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| 2000 || || USAID funds a large regional anti-trafficking effort for South Asia, managed by the {{w|United Nations Development Fund for Women}} (UNIFEM), focused on prevention and education in {{w|Bangladesh}}, {{w|India}}, {{w|Nepal}}, {{w|Pakistan}} and {{w|Sri Lanka}}.<ref>{{cite web |title=Trafficking in Persons: USAID’s Response |url=http://www.childtrafficking.org/pdf/user/trafficking%20_in_persons_usaids_response.pdf |website=childtrafficking.org |accessdate=17 April 2019}}</ref> || {{w|South Asia}}
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| 2001 || || USAID creates the West Africa Regional Program headquartered in {{w|Bamako}}, {{w|Mali}}. This program is aimed at working on regional issues supported through a regional approach. It provides capacity building support for the Economic Community of West African States, and support to the West African Power Pool project.<ref>{{cite web |title=HISTORY |url=https://www.usaid.gov/history-13 |website=usaid.gov |accessdate=17 April 2019}}</ref> || {{w|Mali}}
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| 2003 || || {{w|United States President}} {{w|George W. Bush}} establishes PEPFAR, the {{w|President's Emergency Plan for AIDS Relief}}, putting USAID's HIV/AIDS programs under the direction of the State Department's new Office of the {{w|Global AIDS Coordinator}}.<ref>{{cite web |url=http://www.pepfar.gov/agencies/c19390.htm |title=Department of State (DoS) |publisher=Pepfar.gov |date=2006-11-15 |accessdate=2011-03-12 |archive-url=https://web.archive.org/web/20110728032409/http://www.pepfar.gov/agencies/c19390.htm |archive-date=2011-07-28 |dead-url=yes }} For the nature of the emergency and the U.S. Government response, see {{cite web |last1=U.S. Government Accountability Office |title=Intellectual Property: U.S. Trade Policy Guidance on WTO Declaration on Access to Medicines May Need Clarification (GAO-07-1198) |url=https://www.gao.gov/assets/270/267756.pdf |accessdate=30 March 2019 |date=September 2007}}</ref> ||
