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Timeline of brain preservation

805 bytes added, 00:20, 4 February 2019
Full timeline: added some notable events, removed some less notable ones
| 1773-04 || cryonics || futurism || || {{W|Benjamin Franklin}} || In a letter to Jacques Dubourg, {{W|Benjamin Franklin}} says: "I wish it were possible&nbsp;...to invent a method of embalming drowned persons, in such a manner that they might be recalled to life at any period, however distant; for having a very ardent desire to see and observe the state of America a hundred years hence, I should prefer to an ordinary death, being immersed with a few friends in a cask of Madeira, until that time, then to be recalled to life by the solar warmth of my dear country! But&nbsp;... in all probability, we live in a century too little advanced, and too near the infancy of science, to see such an art brought in our time to its perfection&nbsp;...".<ref>{{Cite web|url=https://en.wikisource.org/wiki/Page:Works_of_the_Late_Doctor_Benjamin_Franklin_(1793).djvu/233|title=Page:Works of the Late Doctor Benjamin Franklin (1793).djvu/233 - Wikisource, the free online library|website=en.wikisource.org|access-date=2019-01-21}}</ref>
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| 1883-04-15 || cryogenics || technological development || cold || {{W|Jagiellonian University}} || Nitrogen is liquefied by {{W|Zygmunt Wróblewski}} and {{W|Karol Olszewski}} at the {{W|Jagiellonian University}}.<ref>{{cite book|url=https://books.google.com/books?id=8SKrWdFLEd4C&pg=PA249|page=249|title=A Short History of the Progress of Scientific Chemistry in Our Own Times|author=Tilden, William Augustus |publisher=BiblioBazaar, LLC|year=2009|isbn=1-103-35842-1}}</ref>
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| 1968 1931-07 || cryonics || organisation writing || fiction || {{W|Robert Ettinger}} || {{W|Robert Ettinger}} reads Neil R. Jones' newly published story, "The Jameson Satellite",<ref name="regis87">{{cite book |title= Great Mambo Chicken and the Transhuman Condition: Science Slightly Over The Edge| Cryo-Care Equipment Corporation last= Regis|first= Ed| authorlink=Ed Hope closes CryoRegis (author) |coauthors= |year= 1991|publisher= Westview Press|location= |isbn= 0-Care Equipment Corporation after seeing 201-56751-2|page= |pages= 87–88|url= }}</ref>, in which a professor has his corpse sent into earth orbit where it wouldn't turn would remain preserved indefinitely at near absolute zero (note: this is not scientifically accurate), until millions of years later, when, with humanity extinct, a race of mechanical beings discovers, revives, and repairs him by transferring his brain in a profit. The remaining patients are turn over to other organizations or to relativesmechanical body.<ref name="SuspensionFailuresRCWE">{{Cite cite web| title = {{W| Robert Ettinger}} | publisher = Cryonics Institute |url=httpshttp://www.alcorcryonics.org/Library/html/suspensionfailuresbio.html#Robert_Ettinger | accessdate = May 24, 2009 |titledeadurl =Suspension Failures - Lessons from the Early Daysyes |websitearchiveurl = https://www.webcitation.org/6ASYHJ6M9?url=http://www.alcorcryonics.org/bio.html#Robert_Ettinger | archivedate = September 5, 2012 |access-datedf =2019-01mdy-21all }}</ref>
