Timeline of immunology
From Timelines
This is a timeline of immunology.
Contents
Big picture
| Time period | Development summary |
|---|
Full timeline
| Year | Event type | Details | Country/region |
|---|---|---|---|
| 430 BC | "Nevertheless, there were intimations as early as 430 B.C. that if one survived a disease, the person thereafter became "immune" to any subsequent exposures."[1] | ||
| 1700 | "Although most historical accounts credit Edward Jenner for the development of the first immunization process, a previous similar procedure had become established in China by 1700. The technique was called variolation. This was derived from the name of the infective agent—the variola virus."[1] | China | |
| 1798 | " Edward Jenner initiates smallpox vaccination."[1][2] | ||
| 1877 | "Paul Ehrlich recognizes mast cells."[1] | ||
| 1879 | " Louis Pasteur develops an attenuated chicken cholera vaccine."[1] | ||
| 1883 | " Elie Metchnikoff develops cellular theory of vaccination."[1] | ||
| 1891 | " Robert Koch explored delayed type hypersensitivity."[1] | ||
| 1900 | Paul Ehrlich theorizes about some of the events taking place in immune cells, postulating that cells interact with toxins via "side chains" that stem from protoplasm. | ||
| 1906 | "Clemens von Pirquet coined the word allergy."[1] | ||
| 1938 | "John Marrack formulates antigen-antibody binding hypothesis."[1] | ||
| 1942 | "Jules Freund and Katherine McDermott research adjuvants."[1] | ||
| 1949 | " Macfarlane Burnet & Frank Fenner formulate immunological tolerance hypothesis."[1] | ||
| 1957 | " Alick Isaacs & Jean Lindemann discover interferon (cytokine)."[1] | ||
| 1959 | "Niels Jerne, David Talmage, Macfarlane Burnet develop clonal selection theory."[1] | ||
| 1962 | "Rodney Porter and team discovery the structure of antibodies."[1] | ||
| 1962 | "Jaques Miller and team discover thymus involvement in cellular immunity."[1] | ||
| 1962 | "Noel Warner and team distinguish between cellular and humoral immune responses."[1] | ||
| 1968 | " Anthony Davis and team discover T cell and B cell cooperation in immune response."[1] | ||
| 1974 | "Rolf Zinkernagel and Peter Doherty explore major histocompatibility complex restriction."[1] | ||
| 1985 | " Susumu Tonegawa, Leroy Hood, and team identify immunoglobulin genes."[1] | ||
| 1985 | "Scientists begin the rapid identification of genes for immune cells that continues to the present."[1] | ||
| 1987 | " Leroy Hood and team identify genes for the T cell receptor."[1] |
Meta information on the timeline
How the timeline was built
The initial version of the timeline was written by FIXME.
Funding information for this timeline is available.
Feedback and comments
Feedback for the timeline can be provided at the following places:
- FIXME
