Timeline of hemophilia

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This is a timeline of hemophilia.

Big picture

Time period Development summary.
20th century Until the early 1900s, there is no way to store blood for hemophiliacs so they are generally given a transfusion from a family member if they have suffered a trauma. At this point, the life expectancy for boys with hemophilia is around 13 years old. Some of the early treatments include lime, bone marrow, oxygen, thyroid gland, hydrogen peroxide or gelatin. In the 1930s, snake venom is used to help blood clotting. Hospital-based plasma transfusions are common treatments for hemophiliacs in the late 1920s and continue until the 1950s. The different factor deficiencies are distinguished in the 1950s and 1960s. By 1960, the life expectancy of a person with severe hemophilia rises to just under 20 years old.[1]

Full timeline

Year Event type Details Location
1803 Dr. John Conrad Otto from Philadelphia publishes a paper about a familial bleeding disorder that only affected male members.[1] United States
1828 "The term hemophilia comes from a student of Zurich University, Friedrich Hopff and his professor, Dr. Schonlein, who came up with the term “haemorrhaphilia” which became “haemophilia” in 1828."[1]
1930 Scientists learn how to separate blood into its major parts, plasma and red cells.[2]
1947 "Argentinian physician, Alfredo Pavlovsky discovered there were two types of hemophilia (A and B) in 1947."[1] Argentina
1965 Dr. Judith Graham Pool from Stanford University discovers a process of freezing and thawing plasma to get a layer of factor-rich plasma (cryoprecipitate).[2] Graham Pool discovers that the cryoprecipitate left from thawing plasma is high in factor VIII. This could be infused to control heavy bleeding allowing blood banks to produce and store large amounts for use in surgical procedures for hemophiliacs.[1] United States

Meta information on the timeline

How the timeline was built

The initial version of the timeline was written by FIXME.

Funding information for this timeline is available.

Feedback and comments

Feedback for the timeline can be provided at the following places:

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What the timeline is still missing

Timeline update strategy

See also

External links

References

  1. 1.0 1.1 1.2 1.3 1.4 "A Brief History of Hemophilia Treatment". hemophilianewstoday.com. Retrieved 22 October 2018. 
  2. 2.0 2.1 "The History of Hemophilia". hog.org. Retrieved 22 October 2018.