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| 1931-07 1938 || cryonics cryobiology || writing || fiction || {{W|Robert Ettinger}} || {{W|Robert Ettinger}} reads Neil RAlexander Goetz and S. Jones' newly published story, "The Jameson Satellite",<ref name="regis87">{{cite book |title= Great Mambo Chicken Scott Goetz publish a paper discussing vitrification and the Transhuman Condition: Science Slightly Over The Edge|last= Regis|first= Ed|authorlink=Ed Regis (author) |coauthors= |year= 1991|publisher= Westview Press|location= |isbn= 0-201-56751-2|page= |pages= 87–88|url= }}</ref>, in which a professor has his corpse sent into earth orbit where it would remain preserved indefinitely crystallization of organic cells at near absolute zero (note: this is not scientifically accurate), until millions of years later, when, with humanity extinct, a race of mechanical beings discovers, revives, and repairs him by transferring his brain in a mechanical body.<ref name="RCWE">{{cite web | title = {{W| Robert Ettinger}} | publisher = Cryonics Institute | url = http://www.cryonics.org/bio.html#Robert_Ettinger | accessdate = May 24, 2009 | deadurl = yes | archiveurl = https://www.webcitation.org/6ASYHJ6M9?url=http://wwwlow temperatures.cryonics.org/bio.html#Robert_Ettinger | archivedate = September 5, 2012 | df = mdy-all }}</ref>
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| 1950-05 || cryobiology || technological development || vitrification || Luyet, Gonzales || Luyet and Gonzales achieve successful vitrification of chicken embryo hearts using ethylene glycol.<ref>{{Cite journal|last=Gonzales|first=F.|last2=Luyet|first2=B.|date=1950-5|title=Resumption of heart-beat in chick embryo frozen in liquid nitrogen|url=https://www.ncbi.nlm.nih.gov/pubmed/15426631|journal=Biodynamica|volume=7|issue=126-128|pages=1–5|issn=0006-3010|pmid=15426631}}</ref>
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| 1954-06 || cryobiology suspended animation || science || nature || Smith et al. || Smith et al., demonstrate the ability of golden hamsters to recover and survive long term following freezing of ~60% of the water in their brains and the survival a full recovery of hamsters cooled to -5°C.<ref>{{Cite journal|last=Parkes|first=A. S.|last2=Lovelock|first2=J. E.|last3=Smith|first3=A. U.|date=1954-06|title=Resuscitation of Hamsters after Supercooling or Partial Crystallization at Body Temperatures Below 0° C.|url=https://www.nature.com/articles/1731136a0|journal=Nature|language=en|volume=173|issue=4415|pages=1136–1137|doi=10.1038/1731136a0|issn=1476-4687}}</ref>
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| 1959-05 || cryobiology || technological development || vitrification || Lovelock, Bishop || Lovelock and Bishop discover the cryoprotective properties of dimethyl sulfoxide (Me2SO). Me2SO would subsequently become a mainstay of most experimental vitrification solutions used in organ preservation.<ref>{{Cite journal|last=LOVELOCK|first=J. E.|last2=BISHOP|first2=M. W. H.|date=1959-05|title=Prevention of Freezing Damage to Living Cells by Dimethyl Sulphoxide|url=http://dx.doi.org/10.1038/1831394a0|journal=Nature|volume=183|issue=4672|pages=1394–1395|doi=10.1038/1831394a0|issn=0028-0836}}</ref>
| 2010-07 || cryobiology || technological development || toxicity || Fahy, et al. || Fahy, et al., make significant advances in neutralizing cryoprotectant toxicity.<ref>{{Cite journal|last=Fahy|first=Gregory M.|date=2010-7|title=Cryoprotectant toxicity neutralization|url=https://www.ncbi.nlm.nih.gov/pubmed/19501081|journal=Cryobiology|volume=60|issue=3 Suppl|pages=S45–53|doi=10.1016/j.cryobiol.2009.05.005|issn=1090-2392|pmid=19501081}}</ref>
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| 20152012-1203-12 22 || cryonics || organisation || || CryoCare {{W|Alcor Life Extension Foundation}} | CryoCare preserves their | Fred Chamberlain III, a co-founder of Alcor, becomes the first patientto be demonstrably preserved free of ice formation as would observe from CT scans in 2018.<ref name="CryoCareFirst"/>
