-engineered insects could be released into the wild to stop malaria.[6] California
December The World Health Organization officially certifies the Republic of Maldives as the first malaria-free country in the South-East Asia WHO Region.[7] Maldives
December Report The World Malaria Report is published. A total of 438,000 deaths due to malaria are reported worldwide during the year, with most occuring in the African Region (90%), followed by the South-East Asia Region (7%) and the Eastern Mediterranean Region (2%).[8][9] "Other key findings":" In 2015, 89% of all malaria cases and 91% of deaths were in sub-Saharan Africa.""Of the 106 countries and territories with malaria transmission in 2000, 102 are projected to reverse the incidence of malaria by the end of 2015.""Between 2000 and 2015, the proportion of children under 5 sleeping under an ITN in sub-Saharan Africa increased from less than 2% to an estimated 68%.""1 in 4 children in sub-Saharan Africa still lives in a household with no ITN and no protection provided by indoor residual spraying."[10]
December 8 "On Monday, scientists from Imperial College London announced in the journal Nature Biotechnology that they had successfully genetically modified Anopheles gambiae, the mosquito that is a major malaria vector, to carry infertile traits. The modification process uses a breakthrough technology called CRISPR, a genome editing tool."[11]

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