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| 2017-03 || cryobiology || technological development || re-warming || Bischoff, et al. || Bischoff, et al., develop a novel technique of inductive heat re-warming using magnetic nanoparticles in the vasculature allowing for uniform re-warming of organs the size of rabbit kidneys at rates high enough to prevent devitrification of M-22 vitrification solution at a concentration compatible with kidney viability. The system is potentially applicable to larger organs, such as the human brain.<ref>{{Cite journal|last=Manuchehrabadi|first=Navid|last2=Gao|first2=Zhe|last3=Zhang|first3=Jinjin|last4=Ring|first4=Hattie L.|last5=Shao|first5=Qi|last6=Liu|first6=Feng|last7=McDermott|first7=Michael|last8=Fok|first8=Alex|last9=Rabin|first9=Yoed|date=03 01, 2017|title=Improved tissue cryopreservation using inductive heating of magnetic nanoparticles|url=https://www.ncbi.nlm.nih.gov/pubmed/28251904|journal=Science Translational Medicine|volume=9|issue=379|doi=10.1126/scitranslmed.aah4586|issn=1946-6242|pmc=PMC5470364|pmid=28251904}}</ref><ref>{{Cite web|url=https://www.ibtimes.co.uk/organ-cryopreservation-becoming-reality-bringing-whole-bodies-back-still-100-years-away-1609149|title=Organ cryopreservation is becoming a reality – but bringing whole bodies back still 100 years away| 2012date=2017-03-22 01|website=International Business Times UK| cryonics language=en|| || || {{W|Alcor Life Extension Foundationaccess-date=2019-02-04}} || Fred Chamberlain III, a co-founder of Alcor, becomes the first patient to be demonstrably preserved free of ice formation as would observe from CT scans in 2018.</ref>
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| 2018 || cryonics || quality assessment || scan || Darwin || M. Darwin publishes “Preliminary Evaluation of Alcor Patient Cryogenic CT Scans” analyzing three of the four available Alcor neuropatient CT scans. Darwin concludes that it is highly likely that Alcor patient A-1002 was possibly the first human cryonics patient to achieve essentially ice free brain cryopreservation.<ref>{{Cite web|url=https://spaces.hightail.com/receive/qqSYgDnnI1|title=Preliminary Evaluation of Alcor Patient Cryogenic CT Scans|last=Darwin|first=Michael|date=|website=|archive-url=|archive-date=|dead-url=|access-date=}}</ref>
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| 1963 || cryonics || organisation || founding || {{W|Life Extension Society}} || During the conference, the {{W|Life Extension Society}}, the first cryonics organization, is founded by Evan Cooper. It would be situated in Washington, D.C.<ref name="EvCooperClassic"/>
 
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| 1963-12-29 || cryonics || social || conference || || The first cryonics conference happens.<ref name="cryonics9208"/><ref name="firstNewsletter">{{Cite web|url=http://www.evidencebasedcryonics.org/2011/01/19/the-first-cryonics-newsletter/|title=The First Cryonics Newsletter|last=Perry|first=Mike|date=2011-01-19|website=Evidence Based Cryonics|archive-url=https://web.archive.org/web/20161126064131/http://www.evidencebasedcryonics.org/2011/01/19/the-first-cryonics-newsletter/|archive-date=2016-11-26|dead-url=|access-date=}}</ref>
6 days later, relatives would move Bedford to the Cryo-Care facility in Phoenix. Later, his son would store him, and finally on September 22, 1987, Bedford would be moved to Alcor.<ref name="BedfordSuspension"/><ref name="AlcorCase">{{Cite web|url=https://alcor.org/cases.html|title=Alcor Cases|website=alcor.org|access-date=2019-01-22}}</ref>
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| 1968 || cryonics || organisation || || Cryo-Care Equipment Corporation || Ed Hope closes Cryo-Care Equipment Corporation after seeing it wouldn't turn a profit. The remaining patients are turn over to other organizations or to relatives.<ref name="SuspensionFailures">{{Cite web|url=https://www.alcor.org/Library/html/suspensionfailures.html|title=Suspension Failures - Lessons from the Early Days|website=www.alcor.org|access-date=2019-01-21}}</ref>
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| 1968 || cryobiology || technological development || cryoprotection || || Dog kidneys are cryopreserved using Farrant's technique resulting in no ice formation and with excellent structural preservation, and the ability to tolerate reperfusion with blood in the animal without immediate failure.<ref>{{Cite journal|last=Kemp|first=E.|last2=Clark|first2=P. B.|last3=Anderson|first3=C. K.|last4=Laursen|first4=T.|last5=Parsons|first5=F. M.|date=1968|title=Low temperature preservation of mammalian kidneys|url=https://www.ncbi.nlm.nih.gov/pubmed/4893380|journal=Scandinavian Journal of Urology and Nephrology|volume=2|issue=3|pages=183–190|issn=0036-5599|pmid=4893380}}</ref>
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| 1973-08 || cryobiology || technological development || cryoprotection, re-warming || Hamilton, Lehr || Hamilton and Lehr demonstrate successful preservation of canine small intestine allografts using Me2SO as the cryoprotectant, and cooling and warming using vascular perfusion with helium gas suggesting that even controlled cooling and emptying of the vasculature's fluid/ice are beneficial in organ freezing. The organ is successfully transplanted.<ref>{{Cite journal|last=LaRossa|first=D.|last2=Hamilton|first2=R.|last3=Ketterer|first3=F.|last4=Lehr|first4=H. B.|date=1973-08|title=Preservation of structure and function in canine small intestinal autografts after freezing|url=https://www.ncbi.nlm.nih.gov/pubmed/4722678|journal=Plastic and Reconstructive Surgery|volume=52|issue=2|pages=174–177|issn=0032-1052|pmid=4722678}}</ref><ref>{{Cite web|url=https://www.journalofsurgicalresearch.com/action/captchaChallenge?redirectUri=%2Farticle%2F0022-4804%2873%2990033-4%2Fpdf|title=Journal of Surgical Research|website=www.journalofsurgicalresearch.com|doi=10.1016/0022-4804(73)90033-4|access-date=2019-01-22}}</ref>
 
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| 1974 || cryonics || organisation || || Trans Time || Due to the closure of the storage facility in New York, the Bay Area Cryonics Society and the {{W|Alcor Life Extension Foundation}} change their plan to preserve their patients to the Trans Time facility instead of the New York one, and would do so until the 1980s.<ref name="BenBestCryonicsHistory"/>
| 1982 || cryobiology || science || toxicity || Fahy, et al. || Fahy, et al., publish papers which extensively documents the role of cryoprotectant toxicity as a barrier to tissue and organ cryopreservation suggest possible molecular mechanisms.<ref>{{Citation|last=Fahy|first=G. M.|title=Prospects for organ preservation by vitrification|date=1982|url=http://dx.doi.org/10.1007/978-94-011-6267-8_60|work=Organ Preservation|pages=399–404|publisher=Springer Netherlands|isbn=9789401162692|access-date=2019-02-01|last2=Hirsch|first2=A.}}</ref><ref>{{Cite journal|last=Fahy|first=Gregory M.|last2=Lilley|first2=Terence H.|last3=Linsdell|first3=Helen|last4=Douglas|first4=Mary St.John|last5=Meryman|first5=Harold T.|date=1990-06|title=Cryoprotectant toxicity and cryoprotectant toxicity reduction: In search of molecular mechanisms|url=http://dx.doi.org/10.1016/0011-2240(90)90025-y|journal=Cryobiology|volume=27|issue=3|pages=247–268|doi=10.1016/0011-2240(90)90025-y|issn=0011-2240}}</ref>
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| 1982 || cryonics || organisation || || {{W|Alcor Life Extension Foundation}} || Alcor begins storing its own patients. It was previously storing its patients with Trans Time, Inc. 
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| 1982 || cryonics || organisation || || {{W|Alcor Life Extension Foundation}} || The Institute for Advanced Biological Studies merges with Alcor.
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| 1986 || cryonics || organisation || organisation's first || {{W|Alcor Life Extension Foundation}} || Alcor cryopreserves a member's companion animal for the first time.
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| 1986 || cryonics || futurism || || Drexler || Aldehyde-stabilized cryopreservation is proposed under the name of "fixation and vitrification".<ref>{{Cite book|title=Engines of Creation: The Coming Era of Nanotechnology|last=Drexler|first=K. Eric|publisher=|year=1986|isbn=|location=|pages=|chapter=9|url=http://e-drexler.com/d/06/00/EOC/EOC_Chapter_9.html}}</ref>
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| 1987 || cryonics || organisation || founding || Cryonics Society of Canada || Douglas Quinn launches the Cryonics Society of Canada and Canadian Cryonics News.<ref>{{Cite web|url=http://www.cryocdn.org/cdnhist.html|title=Cryonics Society of Canada -- The Story of the Organization and Its People|website=www.cryocdn.org|access-date=2019-01-22}}</ref>
| 1989 || cryonics || technological development || cooling rate || Darwin || M. Darwin creates the portable ice bath (PIB) to substantially increase the efficacy of external cooling with Fred Chamberlain subsequently developing a surface convective cooling device to further improve heat exchange doubling the rate of cooling during external cooling for induction of hypothermia.<ref>{{Cite journal|last=Pizer|first=David|date=1989|title=Alcor outstanding support award nominee|url=https://www.alcor.org/cryonics/cryonics8907.txt|journal=Cryonics|volume=17|issue=7|pages=10|via=}}</ref>
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| 1989 || cryonics || technological adoption || || Darwin || M. Darwin introduces high impulse [[wikipedia:cardiopulmonary resuscitation|cardiopulmonary resuscitation]] (CPR) improving cardiac output during cardiopulmonary support (CPS).<ref>{{Cite journal|last=Darwin|first=M.|date=1989|title=A major advance in suspension patient support|url=http://www.alcor.org/cryonics/cryonics8908.txt|journal=Cryonics|volume=10|issue=8|pages=7-14|access-date=2010-09-29|via=}}</ref>
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| 1980s (late) || cryonics || legal || || {{W|Alcor Life Extension Foundation}} || Alcor Member Dick Clair{{snd}}who was dying of AIDS{{snd}}fights in court for the legal right to practice cryonics in California, a battle that would ultimately be won.<ref name="BenBestCryonicsHistory"/>
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| 2001 || cryonics || technological adoption || vitrification || {{W|Alcor Life Extension Foundation}} || Alcor begins {{W|vitrification}} perfusion of cryonics patients with a cryoprotectant mixture called B2C, which is developed by 21st Century Medicine.<ref name="BenBestCryonicsHistory"/><ref>{{Cite web|url=https://www.alcor.org/Library/html/newtechnology.html|title=New Cryopreservation technology.|last=|first=|date=2005-10|website=Alcor News|archive-url=|archive-date=|dead-url=|access-date=}}</ref>
 
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| 2002 || cryonics || science || paper || || For the first time, a paper shows rigorous demonstration of memory retention after cooling to +10°C (59°F): "Learning and memory is preserved after induced asanguineous hyperkalemic hypothermic arrest in a swine model of traumatic exsanguination".<ref>{{Cite web|url=https://www.surgjournal.com/action/captchaChallenge?redirectUri=%2Farticle%2FS0039-6060%2802%2900085-5%2Ffulltext|title=Surgery|website=www.surgjournal.com|access-date=2019-01-22}}</ref>
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| 2003-06 || cryonics || technological adoption || intermediate storage temperature || {{W|Alcor Life Extension Foundation}} || {{W|Brian Wowk}}, Mike Iarocci, and Stephen Valentine present new designs for intermediate temperature storage systems to the Alcor board of directors. Alcor acquires an experimental single-patient "neuropod" intermediate temperature storage system developed by {{W|Brian Wowk}} at 21CM.<ref name="IntermediateTemperatureStorage"/>
 
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| 2003-08 || cryobiology || R&D || intermediate storage temperature || {{W|Carnegie Mellon University}} || {{W|Carnegie Mellon University}} receives a $1.3 million grant from the U.S. government to study fracturing during {{W|vitrification}} of tissue for medical applications, which would considerably advance the field.<ref name="IntermediateTemperatureStorage"/>
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| 2005 || cryonics || organisation || founding || OregonCryo || Oregon Cryonics is established as a Non Profit Mutual Benefit corporation.<ref>{{Cite web|url=http://www.oregoncryo.com/aboutOC.html|title=Oregon Cryonics - About OC|website=www.oregoncryo.com|access-date=2019-01-22}}</ref>
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| 2005-02 || cryonics || organisation || || Sociedad Crionica || The website crionica.org is created.<ref name="CI2017-4">{{Cite journal|last=Tripplett|first=Donald|date=2017|title=Sociedad Crionica|url=https://www.cryonics.org/images/uploads/magazines/CI-NEWS-04-2017.pdf|journal=Cryonics Institute Newsletter|volume=|issue=4|pages=27|via=}}</ref>
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| 2005 (mid) || cryonics || organisation || founding || Neural Archives Foundation || The Neural Archives Foundation is conceived. The organisation offers brain preservation services. In 2008 it would be incorporated.<ref name="fieldcryoprotection">{{Cite web|url=http://neuralarchivesfoundation.org/|title=NAF|website=neuralarchivesfoundation.org|access-date=2019-01-22}}</ref>
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| 2008 || cryonics || organisation || first || Neural Archives Foundation || Neural Archives Foundation preserves its first human patient.<ref>{{Cite web|url=http://www.neuralarchivesfoundation.org/about|title=NAF|website=www.neuralarchivesfoundation.org|access-date=2019-01-22}}</ref>
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| 2008-12-12 || cryonics || popularisation || || LessWrong || Robin Hanson, talking about Eliezer Yudkowsky and himself, writes [http://www.overcomingbias.com/2008/12/we-agree-get-froze.html We Agree: Get Froze]. Eliezer Yudkowsky would go on writing [https://wiki.lesswrong.com/wiki/Cryonics#Blog_posts various articles about cryonics], which would spawn a lot of interest in the topic by people in the LessWrong community{{snd}}in 2013, 13% of "experienced" respondents to a LessWrong survey (that were part of the community for over two years and had over 1000 karma) reported being signed up for cryonics.<ref>{{Cite web|url=https://www.lesswrong.com/posts/Gh2qQHrCg3teQen3c/rationalists-are-less-credulous-but-better-at-taking-ideas|website=www.lesswrong.com|access-date=2019-02-04}}</ref>
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| 2009 || cryonics || science || || || A vital mammalian organ is successfully vitrified, transplanted, and reused for the first time.<ref>{{Cite journal|last=Fahy|first=Gregory M.|last2=Wowk|first2=Brian|last3=Pagotan|first3=Roberto|last4=Chang|first4=Alice|last5=Phan|first5=John|last6=Thomson|first6=Bruce|last7=Phan|first7=Laura|date=July 2009|title=Physical and biological aspects of renal vitrification|url=http://dx.doi.org/10.4161/org.5.3.9974|journal=Organogenesis|volume=5|issue=3|pages=167–175|doi=10.4161/org.5.3.9974|issn=1547-6278}}</ref>
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| 2013 || cryobiology || science || vitrification || Fahy, et al. || Fahy, et al., demonstrate recovery of LTP memory electrophysiology for half millimeter thick hippocampal brain slices that had previously been vitrified and stored for weeks.<ref>{{Cite journal|last=Fahy|first=Gregory M.|last2=Guan|first2=Na|last3=de Graaf|first3=Inge A. M.|last4=Tan|first4=Yuansheng|last5=Griffin|first5=Lenetta|last6=Groothuis|first6=Geny M. M.|date=2012-10-30|title=Cryopreservation of precision-cut tissue slices|url=http://dx.doi.org/10.3109/00498254.2012.728300|journal=Xenobiotica|volume=43|issue=1|pages=113–132|doi=10.3109/00498254.2012.728300|issn=0049-8254}}</ref>
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| 2013 || life extension || organisation || founding || Church of Perpetual Life || The Church of Perpetual Life is founded. Their first service happens at the end of 2013.<ref>{{Cite web|url=http://www.churchofperpetuallife.org/|title=Church of Perpetual Life|website=Church of Perpetual Life|language=en|access-date=2019-01-22}}</ref><ref>{{Citation|last=Perpetual Life|title=COPL Grand Opening - part 1|url=https://www.youtube.com/watch?v=x_5QmppTsZo|access-date=2019-01-22}}</ref>
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| 2013-05 || cryonics || technological adoption || remote stabilization || Cryonics Institute || The wife of UK cryonicist Alan Sinclair receives a field cryoprotection before being shipped to the Cryonics Institute.<ref name="BenBestCryonicsHistory"/>
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| 2014 || brain preservation || science || || {{W|21st Century Medicine}} || Robert McIntyre from {{W|21st Century Medicine}} wins the Small Mammal Prize from the {{W|Brain Preservation Foundation}} with a technique called vitrifixation, an Aldehyde Stabilized Cryopreservation (ASC). He combines research done by {{W|Greg Fahy}} and Shawn Mikula.<ref name="SmallMammalBrainPrize"/>
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| 2014 || cryonics || organisation || || {{W|Suspended Animation, Inc}} || {{W|Suspended Animation, Inc}} opens an office in California.<ref name="Alcor2018-2">{{Cite web|url=https://issuu.com/alcorlife/docs/cryonics2018-2|title=Cryonics Magazine March-April 2018|website=Issuu|language=en|access-date=2019-01-22}}</ref>
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| 2014-05-06 || cryonics || organisation || || OregonCryo || OregonCryo preserves its first patient, a dog named Cupcake.<ref>{{Cite web|url=http://www.oregoncryo.com/caseReportsPets.html|title=Oregon Cryonics - Pet Case Reports|website=www.oregoncryo.com|access-date=2019-01-22}}</ref>
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| 2016 || brain preservation || organisation || founding || Nectome || Nectome is started by Robert McIntyre after having won the {{W|Brain Preservation Foundation}}'s Large Mammal Prize. Nectome is a research organization developing biological preservation techniques to better preserve the physical traces of memory.<ref name="Nectome">{{Cite web|url=https://nectome.com/|title=Nectome|website=nectome.com|access-date=2019-01-22}}</ref>
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| 2016-03-24 || cryonics || popularisation || || Wait But Why || Tim Urban publishes "[https://waitbutwhy.com/2016/03/cryonics.html Why Cryonics Makes Sense]" on his blog "[https://waitbutwhy.com Wait But Why]". At the moment the artcile as published, 331,824 people were subscribed to receive new posts by email.<ref>{{Cite web|url=https://web.archive.org/web/20160325000246/https://waitbutwhy.com/2016/03/cryonics.html|title=Why Cryonics Makes Sense - Wait But Why|date=2016-03-25|website=web.archive.org|access-date=2019-02-04}}</ref> Cryonicists almost unanimously aclaimed this post as the best introduction to cryonics.
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| 2016-05-06 || cryonics || organisation || training || OregonCryo || OregonCryo starts training its medical team with body donors.<ref name="OregonCryoCaseReports"/>
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| 2016-06-06 || cryonics || risk management || economic stability || {{W|Alcor Life Extension Foundation}} || The Alcor Care Trust Supporting Organization (ACT) is created. The Patient Care Trust (PCT) continues in existence to receive initial funding from new cryopreservations, and to pay for ongoing costs for maintaining patients' cryopreservation. The ACT will make long term investments, continue maintaining the PCT, and possibly eventually fund resuscitation research. Both trusts have different board of directors that can check on each other.<ref>{{Cite web|url=https://alcor.org/Library/html/alcorcaretrust.htm|title=Alcor Care Trust Supporting Organization|website=alcor.org|access-date=2019-01-22}}</ref>
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| 2016-07-30 || cryonics || organisation || founding || Sociedad Crionica || Sociedad Crionica is founded.<ref name="CI2017-4"/>
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| 2016-12-24 || brain preservation || technological adoption || fixation || OregonCryo || For the first time, someone is preserved by being perfused with a fixation solution instead of simply being immersed in it.
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| 2018-05-16 || cryonics || risk management || economic stability || {{W|Alcor Life Extension Foundation}} || Alcor announces the creation of a sibling organisation called the Alcor Endowment Trust Supporting Organization. Its goal is to maintain funds that are invested, and which support Alcor's general operation and research through giving a fraction of the interests made.<ref>{{Cite web|url=https://www.alcor.org/blog/the-alcor-endowment-trust-supporting-organization/|title=The Alcor Endowment Trust Supporting Organization|last=admin|date=2018-05-16|website=Alcor News|language=en-US|access-date=2019-01-22}}</ref>
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| 2018-06-17 || cryonics || organisation || || Yinfeng Life Science Research Institute || The Yinfeng Life Science Research Institute in Jinan, Shandong, China cryopreserves their first patient.<ref>{{Cite web|url=https://www.chinadaily.com.cn/a/201806/26/WS5b319590a3103349141dec01.html|title=Chinese woman's body frozen in advanced procedure - Chinadaily.com.cn|last=李松|website=www.chinadaily.com.cn|access-date=2019-02-04}}</ref> A documentary documents the procedure: [https://vimeo.com/243966672 China Whole Body Cryopreservation].
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| 2018-10-30 || cryonics || legal || || Norman Hardy || For the first time, a cryonics patient uses the Death With Dignity legislation. The patient's name is Norman Hardy.<ref>{{Cite web|url=https://alcor.org/Library/html/casesummary1990.html|title=Alcor Case Summary: A-1990|website=alcor.org|access-date=2019-01-22}}</ref>
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| 2018-11 || cryonics || social || || {{W|Society for Cryobiology}} || The {{W|Society for Cryobiology}} releases a position statement clarifying their stance in regards to cryonics: "The Society recognizes and respects the , saying they respect people's freedom of individuals to hold and express their own opinions and to actin chosing this option, within lawful limitsbut that the procedure is speculative, according to their beliefs. Preferences regarding disposition of postmortem human bodies or brains are clearly a matter of personal choice and, therefore, inappropriate subjects of Society policy. The Society does, however, take the position that the scientific knowledge necessary for the revival of live or dead whole mammals following cryopreservation does not to sucessfully cryopreserve someone doesn't currently exist and can come only from conscientious and patient research in cryobiology and medicine. In short, the act of preserving a body, head or brain after clinical death and storing it indefinitely on the chance that some future generation may restore it to life is an act of speculation or hope, not science, and as such is outside the purview of the Society for Cryobiology."<ref>{{Cite web|url=https://www.societyforcryobiology.org/assets/documents/Position_Statement_Cryonics_Nov_18.pdf|title=Society for Cryobiology Position Statement - Cryonics|last=|first=|date=November 2018|website=Society for Cryobiology|archive-url=|archive-date=|dead-url=|access-date=2019-01-23}}</ref>
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